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SAR-446523

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SAR-446523 is a humanized IgG1 monoclonal antibody inhibitor targeting GPRC5D. SAR-446523 significantly induces antibody-dependent cell-mediated cytotoxicity (ADCC). SAR-446523 has potent antitumor activity with improvement of mouse survival in NK humanized NOG huIL15 transgenic mice model bearing MM cells. SAR-446523 can be used for multiple myeloma (MM) research.

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  • Pureté : 99.76%
  • Masse moléculaire:144.39 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for SAR-446523
  • SAR-446523 Chemical Structure
    SAR-446523 Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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SAR-446523 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Immobilized Human GPRC5D Protein-VLP can bind SAR-446523. The ED50 for this effect is 37.8 ng/mL.

  • SAR-446523 Chemical Structure
    1/16
  • SAR-446523
  • Immobilized Human GPRC5D Protein-VLP can bind SAR-446523. The ED50 for this effect is 37.8 ng/mL.