1. Metabolic Enzyme/Protease
  2. Lactate Dehydrogenase
  3. FX-11

FX-11 (Synonyms: LDHA Inhibitor FX11)

Cat. No.: HY-16214 Purity: 98.11%
Handling Instructions

FX-11 is a potent LDH-A inhibitor with an IC50 of 23.3 μM for HeLa cell,a Ki value of 8 μM.

For research use only. We do not sell to patients.

FX-11 Chemical Structure

FX-11 Chemical Structure

CAS No. : 213971-34-7

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 495 In-stock
Estimated Time of Arrival: December 31
5 mg USD 450 In-stock
Estimated Time of Arrival: December 31
10 mg USD 750 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2250 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3350 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

FX-11 is a potent LDH-A inhibitor with an IC50 of 23.3 μM for HeLa cell,a Ki value of 8 μM.

IC50 & Target

IC50: 23.3 μM (LDH-A, HeLa cell) [1].

Molecular Weight

350.41

Formula

C₂₂H₂₂O₄

CAS No.

213971-34-7

SMILES

O=C(C1=C2C=C(CC3=CC=CC=C3)C(C)=CC2=C(CCC)C(O)=C1O)O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (713.45 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8538 mL 14.2690 mL 28.5380 mL
5 mM 0.5708 mL 2.8538 mL 5.7076 mL
10 mM 0.2854 mL 1.4269 mL 2.8538 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.94 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.94 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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FX-11
Cat. No.:
HY-16214
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