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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
Itaconic acid
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "Itaconic acid" in MCE Product Catalog:
4
Category:
Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
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10 Publications Verification
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IRG1-IN-1 is an itaconic acid derivative. IRG1-IN-1 can inhibit immune-responsive gene 1 (IRG1) activity. IRG1-IN-1 can be used for the research of cancer, inflammation and autoimmune diseases .
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7 Cited Publications
Synonyms: Methylmaleic acid; Citraconate
Cat. No.: HY-Y0520S
CAS No.: 2095777-38-9
Cat. No.: HY-W094214
CAS No.: 7338-27-4
Synonyms: β-Methyl itaconate
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Monomethyl itaconate (β-Methyl itaconate) is a monomethyl ester derivative of Itaconic acid (HY-Y0520). Monomethyl itaconate can copolymerize with PEGMA to form pH-sensitive hydrogels .
Cat. No.: HY-172148
CAS No.: 2641132-66-1
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Itaconic acid prodrug-1 (Compound P2) is an orally active prodrug of Itaconic acid (HY-Y0520) that efficiently delivers the active ingredient Itaconic acid to skin tissue following oral administration. Itaconic acid prodrug-1 possesses immunomodulatory properties, significantly inhibiting Poly(I:C)/IFNγ-induced inflammatory cytokines in human epidermal keratinocytes. Itaconic acid prodrug-1 can be utilized for the research of alopecia areata and other inflammatory skin diseases .
Cat. No.: HY-178915
CAS No.: 2374162-36-2
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ITA-5 is a TBK1 inhibitor based on the structure of itaconic acid. can significantly inhibit the secretion of IFN-β. ITA-5 can inhibit the phosphorylation of TBK1, IRF3, and STAT1. ITA-5 can be used for research on autoimmune diseases and excessive inflammation .
Cat. No.: HY-178916
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ITA-9 is a TBK1 inhibitor based on the structure of itaconic acid. ITA-9 can inhibit the IFN-I signaling pathway. ITA-9 can inhibit the phosphorylation of TBK1, IRF3, and STAT1. ITA-9 can be used for research on inflammatory reactions and tissue damage .
Cat. No.: HY-113298R
CAS No.: 498-23-7
Synonyms: Methylmaleic acid (Standard); Citraconate (Standard)
Cat. No.: HY-W143131S
CAS No.: 2751594-46-2
Synonyms: Itaconic acid Diethyl Ester (stabilized with TBC)-13C5
Cat. No.: HY-185447
CAS No.: 3086566-93-7
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Biotin-itaconate is a biotin-labeled itaconic anhydride that targets PD-L1. Biotin-itaconate acts as a biotin probe for in vitro alkylation assays to identify itaconate-modified protein substrates-typically substrates containing cysteine residues. Biotin-itaconate is applicable to cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
