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Results for "

Glycolysis inhibition

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6940

    Progenin III

    Apoptosis Cancer
    Prosapogenin A, a natural product from Veratrum, induces apoptosis in human cancer cells in vitro via inhibition of the STAT3 signaling pathway and glycolysis .
    Prosapogenin A
  • HY-D0849

    Iodoacetic acid sodium salt

    Biochemical Assay Reagents Others Neurological Disease
    Sodium iodoacetate is a specific inhibitor of GAPDH. Sodium iodoacetate can induce articular cartilage damage (OA) ) .
    Sodium iodoacetate
  • HY-N0822
    Shikonin
    30+ Cited Publications

    C.I. 75535; Isoarnebin 4

    Chloride Channel Pyruvate Kinase NF-κB TNF Receptor HIV AIM2 Cancer
    Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM . Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway . Shikonin decreases exosome secretion through the inhibition of glycolysis . Shikonin inhibits AIM2 inflammasome activation .
    Shikonin
  • HY-121275

    Pyruvate Kinase Cancer
    Benserazide is a PKM2 inhibitor. Benserazide directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide can be used for the research of melanoma .
    Benserazide

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