305-53-3
305-53-3
Chemical Structure
Sodium iodoacetate
Synonym(s): Iodoacetic acid sodium salt
- CAS No.: 305-53-3
- Formula:C2H2INaO2
- Molecular Weight:207.93
IUPAC Name: sodium 2-iodoacetate
InChIKey: AGDSCTQQXMDDCV-UHFFFAOYSA-M
SMILES: O=C(O[Na])CI
Biological Activity: Sodium iodoacetate is a specific inhibitor of GAPDH and has glycolysis inhibitory activity. In addition, sodium iodoacetate can induce osteoarthritis and related pain models in experimental animals[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sodium iodoacetate | 99.95% | Sodium iodoacetate is a specific inhibitor of GAPDH and has glycolysis inhibitory activity. In addition, sodium iodoacetate can induce osteoarthritis and related pain models in experimental animals. | ||||||||||||||||||||
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References
- [1]. Xu, Y. et al. Glycolysis in Innate Immune Cells Contributes to Autoimmunity. Frontiers in Immunology, 13. [Content Brief]
- [2]. Na, H. et al. Soluble CCR2 gene therapy controls joint inflammation, cartilage damage, and the progression of osteoarthritis by targeting MCP-1 in a monosodium iodoacetate (MIA)-induced OA rat model. Journal of Translational Medicine, 20(1) [Content Brief]
- [3]. Kobayashi K, et al. Sodium iodoacetate-induced experimental osteoarthritis and associated pain model in rats[J]. Journal of Veterinary Medical Science, 2003, 65(11): 1195-1199. [Content Brief]
- [4]. Güler N, et al. Sodium iodoacetate induced osteoarthrosis model in rabbit temporomandibular joint: CT and histological study (part I)[J]. International journal of oral and maxillofacial surgery, 2011, 40(11): 1289-1295. [Content Brief]
