9 Results for "

Higenamine

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Higenamine" in MCE Product Catalog:

10
Higenamine
Higenamine
0 Images
10 Publications Verification
Cat. No.: HY-N2037
CAS No.: 5843-65-2
Synonyms: Norcoclaurine; Demethyl-Coclaurine
Category:  

Alkaloids Ranunculaceae Phenols Polyphenols  Aconitum carmichaeli Debx. Plants Disease Research Fields Isoquinoline Alkaloids Endocrinology

Target:  

MAP3K MDM-2/p53 Adrenergic Receptor ROS Kinase Apoptosis

Higenamine (Norcoclaurine), a β2-AR agonist with antioxidant capability, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine is also a α1-adrenergic receptor antagonist with hypotensive effect. is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine protects myocyte Apoptosis and ischemia/reperfusion (I/R) injury through selective activation of beta2-adrenergic receptor (β2-AR). Higenamine also reduces I/R-induced myocardial infarction in mice. Higenamine can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine can be used to study cancer, inflammation, cardiorenal syndrome and other diseases .
loading...
    loading...
View All Sizes
10
Higenamine hydrochloride
Higenamine hydrochloride
0 Images
10 Publications Verification
Cat. No.: HY-N2037A
CAS No.: 11041-94-4
Synonyms: Norcoclaurine hydrochloride
Category:  

Plants Lindera aggregata (Sims) Kosterm. Alkaloids Phenols Polyphenols Lauraceae Disease Research Fields Isoquinoline Alkaloids Endocrinology Cancer

Target:  

MAP3K MDM-2/p53 ROS Kinase Apoptosis

Higenamine hydrochloride is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases .
loading...
    loading...
View All Sizes
1
(S)-Higenamine hydrobromide
(S)-Higenamine hydrobromide
0 Images
1 Cited Publications
Cat. No.: HY-N2037C
CAS No.: 105990-27-0
Synonyms: (S)-Norcoclaurine hydrobromide
Category:  

Alkaloids Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields Isoquinoline Alkaloids

Target:  

Endogenous Metabolite

(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) .
loading...
    loading...
View All Sizes
(S)-Higenamine
(S)-Higenamine
0 Images
Cat. No.: HY-N2037B
CAS No.: 22672-77-1
Synonyms: (S)-Norcoclaurine
Category:  

Alkaloids Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields Isoquinoline Alkaloids

Target:  

Endogenous Metabolite

(S)-Higenamine ((S)-Norcoclaurine), a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) .
loading...
    loading...
View All Sizes
Higenamine-d4 hydrochloride
Higenamine-d4 hydrochloride
0 Images
Cat. No.: HY-N2037AS
CAS No.: 2249814-84-2
Synonyms: Norcoclaurine-d4 hydrochloride; Demethyl-Coclaurine-d4 hydrochloride
Higenamine-d4 (Norcoclaurine-d4; Demethyl-Coclaurine-d4) hydrochloride is deuterium-labeled Higenamine (hydrochloride) (HY-N2037A) .
loading...
    loading...
View All Sizes
Higenamine (Standard)
Higenamine (Standard)
0 Images
Cat. No.: HY-N2037R
CAS No.: 5843-65-2
Synonyms: Norcoclaurine (Standard); Demethyl-Coclaurine (Standard)
Category:  

Alkaloids Ranunculaceae Phenols Polyphenols  Aconitum carmichaeli Debx. Plants Isoquinoline Alkaloids

Target:  

Reference Standards MAP3K MDM-2/p53 Adrenergic Receptor ROS Kinase Apoptosis

Higenamine (Norcoclaurine), a β2-AR agonist with antioxidant capability, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine is also a α1-adrenergic receptor antagonist with hypotensive effect. is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine protects myocyte Apoptosis and ischemia/reperfusion (I/R) injury through selective activation of beta2-adrenergic receptor (β2-AR). Higenamine also reduces I/R-induced myocardial infarction in mice. Higenamine can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine can be used to study cancer, inflammation, cardiorenal syndrome and other diseases .
loading...
    loading...
View All Sizes
Higenamine hydrochloride (Standard)
Higenamine hydrochloride (Standard)
0 Images
Cat. No.: HY-N2037AR
CAS No.: 11041-94-4
Synonyms: Norcoclaurine hydrochloride (Standard)
Category:  

Alkaloids Phenols Polyphenols Plants Lauraceae Isoquinoline Alkaloids Lindera aggregata (Sims) Kosterm.

Target:  

MAP3K Reference Standards MDM-2/p53 ROS Kinase Apoptosis

Higenamine (hydrochloride) (Standard) is the analytical standard of Higenamine (hydrochloride). This product is intended for research and analytical applications. Higenamine hydrochloride is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases .
loading...
    loading...
View All Sizes
Higenamine-d4-1 hydrochloride
Higenamine-d4-1 hydrochloride
0 Images
Cat. No.: HY-N2037AS1
Synonyms: Norcoclaurine-d4-1 hydrochloride; Demethyl-Coclaurine-d4-1 hydrochloride
Higenamine-d4-1 (Norcoclaurine-d4-1) hydrochloride is deuterium labeled Higenamine (hydrochloride). Higenamine hydrochloride is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases .
loading...
    loading...
View All Sizes
(S)-Higenamine 4'-O-beta-D-glucoside
(S)-Higenamine 4'-O-beta-D-glucoside
0 Images
Cat. No.: HY-N21517
CAS No.: 1440545-91-4
Synonyms: (S)-Norcocalurine 4′-O-glucoside
Category:  

Alkaloids Plants Isoquinoline Alkaloids Nymphaeaceae Plumula nelumbinis

loading...
    loading...
View All Sizes
Assay Types