32 Results for "

GDF15

" in MedChemExpress (MCE) Product Catalog:
Products (32)

32 Results for "GDF15" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99241
CAS No.: 2368950-15-4
Synonyms: PF 06946860

Research Areas:  

Cancer

Ponsegromab is a Growth differentiation factor 15 (GDF15) inhibitor with human, cynomolgus monkey, and mouse target IC50 values of 0.123 nM, 0.053 nM, and 0.102 nM, respectively . Ponsegromab acts as a chemosensitizer, increases intracellular reactive oxygen species, reduces glutathione levels . Ponsegromab can be used for the research of oxaliplatin-resistant colorectal cancer .
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3
3 Cited Publications
Cat. No.: HY-P77945
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta
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2
2 Cited Publications
Cat. No.: HY-P99100
CAS No.: 2556646-63-8
Synonyms: CTL-002

Research Areas:  

Cancer

Visugromab (CTL-002) is a GDF-15 neutralizing IgG4 mAb. Visugromab has synergistic anticancer activity with the anti-PD1 antibody Nivolumab (HY-P9903) and can effectively act on PD-1/PD-L1 relapsed/refractory metastatic solid tumors. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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2
2 Cited Publications
Cat. No.: HY-P75170
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Growth/differentiation factor 15; MIC-1; NAG-1; NRG-1; PTGFB
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1
1 Cited Publications
Cat. No.: HY-P75171
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Growth/differentiation factor 15; MIC-1; NAG-1; NRG-1; PTGFB
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Cat. No.: HY-W587486
CAS No.: 19213-70-8
N‑acetyltaurine is an orally active endogenous sulfonate that is synthesized from taurine and acetate in the renal cortex. N‑acetyltaurine supports bacterial growth as a sole fixed nitrogen or carbon source. N‑acetyltaurine buffers acetyl moieties of mitochondrial acetyl‑CoA in skeletal muscle. N‑acetyltaurine reduces food intake and body weight in obese and lean wild‑type mice in a GFRAL‑dependent manner. N‑acetyltaurine can be used for the research of diet‑induced obesity, hyperacetatemia and diabetes .
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Cat. No.: HY-P990635

Target:  

TGF-β Receptor

Research Areas:  

Cancer

NGM-120 is a fully humanized IgG1 monoclonal antibody targeting GFRAL, which functions by blocking the GDF15-GFRAL axis. NGM-120 reduces serum GDF15 levels, increases body weight, expands central memory and proliferative CD8 + T cell populations, and decreases immunosuppressive and naive regulatory T cell populations. NGM-120 can be used for research on advanced prostate cancer .
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Cat. No.: HY-149406
CAS No.: 431920-24-0
Purity:  99.68%
Target:  

AMPK TGF-β Receptor

Research Areas:  

Cancer

AMPK activator 12 (compound 21) is a potent AMPK activator and GDF15 inducer. AMPK activator 12 increases GDF15 protein levels in human hepatic cells .
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Cat. No.: HY-RS16542
Research Areas:  

Others

Gdf15 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gdf15 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991190
CAS No.: 2894138-72-6
Synonyms: AV-380

Research Areas:  

Cancer

Rilogrotug (AV-380) is a humanized IgG1 monoclonal antibody targeting GDF15 .
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Cat. No.: HY-RS05352
Research Areas:  

Others

GDF15 Human Pre-designed siRNA Set A contains three designed siRNAs for GDF15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS22974
Research Areas:  

Others

Gdf15 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gdf15 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P99100A
CAS No.: 2556646-63-8
Synonyms: CLT-002 (Powder)

Research Areas:  

Cancer

Visugromab (CTL-002) (Powder) is a GDF-15 neutralizing IgG4 mAb. Visugromab (Powder) has synergistic anticancer activity with the anti-PD1 antibody Nivolumab (HY-P9903) and can effectively act on PD-1/PD-L1 relapsed/refractory metastatic solid tumors. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P703935
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta
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Cat. No.: HY-P77945A
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta
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Cat. No.: HY-P77681
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta
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Cat. No.: HY-P700293
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Growth Differentiation Factor 15; Macrophage inhibitory cytokine 1; GDF-15; MIC-1; NAG-1; PLAB; PTGFB; GDF15; Sbf
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Cat. No.: HY-P77682
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta
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Cat. No.: HY-P77946
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta
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Cat. No.: HY-P700726
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta; Placental TGF-β; PTGF-β; PTGFBPTGF-β
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