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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
Factor XIIa
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "Factor XIIa" in MCE Product Catalog:
Cat. No.: HY-P4331
CAS No.: 113865-85-3
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Cat. No.: HY-149397
CAS No.: 3052551-17-1
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FXIIa-IN-1-IN-2 (Compound 21) is a Factor XIIa inhibitor (Ki app: 62.2 nM). FXIIa-IN-1-IN-2 can be used for research of thrombosis .
Cat. No.: HY-149396A
CAS No.: 3052551-20-6
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FXIIa-IN-1 hydrochloride is the hydrochloride of FXIIa-IN-1 (HY-149396). FXIIa-IN-1 (Compound 22) is a Factor XIIa inhibitor (Ki app: 97.8 nM). FXIIa-IN-1 can be used for research of thrombosis .
Cat. No.: HY-149396
CAS No.: 3052551-19-3
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XIIa-IN-1-IN-3 (Compound 22) is a Factor XIIa inhibitor (Ki app: 97.8 nM). XIIa-IN-1-IN-3 can be used for research of thrombosis .
Cat. No.: HY-P4333
CAS No.: 73554-94-6
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Cat. No.: HY-163347
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FXIIa-IN-3 (Compound 8) is a potent and selective Factor XIIa (FXIIa) inhibitor, with an IC50 of 0.045 μM. FXIIa-IN-3 also exhibits a substantial margin of selectivity against related serine proteases, including FXIa, FXa, and FIXa. FXIIa-IN-3 can be used for the research of thromboembolic diseases .
Cat. No.: HY-162646
CAS No.: 3047411-80-0
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FXIIa-IN-5 (Compound 4J) is an orally active, selective inhibitor for factor XIIa (FXIIa), with IC50 of 21 nM. FXIIa-IN-5 inhibits the intrinsic coagulation pathways, and exhibits anti-inflammatory and antithrombotic activity in Carrageenan (HY-125474)-induced mice thrombosis models. FXIIa-IN-5 exhibits moderate pharmacokinetic characteristics and slightly toxicity (at 100 mg/kg) .
Cat. No.: HY-184008
CAS No.: 3107571-66-1
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FXIIa-IN-6 is a potent, selective, and irreversible covalent inhibitor of Factor XIIa (FXIIa) with an IC50 of 2 nM. FXIIa-IN-6 exhibits ≥2,500-fold selectivity over related serine proteases. FXIIa-IN-6 exhibits favorable anticoagulant and anti-inflammatory activities and can be used in sepsis research .
Cat. No.: HY-P700599
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: F12 Coagulation Factor XII; EC 3.4.21.38; Hageman Factor; HAF; Coagulation Factor XIIa heavy chain; Coagulation Factor XIIa light chain
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
