2. Search Result
Search Result
Results for "

Integrin-IN-2

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

2

Biochemical Assay Reagents

1

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130119
    Integrin-IN-2

    		Integrin Cancer
    Integrin-IN-2 (compound 39) is an orally bioavailable pan αv integrin inhibitor. Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively .
    Integrin-IN-2
  • HY-175287
    α5β1 integrin agonist-2

    		Integrin Cancer
    α5β1 integrin agonist-2 (Compound 2) is a selective α5β1 integrin agonist (EC50 = 45.98 nM). α5β1 integrin agonist-2 induces integrin activation. α5β1 integrin agonist-2 is applicable to the research of leukemia .
    α5β1 integrin agonist-2
  • HY-173496
    ST6GAL1-IN-1

    		Sialyltransferase Integrin VEGFR Akt Cancer
    ST6GAL1-IN-1 is an orally active selective ST6GAL1 inhibitor (IC50 = 20 μM). ST6GAL1-IN-1 exhibits high antimetastatic potential, effectively inhibiting the migration of MDA-MB-231 cells at noncytotoxic concentrations. ST6GAL1-IN-1 can disrupt integrin sialylation in MDA-MB-231 cells. ST6GAL1-IN-1 inhibits tumor angiogenesis and cancer metastasis via the Integrin/VEGFR2-mediated signaling pathway. ST6GAL1-IN-1 effectively suppresses both tumor growth and cancer metastasis on the MDA-MB-231 xenograft model. ST6GAL1-IN-1 can be used for the study of Triple-negative breast cancer (TNBC) .
    ST6GAL1-IN-1
  • HY-NP132A
    Recombinant humanized type III collagen (MW 55900)

    		Biochemical Assay Reagents Integrin Autophagy Apoptosis Discoidin Domain Receptor Cancer
    Recombinant humanized type III collagen (MW 55900) is a type III collagen with a molecular weight of 55900 Da. Recombinant humanized type III collagen has various biological functions, such as promoting skin extracellular matrix regeneration and improving the cell microenvironment. Recombinant humanized type III collagen inhibits the proliferation, migration, and invasion of breast cancer cells. Type III collagen functions in cell adhesion, migration, proliferation and differentiation through its interaction with integrins .
    Recombinant humanized type III collagen (MW 55900)
  • HY-NP132
    Recombinant Humanized Type III Collagen 28.6kDa

    		Biochemical Assay Reagents Integrin Autophagy Apoptosis Discoidin Domain Receptor Cancer
    Recombinant Humanized Type III Collagen 28.6kDa is a 28.6 kDa recombinant humanized type III collagen. Recombinant Humanized Type III Collagen possesses a variety of biological functions, such as promoting the regeneration of the skin extracellular matrix and improving the cellular microenvironment. Recombinant Humanized Type III Collagen can also inhibit the proliferation, migration and invasion of breast cancer cells. Recombinant Humanized Type III Collagen plays a role in cell adhesion, migration, proliferation and differentiation by interacting with Integrin .
    Recombinant Humanized Type III Collagen 28.6kDa
  • HY-129453
    BOP sodium

    		Integrin Inflammation/Immunology
    BOP sodium is a potent and selective dual α9β1/α4β1 integrin inhibitor with Kd values in the picomolar range. BOP sodium shows the rapid and preferential mobilization of hematopoietic stem cell (HSC) and progenitors. BOP sodium has little inhibitory activity on α4β7, α1β1, α2β1, and α5β1, αIIBβ3 integrins .
    BOP sodium
  • HY-156521
    αvβ1 integrin-IN-2

    		Integrin Others
    αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of integrins ανβ1 and α5β1 with IC50s of 0.9 nM，and 33 nM，respectively. αvβ1 integrin-IN-2 also inhibits other integrins with ，，IC50s of 380 nM (ανβ3)，280 nM (ανβ5)，230 nM (ανβ6)，87 nM (ανβ8)，respectively，in SPRA assay .
    αvβ1 integrin-IN-2
  • HY-153807
    αvβ6 integrin inhibitor 2

    		Integrin Inflammation/Immunology
    αvβ6 integrin inhibitor 2 is a potent ανβ6 integrin inhibitor with an IC50 of 96.5 nM (WO2020081154A1, example 19) .
    αvβ6 integrin inhibitor 2
  • HY-185350
    α4β7 Integrin-IN-2

    		Integrin Inflammation/Immunology
    α4β7 Integrin-IN-2 is an inhibitor of human α4β7 integrin with an IC50 <5 nM. α4β7 Integrin-IN-2 modulates α4β7 integrin-mediated biological pathways. α4β7 Integrin-IN-2 can be used for the research of inflammatory dieases .
    α4β7 Integrin-IN-2
  • HY-P99946
    Erlizumab

    rhuMAb

    		 Integrin Cardiovascular Disease Inflammation/Immunology
    Erlizumab (rhuMAb) is a monoclonal antibody against the Integrin b2/ITGB2/CD18 subunit of the Mac-1 receptor. Erlizumab can reduce reperfusion injury in myocardial infarction .
    Erlizumab
  • HY-185466
    ανβ6 Integrin ligand-2

    		Integrin Inflammation/Immunology
    ανβ6 Integrin ligand-2 is a ανβ6 integrin ligand .
    ανβ6 Integrin ligand-2
  • HY-185468
    Tris-ανβ6 integrin ligand-2

    		Integrin Inflammation/Immunology
    Tris-ανβ6 integrin ligand-2 (the ligand part of Compound 151) is a Tris-ανβ6 integrin ligand .
    Tris-ανβ6 integrin ligand-2

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: