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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
FX
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "FX" in MCE Product Catalog:
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FX-11 is a potent, selective, reversible and competitive lactate dehydrogenase A (LDHA) inhibitor, with a Ki of 8 μM. FX-11 reduces ATP levels and induces oxidative stress, ROS production and cell death. FX-11 shows antitumor activity in lymphoma and pancreatic cancer xenografts .
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2 Cited Publications
Synonyms: FX-1006A free acid
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Tafamidis (Fx-1006A (free acid)) is an orally active and selective transthyretin (TTR) stabilizer. Tafamidis binds to the thyroxine binding site with negative cooperativity, stabilizes the TTR tetramer, slows TTR tetramer dissociation and subunit exchange, and inhibits TTR fibril formation. Tafamidis can be used in research on nervous system-related diseases .
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Tafamidis meglumine (Fx-1006A) is an orally active and selective transthyretin (TTR) stabilizer. Tafamidis meglumine binds to the thyroxine binding site with negative cooperativity, stabilizes the TTR tetramer, slows TTR tetramer dissociation and subunit exchange, and inhibits TTR fibril formation. Tafamidis meglumine can be used in research on nervous system-related diseases .
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2 Cited Publications
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FX1 is a potent and specific BCL6 inhibitor, with an IC50 of around 35 μM.
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Cat. No.: HY-16723
CAS No.: 1259933-16-8
Synonyms: TV 45070; XEN402; FX301
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Funapide (TV 45070; XEN402) is an orally active inhibitor of voltage-gated sodium channels (VGSC) in the peripheral nervous system with IC50 values ??of 84 nM and 54 nM for Nav1.5 and Nav1.7, respectively. Funapide has analgesic effects .
Synonyms: Fibrin-derived peptide Bβ15-42
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Cat. No.: HY-D1765
CAS No.: 1415018-97-1
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FM 1-43FX is a fluorescent styryl membrane dye that stains lipids green. FM 1-43FX labels extracellular vesicle lipid membranes, exosomes/microvesicles, and various sensory neurons through an endocytosis/vesicle recycling-dependent mechanism, and can label NFH-, calbindin-, and TH-positive mechanoreceptor subtypes. FM 1-43FX acts as a membrane-permeable MET channel blocker, partially inhibiting PIEZO1 and PIEZO2 currents in a voltage-dependent manner, and is used to assess cochlear/zebrafish MET function and detect fungal EV lipid transfer. FM 1-43FX can be used for research on progressive hearing loss .
Cat. No.: HY-W014665
CAS No.: 4702-13-0
Synonyms: Phthaloyl glycine
N-Phthaloylglycine (Phthaloyl glycine) is a Type II fragmentary hapten (FX-type) with antimicrobial activity. N-Phthaloylglycine acts against Candida albicans, Escherichia coli, and Staphylococcus epidermidis. N-Phthaloylglycine can be used for the research of fungal and bacterial infection .
Cat. No.: HY-16723A
CAS No.: 1259933-15-7
Synonyms: (R)-TV 45070; (R)-XEN402; (R)-FX301
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(R)-Funapide ((R)-TV 45070) is the less active R-enantiomer of Funapide. Funapide is a potent inhibitor of the sodium channel Nav1.7, Nav1.8 and other Nav channels expressed in the peripheral nervous system. Fornabil is an orally effective analgesic agent .
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BMS-593214 is an active site-directed factor (F) VIIa inhibitor. BMS-593214 shows antithrombotic and antihaemostatic properties. BMS-593214 is a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of Viia-activated substrate FX. BMS-593214 prevents electroinduced carotid artery thrombosis (AT) and wire induced vena cava thrombosis (VT) .
Cat. No.: HY-14852R
CAS No.: 594839-88-0
Synonyms: FX-1006A free acid (Standard)
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Tafamidis (Standard) (Fx-1006A (free acid) (Standard)) is the analytical standard of Tafamidis (HY-14852). This product is intended for research and analytical applications. Tafamidis (Fx-1006A (free acid)) is an orally active and selective transthyretin (TTR) stabilizer. Tafamidis binds to the thyroxine binding site with negative cooperativity, stabilizes the TTR tetramer, slows TTR tetramer dissociation and subunit exchange, and inhibits TTR fibril formation. Tafamidis can be used in research on nervous system-related diseases .
Cat. No.: HY-14852AR
CAS No.: 951395-08-7
Synonyms: FX-1006A (Standard)
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Tafamidis meglumine (Standard) (Fx-1006A (Standard)) is the analytical standard of Tafamidis meglumine (HY-14852A). This product is intended for research and analytical applications. Tafamidis meglumine (Fx-1006A) is an orally active and selective transthyretin (TTR) stabilizer. Tafamidis meglumine binds to the thyroxine binding site with negative cooperativity, stabilizes the TTR tetramer, slows TTR tetramer dissociation and subunit exchange, and inhibits TTR fibril formation. Tafamidis meglumine can be used in research on nervous system-related diseases .
Cat. No.: HY-14852S
Synonyms: FX-1006A-d3 free acid
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Tafamidis-d3 (Fx-1006A-d3 (free acid)) is the deuterated-labeled Tafamidis (HY-14852). Tafamidis (Fx-1006A (free acid)) is an orally active and selective transthyretin (TTR) stabilizer. Tafamidis binds to the thyroxine binding site with negative cooperativity, stabilizes the TTR tetramer, slows TTR tetramer dissociation and subunit exchange, and inhibits TTR fibril formation. Tafamidis can be used in research on nervous system-related diseases .
Cat. No.: HY-P991211
CAS No.: 2766038-73-5
Synonyms: STSP-0601
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Cat. No.: HY-P991169
CAS No.: 2955620-21-8
Synonyms: NXT007; RG6512; RO7589655
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Zemocimig (NXT007) is an activated factor VIII mimetic antibody. Zemocimig binds to FX, FIXa and their activated forms to form a ternary complex, bridges FIXa and FX on the phospholipid surface, and restores intrinsic prothrombinase activity. Zemocimig induces thrombin generation, acts as a procoagulant, antifibrinolytic agent and hemostatic agent, and can shorten aPTT, increase fibrin deposition, correct clotting time, and reduce bleeding parameters. Zemocimig is applicable to the research of hemophilia A .
Cat. No.: HY-W008234
CAS No.: 3339-73-9
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N-Phthaloyl-β-alanine (hapten FP) is an FX-type hapten without CH2S moiety. N-Phthaloyl-β-alanine can be coupled to OVA using the mixed anhydride method. N-Phthaloyl-β-alanine has more heterologies .
Cat. No.: HY-168220
CAS No.: 3042887-97-5
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FX-171-C is a noncompetitive Deubiquitinase inhibitor with an IC50 of 1.4 µM .
Cat. No.: HY-RS04624
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F10 Human Pre-designed siRNA Set A contains three designed siRNAs for F10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
