Itaconic acid (Standard)
Based on 1 Customer Validation
Itaconic acid (Standard) is the analytical standard of Itaconic acid. This product is intended for research and analytical applications. Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect.
For research use only. We do not sell to patients.
- Purity: 99.99%
- CAS No.: 97-65-4
- Formula: C5H6O4
- Molecular Weight:130.10
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 97-65-4
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Appearance Solid
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Molecular Weight 130.10
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Formula C5H6O4
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Color White to off-white
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SMILES
O=C(O)C(CC(O)=O)=C
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Synonyms
Methylenesuccinic acid (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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Handling Instructions (2659 KB)
References
[1]. Weiss JM, et, al. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. J Clin Invest. 2018 Aug 31;128(9):3794-3805. [Content Brief]
[2]. Zhao M, et, al. Itaconic acid production in microorganisms. Biotechnol Lett. 2018 Mar;40(3):455-464. [Content Brief]
[3]. Qu C, et al. Itaconic acid induces ferroptosis by activating ferritinophagy. Biochem Biophys Res Commun. 2021 Oct 25;583:56-62. [Content Brief]
[4]. Zhu X, et al. Itaconic acid exerts anti-inflammatory and antibacterial effects via promoting pentose phosphate pathway to produce ROS. Sci Rep. 2021 Sep 13;11(1):18173. [Content Brief]
[5]. Umbrasas D, et al. Effects of itaconic acid on neuronal viability and brain mitochondrial functions. J Bioenerg Biomembr. 2021 Oct;53(5):499-511. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)