20 Results for "

GPRC5D

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "GPRC5D" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99394
CAS No.: 2226212-40-2
Synonyms: JNJ-64407564

Target:  

CD3

Research Areas:  

Cancer

Talquetamab (JNJ-64407564) is a humanized bispecific antibody that binds to GPRC5D (member of G protein-coupled receptor family C5 group D) and CD3 to induce T cell-mediated killing of GPRC5D-expressing MM cells through T cell recruitment and activation. Talquetamab (JNJ-64407564) has antitumor activity .
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Cat. No.: HY-P991155
CAS No.: 2988886-91-3
Synonyms: JNJ-79635322; JNJ-5322

Target:  

CD3 TNF Receptor

Research Areas:  

Cancer

Ramantamig (JNJ-79635322) is a humanized monoclonal antibody targeting human CD3ε, GPRC5D, and TNFRSF17 (BCMA). Ramantamig binds to BCMA and GPRC5D on multiple myeloma cells, binds to CD3ε on T cells, forms immunological synapses, and enables T-cell-mediated cytotoxicity. Ramantamig activates T cells concomitantly with inducing myeloma cell cytotoxicity, with no nonspecific T-cell activation in the absence of target myeloma cells. Ramantamig carries mutations to reduce interaction with Fc receptors and disrupt protein A binding of monomeric and homodimerized chains. Ramantamig can be used for the research of multiple myeloma .
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Cat. No.: HY-P991197
Synonyms: LM-305 antibody; AZD-0305 antibody

Target:  

CD3

Research Areas:  

Cancer

Anti-GPRC5D Antibody (LM-305 antibody) is a humanized IgG1 monoclonal antibody that targets GPRC5D. Anti-GPRC5D Antibody is the antibody part of the ADC molecule LM-305. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P991055
CAS No.: 2649379-96-2
Synonyms: RG-6234; RO-7425781

Target:  

CD3

Research Areas:  

Inflammation/Immunology

Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-171754
Research Areas:  

Cancer

LM-305 is an anti-G protein-coupled receptor class 5 member D (GPRC5D) antibody-drug conjugate (ADC). LM-305 consists of Anti-GPRC5D Antibody (HY-P991197) and VcMMAE (HY-15575). LM-305 exhibits potent cytotoxicity against multiple myeloma cells (NCI-H929 and MM.1R) with IC50 values ranging from 0.1 to 0.3 nM. LM-305 can be used in the study of GPRC5D-related relapsed and refractory multiple myeloma (RRMM) .
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Cat. No.: HY-RS05752
Research Areas:  

Others

GPRC5D Human Pre-designed siRNA Set A contains three designed siRNAs for GPRC5D gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17133
Research Areas:  

Others

Gprc5d Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gprc5d gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23579
Research Areas:  

Others

Gprc5d Rat Pre-designed siRNA Set A contains three designed siRNAs for Gprc5d gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991726
CAS No.: 3035714-52-1

Target:  

Orphan GPCR

Research Areas:  

Cancer

Vemzatatug is a humanized IgG1κ monoclonal antibody inhibitor targeting GPRC5D. Vemzatatug has an antitumor activity. Vemzatatug can be used for cancers like multiple myeloma (MM) research .
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Cat. No.: HY-P991587

Target:  

Orphan GPCR

Research Areas:  

Cancer

SAR-446523 is a humanized IgG1 monoclonal antibody inhibitor targeting GPRC5D. SAR-446523 significantly induces antibody-dependent cell-mediated cytotoxicity (ADCC). SAR-446523 has potent antitumor activity with improvement of mouse survival in NK humanized NOG huIL15 transgenic mice model bearing MM cells. SAR-446523 can be used for multiple myeloma (MM) research .
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Cat. No.: HY-P81701
Synonyms: GPRC5D

Host:  

Rabbit

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P77958
Purity:  ≥ 95%, as determined by HPLC.
Synonyms: GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor
Species:  
Source:  
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Cat. No.: HY-P700731
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor
Species:  
Source:  
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Cat. No.: HY-P700998
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor
Species:  
Source:  
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Cat. No.: HY-P77959
Purity:  ≥ 95%, as determined by HPLC.
Synonyms: GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor
Species:  
Source:  
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Cat. No.: HY-P704647
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor
Species:  
Source:  
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Cat. No.: HY-P705025
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor
Species:  
Source:  
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Cat. No.: HY-P811151
Synonyms: G-protein coupled receptor family C group 5 member D, GPRC5D

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P704649
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GPRC5D; G protein-coupled receptor, family C, group 5, member D; G-protein coupled receptor family C group 5 member D; orphan G-protein coupled receptor; MGC129713; MGC129714;
Species:  
Source:  
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Cat. No.: HY-P700457
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: GPRC5D; G protein-coupled receptor, family C, group 5, member D; G-protein coupled receptor family C group 5 member D; orphan G-protein coupled receptor; MGC129713; MGC129714;
Species:  
Source:  
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