29 Results for "

FX

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "FX" in MCE Product Catalog:

31
31 Publications Verification
Cat. No.: HY-16214
CAS No.: 213971-34-7
Synonyms: LDHA Inhibitor FX11
FX-11 is a potent, selective, reversible and competitive lactate dehydrogenase A (LDHA) inhibitor, with a Ki of 8 μM. FX-11 reduces ATP levels and induces oxidative stress, ROS production and cell death. FX-11 shows antitumor activity in lymphoma and pancreatic cancer xenografts .
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2
2 Cited Publications
Cat. No.: HY-14852A
CAS No.: 951395-08-7
Purity:  99.79%
Synonyms: FX-1006A
Target:  

Transthyretin (TTR)

Research Areas:  

Neurological Disease

Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis meglumine inhibits amyloidogenesis .
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2
2 Cited Publications
Cat. No.: HY-102027
CAS No.: 1426138-42-2
Purity:  ≥98.0%
Target:  

Bcl-2 Family Apoptosis

Research Areas:  

Cancer

FX1 is a potent and specific BCL6 inhibitor, with an IC50 of around 35 μM.
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1
1 Cited Publications
Cat. No.: HY-153344
CAS No.: 2924573-90-8
Purity:  99.79%
Target:  

PPAR

Research Areas:  

Cancer

FX-909 is a covalent peroxisome proliferator-activated receptor gamma (PPARG) inverse agonist. FX-909 can be used for the research of cancer .
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Cat. No.: HY-106275
CAS No.: 88650-17-3
Purity:  99.98%
Synonyms: Fibrin-derived peptide Bβ15-42
Target:  

Flavivirus Dengue Virus

Research Areas:  

Cardiovascular Disease

FX-06 (Fibrin-derived peptide Bβ15-42) is a fibrin Bbeta chain-derived peptide. FX-06 binds to VE-cadherin and inhibits leukocyte transmigration and initiates VE-cadherin-mediated signaling. FX-06 can be used in the research of ischemia/reperfusion injury, Dengue shock syndrome (DSS) .
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Cat. No.: HY-D1765
CAS No.: 1415018-97-1
FM 1-43FX is a fluorescent membrane probe that contains an aliphatic amine which can react with aldehyde-based fixatives.
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Cat. No.: HY-W014665
CAS No.: 4702-13-0
Synonyms: Phthaloyl glycine
Target:  

Bacterial Fungal

Research Areas:  

Infection

N-Phthaloylglycine (Phthaloyl glycine) is a Type II fragmentary hapten (FX-type) with antimicrobial activity. N-Phthaloylglycine acts against Candida albicans, Escherichia coli, and Staphylococcus epidermidis. N-Phthaloylglycine can be used for the research of fungal and bacterial infection .
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Cat. No.: HY-114511
CAS No.: 1004551-40-9
Purity:  99.90%
Target:  

Factor VIIa

Research Areas:  

Cardiovascular Disease

BMS-593214 is an active site-directed factor (F) VIIa inhibitor. BMS-593214 shows antithrombotic and antihaemostatic properties. BMS-593214 is a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of Viia-activated substrate FX. BMS-593214 prevents electroinduced carotid artery thrombosis (AT) and wire induced vena cava thrombosis (VT) .
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Cat. No.: HY-P991211
CAS No.: 2766038-73-5
Synonyms: STSP-0601

Target:  

Factor XI

Research Areas:  

Cardiovascular Disease

Bemiltenase alfa is a hemostatic agent targeting coagulation factor X (FX). Bemiltenase alfa activates FX and promotes the conversion of prothrombin to thrombin, and thrombin can further transform fibrinogen into fibrin, forming a stable blood clot, thus exerting hemostatic activity. Bemiltenase alfa is promising for research of bleeding symptoms with hemophilia .
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Cat. No.: HY-14852AR
CAS No.: 951395-08-7
Synonyms: FX-1006A (Standard)
Tafamidis meglumine (Standard) is the analytical standard of Tafamidis meglumine. This product is intended for research and analytical applications. Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis meglumine inhibits amyloidogenesis .
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Cat. No.: HY-P991169
CAS No.: 2955620-21-8
Synonyms: NXT007; RG6512; RO7589655

Target:  

Factor Xa Thrombin

Research Areas:  

Cardiovascular Disease

Zemocimig (NXT007) is an activated factor VIII mimetic antibody. Zemocimig binds to FX, FIXa and their activated forms to form a ternary complex, bridges FIXa and FX on the phospholipid surface, and restores intrinsic prothrombinase activity. Zemocimig induces thrombin generation, acts as a procoagulant, antifibrinolytic agent and hemostatic agent, and can shorten aPTT, increase fibrin deposition, correct clotting time, and reduce bleeding parameters. Zemocimig is applicable to the research of hemophilia A .
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Cat. No.: HY-W008234
CAS No.: 3339-73-9
Research Areas:  

Inflammation/Immunology

N-Phthaloyl-β-alanine (hapten FP) is an FX-type hapten without CH2S moiety. N-Phthaloyl-β-alanine can be coupled to OVA using the mixed anhydride method. N-Phthaloyl-β-alanine has more heterologies .
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Cat. No.: HY-168220
CAS No.: 3042887-97-5
Target:  

Deubiquitinase

Research Areas:  

Cancer

FX-171-C is a noncompetitive Deubiquitinase inhibitor with an IC50 of 1.4 µM .
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Cat. No.: HY-167673
CAS No.: 1807639-36-6
Target:  

E1/E2/E3 Enzyme

RNF5-IN-1 (FX12) is a selective RNF5 degrader. RNF5-IN-1 binds to RNF5 and inhibits its E3 activity, and promotes proteasomal degradation of RNF5 in an endoplasmic reticulum (ER)-associated degradation (ERAD) way in cells. RNF5-IN-1 inhibits α-1-antitrypsin (NHK) dislocation with an IC50 value of 2.7 μM. RNF5-IN-1 can be used for research of cystic fibrosis, acute myeloid leukemia, and certain viral infections .
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Cat. No.: HY-RS04624
Research Areas:  

Others

F10 Human Pre-designed siRNA Set A contains three designed siRNAs for F10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17793
Research Areas:  

Others

F10 Mouse Pre-designed siRNA Set A contains three designed siRNAs for F10 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS05391
Research Areas:  

Others

GFUS Human Pre-designed siRNA Set A contains three designed siRNAs for GFUS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS14775
Research Areas:  

Others

TMSB4X Human Pre-designed siRNA Set A contains three designed siRNAs for TMSB4X gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991213
Synonyms: Rixubis

Target:  

Factor XI

Research Areas:  

Cardiovascular Disease

Nonacog gamma is a coagulation factor IX (FIX) supplement. Nonacog gamma activates coagulation factor X (FX), promotes the generation of thrombin, and then converts fibrinogen into fibrin, forming a stable blood clot to exert hemostatic activity. Nonacog gamma is promising for research of hemophilia B .
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Cat. No.: HY-W759458
CAS No.: 113638-96-3
Synonyms: Phthaloyl glycine-13C2,15N
N-Phthaloylglycine- 13C2, 15N (Phthaloyl glycine- 13C2, 15N) is the 13C- and 15N-labeled N-Phthaloylglycine (HY-W014665). N-Phthaloylglycine (Phthaloyl glycine) is an FX-type hapten that attaches to free amine groups of proteins .
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