39 Results for "

Herpes simplex virus type 1

" in MedChemExpress (MCE) Product Catalog:
Products (39)

39 Results for "Herpes simplex virus type 1" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-15303
CAS No.: 348086-71-5
Purity:  99.94%
Synonyms: AIC316; BAY 57-1293
Target:  

DNA/RNA Synthesis HSV

Research Areas:  

Infection

Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
loading...
    loading...
7
7 Publications Verification
Cat. No.: HY-15303A
CAS No.: 1428333-96-3
Purity:  99.51%
Synonyms: AIC316 mesylate; BAY 57-1293 mesylate
Target:  

DNA/RNA Synthesis HSV

Research Areas:  

Infection

Pritelivir mesylate (BAY 57-1293 mesylate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
loading...
    loading...
7
7 Publications Verification
Cat. No.: HY-15303B
CAS No.: 1428321-10-1
Purity:  99.51%
Synonyms: AIC316 mesylate hydrate; BAY 57-1293 mesylate hydrate
Target:  

DNA/RNA Synthesis HSV

Research Areas:  

Infection

Pritelivir mesylate hydrate (BAY 57-1293 mesylate hydrate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate hydrate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-N0772
CAS No.: 24699-16-9
Isomangiferin is an orally active xanthone C-glucoside, and its chemical structure is similar to Mangiferin (HY-N0290). Isomangiferin is an effective VEGFR-2 kinase inhibitor, which can induces cell apoptosis, inhibit the growth, metastasis and angiogenesis of breast cancer. Isomangiferin exerts anti-inflammatory effects by inhibiting the HMGB1/NLRP3/NF-κB signaling pathway, thereby improving the renal function indicators of diabetic mice. Isomangiferin exhibits inhibitory effects on various bacteria and herpes simplex virus type 1 (HSV-1). Isomangiferin promotes the migration and osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and reduces cell apoptosis and the production of ROS by activating the AMPK/ACC pathway, thereby facilitating fracture healing .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N2004
CAS No.: 124-76-5
Synonyms: (±)-Isoborneol
Isoborneol ((±)-Isoborneol) is a monoterpenoid alcohol present in the essential oils of numerous medicinal plants and has antioxidant and antiviral properties. Isoborneol is a potent inhibitor of herpes simplex virus type 1 (HSV-1) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-U00124B
CAS No.: 41544-24-5
Target:  

HSV

Research Areas:  

Infection

Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P70494
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NECTIN1; OFC7; Prev. PVRL1; Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C); Prev. HVEC; Herpesvirus Ig-Like Receptor; Prev. ED4; Ectodermal Dysplasia 4 (Margarita Island type); Nectin-1; Herpes simplex virus type 1 Sensitivity; PRR1; Herpesv
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-160222
Target:  

HSV STING IFNAR NF-κB

Research Areas:  

Infection

HSV-60mer sodium is a 60 bp double-stranded DNA oligonucleotide derived from the HSV-1 genome, and also an IFNβ inducer. HSV-60mer sodium colocalizes with endogenous cytoplasmic IFI16 in immune cells. HSV-60mer sodium activates the transcription factors IRF3 and NF-κB, induces the production of proinflammatory cytokines, and inhibits HSV-1 replication in immune cells. HSV-60mer sodium can be used in studies related to herpes simplex virus type 1 infection .
loading...
    loading...
Cat. No.: HY-N1060
CAS No.: 40456-50-6
Yatein is a lignan isolated from A. chilensis, with antiproliferative activity . Yatein suppresses herpes simplex virus type 1 (HSV-1 ) replication by interruption the immediate-early gene expression .
loading...
    loading...
Cat. No.: HY-N3395
CAS No.: 152464-78-3
Leachianone G is an antiviral flavonoid from the root bark of Morus alba L. Leachianone G shows potent antiviral activity against herpes simplex type 1 virus (HSV-1) with an IC50 value of 1.6 μg/mL .
loading...
    loading...
Cat. No.: HY-131944
CAS No.: 3054-47-5
Purity:  ≥96.0%
Target:  

Apoptosis HSV

S-Acetylglutathione is a glutathione derivative and intracellular glutathione supplement that bypasses glutathione synthetase deficiency through intracellular thioesterase conversion, exhibits higher blood stability than glutathione, and selectively induces apoptosis in lymphoma and malignant cells by inducing oxidative stress (apoptosis). S-Acetylglutathione can be used in research on glutathione synthetase deficiency, herpes simplex virus type 1 infection, murine AIDS, lymphoma, and malignant tumors .
loading...
    loading...
Cat. No.: HY-W002008
CAS No.: 480-68-2
Target:  

HSV

Research Areas:  

Infection Inflammation/Immunology

5-Nitrobarbituric acid is a herpes simplex virus type-1 (HSV-1) inhibitor (IC50=1.7 μM) .
loading...
    loading...
Cat. No.: HY-P10868
CAS No.: 2056232-82-5
Synonyms: RLS-0071
Pegtarazimod (RLS-0071) is a dual-target anti-inflammatory peptide that exerts its effects by simultaneously regulating the complement system and neutrophil-associated inflammatory pathways. Pegtarazimod reduces ROS production both in vitro and in vivo, and decreases the level of neutrophil elastase, a marker of neutrophil extracellular traps (NETs), in vivo, thereby alleviating inflammatory responses. Pegtarazimod significantly improves the survival rate of mice in multiple in vivo models of acute graft-versus-host disease (aGVHD). Pegtarazimod inhibits the activation of the C1 complex, reduces the herpes zoster-like spread of herpes simplex virus type 1 skin infection, and improves the survival rate of infected mice . Pegtarazimod can be used in research related to acute graft-versus-host disease, acute pulmonary diseases, and skin herpes simplex virus type 1 infection .
loading...
    loading...
Cat. No.: HY-U00224
CAS No.: 114778-60-8
Target:  

EBV VZV HSV

Research Areas:  

Infection

BRL44385 is a potent and selective inhibitor of the replication of herpes simplex virus types 1 and 2 (HSV-1 and HSV2), varicella zoster virus (VZV) and Epstein-Barr virus (EBV).
loading...
    loading...
Cat. No.: HY-U00124
CAS No.: 53783-83-8
Target:  

HSV

Research Areas:  

Infection

Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication .
loading...
    loading...
Cat. No.: HY-123211
CAS No.: 273388-09-3
Target:  

HSV

Research Areas:  

Infection

WAY-150138 inhibits replication of herpes simplex virus type 1 (HSV-1) that acts by preventing the incorporation of DNA-packaging proteins into capsids as they are assembled
loading...
    loading...
Cat. No.: HY-177638
CAS No.: 141442-28-6
Target:  

HSV

Research Areas:  

Infection

ISIS 1082 is an antisense oligonucleotide targeted to the translation initiation codon of herpes simplex virus (HSV) type 1 and 2 virion capsid protein. It has been shown to inhibit HSV-1 replication in vitro
loading...
    loading...
Cat. No.: HY-15303AR
CAS No.: 1428333-96-3
Synonyms: AIC316 mesylate (Standard); BAY 57-1293 mesylate (Standard)
Target:  

HSV Reference Standards

Research Areas:  

Infection

Pritelivir (mesylate) (Standard) is the analytical standard of Pritelivir (mesylate). This product is intended for research and analytical applications. Pritelivir mesylate (BAY 57-1293 mesylate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
loading...
    loading...
Cat. No.: HY-15303R
CAS No.: 348086-71-5
Synonyms: AIC316 (Standard); BAY 57-1293 (Standard)
Target:  

HSV Reference Standards

Research Areas:  

Infection

Pritelivir (Standard) is the analytical standard of Pritelivir. This product is intended for research and analytical applications. Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
loading...
    loading...
Cat. No.: HY-N14564
CAS No.: 142382-46-5
Cycloviracin B2 is an antibiotic with antiviral activity. Cycloviracin B2 has a strong inhibitory activity against herpes simplex virus type 1 (HSV-1) .
loading...
    loading...