14 Results for "

FXI

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "FXI" in MCE Product Catalog:

Cat. No.: HY-P99415
CAS No.: 2098724-83-3
Synonyms: MAA868

Target:  

Factor Xa

Research Areas:  

Cardiovascular Disease

Abelacimab (MAA868) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab can be used in thromboembolic disease studies .
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Cat. No.: HY-P99794
CAS No.: 2056878-75-0
Synonyms: BAY 1213790

Target:  

Factor Xa

Research Areas:  

Cardiovascular Disease

Osocimab (BAY 1213790), an anti-FXIa antibody (Ki=2.4 nM; EC50=0.2 nM). FXI inhibition may reduce the risk of thrombosis. Osocimab inhibits thrombin generation, and prolongs activated partial thromboplastin time. Osocimab exhibits anticoagulant effects .
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Cat. No.: HY-134005
CAS No.: 1223657-78-0
Synonyms: FXI-ASO; BAY2306001; IONIS-FXIRx
Target:  

Factor XI

Research Areas:  

Cardiovascular Disease

ISIS 416858, a single-stranded antisense oligodeoxynucleotide, is a potent and selective inhibitor of FXI mRNA expression.
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Cat. No.: HY-175735
CAS No.: 2563884-39-7
Target:  

Factor XI

Research Areas:  

Cardiovascular Disease

Factor XI-IN-2 is a Factor XI activation inhibitor with an IC50 of 20 nM. Factor XI-IN-2 does not directly inhibit the enzymatic activity of FXIa, but specifically binds to the FXI enzyme precursor and allosterically inhibits the process by which it is activated by FXIIa. Factor XI-IN-2 inhibits thrombosis in the rabbit arteriovenous (AV) shunt thrombosis model. Factor XI-IN-2 can be used for the study of antithrombus .
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Cat. No.: HY-P4331
CAS No.: 113865-85-3
Research Areas:  

Cardiovascular Disease

Boc-Gln-Gly-Arg-AMC is a fluorogenic substrate for kallikrein (PKa), coagulation factor XIIa (FXIIa) and coagulation factor XIa (FXIa). Boc-Gln-Gly-Arg-AMC enables fluorescence-based activity assays for PKa, FXIIa and FXIa .
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Cat. No.: HY-P991581
CAS No.: 2812480-88-7

Target:  

Factor XI

Research Areas:  

Cardiovascular Disease

MK-2060 is a humanized monoclonal antibody inhibitor targeting FXI. MK-2060 can be used for atherothrombosis and venous thromboembolism research .
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Fesomersen sodium
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DNA, d([2′-O-(2-methoxyethyl)]rA-sp-[2′-O-(2-methoxyethyl)]m5rC-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]m5rC-A-sp-T-sp-T-sp-G-sp-G-sp-T-sp-G-sp-m5C-sp-A-sp-m5C-sp-[2′-O-(2-methoxyethyl)]rA-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]m5rU-sp-[2′-O-(2-methoxyethyl)]m5rU-sp-[2′-O-(2-methoxyethyl)]m5rU), 5′-[26-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[6-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]hexyl]amino]-3-oxopropoxy]methyl]-8,12,19-trioxo-16-oxa-7,13,20-triazahexacos-1-yl hydrogen phosphate], sodium salt (1:20)
Cat. No.: HY-139788A
CAS No.: 2380288-85-5
Purity:  98.67%
Synonyms: ION-957943; BAY-2976217; IONIS-FXI-LRx sodium
Fesomersen (sodium) is an antisense oligonucleotide designed to inhibit the production of Factor XI.
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Cat. No.: HY-P991006
CAS No.: 2857858-76-3
Synonyms: KN-060

Target:  

Factor Xa

Research Areas:  

Inflammation/Immunology

HY-P991006 is an FXI/PTA-targeting VH-VH-G1(h-CH2-CH3) dimer type bispecific antibody .
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Cat. No.: HY-RS17241
Research Areas:  

Others

F11 Mouse Pre-designed siRNA Set A contains three designed siRNAs for F11 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Fesomersen
0 Images
DNA, d([2′-O-(2-methoxyethyl)]rA-sp-[2′-O-(2-methoxyethyl)]m5rC-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]m5rC-A-sp-T-sp-T-sp-G-sp-G-sp-T-sp-G-sp-m5C-sp-A-sp-m5C-sp-[2′-O-(2-methoxyethyl)]rA-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]m5rU-sp-[2′-O-(2-methoxyethyl)]m5rU-sp-[2′-O-(2-methoxyethyl)]m5rU), 5′-[26-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[6-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]hexyl]amino]-3-oxopropoxy]methyl]-8,12,19-trioxo-16-oxa-7,13,20-triazahexacos-1-yl hydrogen phosphate]
Cat. No.: HY-139788
CAS No.: 2380135-03-3
Synonyms: ION-957943 free acid; BAY-3563450; IONIS-FXI-LRx
Fesomersen is an antisense oligonucleotide designed to inhibit the production of Factor XI.
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Cat. No.: HY-P700978
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FXI; PTA; F11; Coagulation factor XI
Species:  
Source:  
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Cat. No.: HY-P703948
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Coagulation factor XI; FXI; PTA; F11
Species:  
Source:  
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Cat. No.: HY-P73046
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Coagulation factor XI; Coagulation factor XIa light chain; PTA; FXI; F11
Species:  
Source:  
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Cat. No.: HY-RS04625
Research Areas:  

Others

F11 Human Pre-designed siRNA Set A contains three designed siRNAs for F11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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