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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
IS
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "IS" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P7309
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor NecrosIS Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of ApoptosIS; APO3L; Tumor NecrosIS Factor Ligand 4A; Tumor NecrosIS Factor Ligand Superfamily Member 12; HCG1991317, IS
Species:
Human
Source:
CHO
1
1
1 Cited Publications
Cat. No.: HY-148152A
Purity: 98.15%
PSMA I&S TFA is a PSMA-targeted imaging agent. PSMA I&S TFA undergoes PSMA-mediated internalization into PSMA-expressing cells, with uptake into PSMA-positive tissues competitively inhibited by a potent PSMA inhibitor. PSMA I&S TFA can be used for the research of prostate cancer .
Cat. No.: HY-19151
CAS No.: 141283-87-6
Synonyms: IS-741
Target:
Research Areas:
Fuzapladib (IS-741), an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site .
Cat. No.: HY-19151A
CAS No.: 141284-73-3
Synonyms: IS-741 sodium
Target:
Research Areas:
Fuzapladib (IS-741) sodium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib sodium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib sodium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site .
Cat. No.: HY-159147
CAS No.: 2570251-69-1
Target:
Research Areas:
SIAIS039 is an orally active c-ros oncogene 1 (ROS1)-specific PROTAC with DC50s of 154.46 nM, 126.47 nM, 143.69 nM for HCC78 cells, Ba/F3 expressing the CD74-ROS1 fusion and Ba/F3 expressing the SDC4-ROS1 fusion, respectively. SIAIS039 suppresses cell proliferation, induces cell cycle arrest and apoptosis, and inhibits clonogenicity against ROS1-positive cells. SIAIS039 demonstrates anti-tumour effects against ROS1-driven tumor growth vivo. SIAIS039 is composed of the ALK inhibitor Brigatinib (HY-12857), a linker EM-12 (HY-138793), and a VHL ligand E3 ubiquitin ligase 1-Butyne (Red: Brigatinib; Blue: VHL ligand; Black: linker) .
Cat. No.: HY-125807
CAS No.: 324561-95-7
Target:
G Protein-coupled Receptor Kinase (GRK) Apoptosis Reactive Oxygen Species (ROS) Akt p38 MAPK
Research Areas:
IS20 is a Prokineticin receptor 1 (PKR1) agonist. IS20 diminishes Doxorubicin (HY-15142A) mediated apoptosis and ROS production by activating Akt or MAPK pathways. IS20 protects the heart against Doxorubicin-induced cardiovascular toxicity and improves the survival rate and cardiac function in mouse models. IS20 does not alter the cytotoxicity and antitumor activity of acute DOX treatment in breast cancer cells and MDA-MB-231 xenograft mouse models. IS20 can be used for cancers research .
Cat. No.: HY-106124
CAS No.: 133790-13-3
Target:
Research Areas:
IS-159 is a potent serotonin 5-HT1 agonist. IS-159 has the potential for the research of migraine .
Cat. No.: HY-P11019
CAS No.: 3067986-23-3
Target:
Research Areas:
Cat. No.: HY-19151B
CAS No.: 141284-74-4
Synonyms: IS-741 potassium
Target:
Research Areas:
Fuzapladib (IS-741) potassium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib potassium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib potassium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site .
Cat. No.: HY-19151C
CAS No.: 141284-77-7
Synonyms: IS-741 calcium
Target:
Research Areas:
Fuzapladib calcium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib calcium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib calcium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site .
Cat. No.: HY-P703512
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: lysine decarboxylase; Lysine decarboxylase; 232-783-1; DTXSID9093854; Decarboxylase, lysine; EINECS 232-783-1; RefChem:800203; cadA lysine decarboxylase; 9024-76-4
Species:
Others
Source:
E. coli
Cat. No.: HY-P703211
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC6A9; Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 9; Solute Carrier Family 6 Member 9; Transporter; Sodium- And Chloride-Dependent Glycine Transporter 1; GCENSG; GlyT-1; GlyT1; GLYT1; IS6
Species:
Human
Source:
HEK293
Cat. No.: HY-P77263
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor NecrosIS Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of ApoptosIS; APO3L; Tumor NecrosIS Factor Ligand 4A; Tumor NecrosIS Factor Ligand Superfamily Member 12; HCG1991317, IS
Species:
Human
Cynomolgus
Source:
HEK293
Cat. No.: HY-P77264
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor NecrosIS Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of ApoptosIS; APO3L; Tumor NecrosIS Factor Ligand 4A; Tumor NecrosIS Factor Ligand Superfamily Member 12; HCG1991317, IS
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P77265
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor NecrosIS Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of ApoptosIS; APO3L; Tumor NecrosIS Factor Ligand 4A; Tumor NecrosIS Factor Ligand Superfamily Member 12; HCG1991317, IS
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P77266
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor NecrosIS Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of ApoptosIS; APO3L; Tumor NecrosIS Factor Ligand 4A; Tumor NecrosIS Factor Ligand Superfamily Member 12; HCG1991317, IS
Species:
Rat
Source:
HEK293
Cat. No.: HY-P700156AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor NecrosIS Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of ApoptosIS; APO3L; Tumor NecrosIS Factor Ligand 4A; Tumor NecrosIS Factor Ligand Superfamily Member 12; HCG1991317, IS
Species:
Human
Source:
E. coli
Cat. No.: HY-P700229AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF12; TNLG4A; TNF Superfamily Member 12; TNF12; TWEAK; Tumor NecrosIS Factor Superfamily Member 12; DR3LG; TNF-Related WEAK Inducer Of ApoptosIS; APO3L; Tumor NecrosIS Factor Ligand 4A; Tumor NecrosIS Factor Ligand Superfamily Member 12; HCG1991317, IS
Species:
Mouse
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
