8 Results for "

IGHE

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "IGHE" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99300
CAS No.: 1322627-61-1
Synonyms: QGE 031; Anti-IGHE Recombinant Antibody

Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

Ligelizumab (QGE 031) is a humanized high-affinity anti-immunoglobulin IgE monoclonal antibody. Ligelizumab selectively inhibits the binding of IgE to the high-affinity receptor FcεRI, while the inhibitory effect on the low-affinity receptor CD23 is weak. Ligelizumab can inhibit the activation of effector cells such as mast cells and Basophil, while reducing the production of IgE by B cells, and restoring the IFN-α production and regulatory T cell (Treg) induction function of plasmacytoid dendritic cells (pDC). Ligelizumab can be used in the study of allergic diseases (such as chronic spontaneous urticaria, allergic asthma) .
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Cat. No.: HY-P99313
CAS No.: 1228538-47-3
Synonyms: Anti-Human IGHE Recombinant Antibody

Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology

Quilizumab (Anti-Human IGHE Recombinant Antibody) is a humanized IgG1κ monoclonal antibody targeting immunoglobulin epsilon (also konwn as: IGHE, IgE). Quilizumab targets the M1-prime fragment of membrane-expressed IGHE/IgE, leading to IGHE/IgE switching and memory B cell depletion. Quilizumab has potential in asthma research .
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Cat. No.: HY-P991252
Synonyms: AIMab-7195

Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

XmAb-7195 (AIMab-7195) is a human monoclonal antibody (mAb) targeting IGHE. XmAb-7195 can be used in Food hypersensitivity, Allergic asthma, Allergic rhinitis, Atopic dermatitis and Conjunctivitis research .
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Cat. No.: HY-P990936
CAS No.: 2823332-50-7
Synonyms: JYB-1904; RPT904

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

HY-P990936 is an IGHE-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P991256

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

FB-825 is a human monoclonal antibody (mAb) targeting IGHE. FB-825 targets the CεmX domain of membrane IgE (mIgE), resulting in the downregulation of mIgE-positive B cells and the production of IgE. FB-825 can be used in Allergic asthma, Atopic dermatitis, Job syndrome and Allergic rhinitis research .
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Cat. No.: HY-RS19398
Research Areas:  

Others

Ighe Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ighe gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16358
Research Areas:  

Others

IGHE Human Pre-designed siRNA Set A contains three designed siRNAs for IGHE gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P73907
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Immunoglobulin heavy constant epsilon; IGHE; IgE
Species:  
Source:  
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