11 Results for "

Kv4.2 channel

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "Kv4.2 channel" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-108588
CAS No.: 426834-69-7
Purity:  99.92%
Target:  

Potassium Channel

Research Areas:  

Cardiovascular Disease

NS5806, a potent potassium current activator, increases KV4.3/KChIP2 peak current amplitudes with an EC50 of 5.3 μM. NS5806 slows KV4.3 and KV4.2 current dacay in channel complexes containing KChIP2 .
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Cat. No.: HY-108574
CAS No.: 478341-55-8
Purity:  99.61%
Research Areas:  

Neurological Disease

CP 339818 hydrochloride is a non-peptide Kv1.3 channel (IC50 = 200 nM) and Kv1.4 channel blocker. CP 339818 hydrochloride inhibits HCN channel with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl -). CP 339818 hydrochloride has significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. CP 339818 hydrochloride selectively blocked Kv1.3, thereby inhibiting the activation process of human T cells. CP 339818 hydrochloride can be used to study the physiological functions of HCN and Kv channels .
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Cat. No.: HY-P2786A
CAS No.: 741738-57-8
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Phrixotoxin 2 is a Kv4 family potassium channel inhibitor, with Ki values in rats of 120 nM for Kv4.2, 110 nM for Kv4.3, and 230 nM for Kv4.1. Phrixotoxin 2 mediates voltage-dependent inhibition of Kv4.2 and Kv4.3 currents, and voltage-independent inhibition of Kv4.1 currents. Phrixotoxin 2 fails to inhibit A-type K + currents in visceral dorsal root ganglion neurons. Phrixotoxin 2 induces contraction of non-pregnant uterine smooth muscle and triggers orofacial cold hyperalgesia in rats. Phrixotoxin 2 can distinguish the contribution of Kv4 subunits to A-type K + currents in different subsets of sensory neurons. Phrixotoxin 2 can be used in research related to chronic pain and trigeminal neuropathic pain .
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Cat. No.: HY-P5155
CAS No.: 741738-59-0
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Stromatoxin 1 is an inhibitor of Potassium Channel, a peptide which can be isolated from tarantulas. Stromatoxin 1 selectively inhibits K(V)2.1, K(V)2.2, K(V)4.2, and K(V)2.1/9.3 channels. K(V)2.1 and K(V)2.2, but not K(V)4.2, channel subunits play a key role in opposing both myogenic and neurogenic urinary bladder smooth muscle (UBSM) contractions in rats .
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Cat. No.: HY-P5873
Synonyms: JZTX-X
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Jingzhaotoxin-X (JZTX-X) is a selective Kv4.2 and Kv4.3 potassium channels inhibitor. Jingzhaotoxin-X causes long-lasting mechanical hyperalgesia .
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Cat. No.: HY-114540
CAS No.: 185855-91-8
Research Areas:  

Neurological Disease

CP-339818 is a non-peptide Kv1.3 channel (IC50 = 200 nM) and Kv1.4 channel blocker. CP 339818 inhibits HCN channel with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl -). CP-339818 has significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. CP-339818 selectively blocked Kv1.3, thereby inhibiting the activation process of human T cells. CP-339818 can be used to study the physiological functions of HCN and Kv channels .
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Cat. No.: HY-P87415
Synonyms: Kiaa1044, MNCb-7013, Kcnd2, A-type voltage-gated potassium channel KCND2, Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv4.2

Host:  

Mouse

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P87415A
Synonyms: Kiaa1044, MNCb-7013, Kcnd2, A-type voltage-gated potassium channel KCND2, Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv4.2

Host:  

Mouse

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P86936
Synonyms: KCD2 antibody; KCND 2 antibody; KCND2 antibody; KCND2_HUMAN antibody; KIAA1044 antibody; MGC119702 antibody; MGC119703 antibody; Potassium voltage gated channel Shal related subfamily member 2 antibody; Potassium voltage-gated channel subfamily D member 2 antibody; RK 5 antibody; KCD2 antibody; KCND 2 antibody; KCND2 antibody; KCND2_HUMAN antibody; KIAA1044 antibody; MGC119702 antibody; MGC119703 antibody; Potassium voltage gated channel Shal related subfamily member 2 antibody; Potassium voltage-gated channel subfamily D member 2 antibody; RK 5 antibody; RK5 antibody; Voltage gated potassium channel Kv4.2 antibody; Voltage gated potassium channel subunit Kv4.2 antibody; Voltage sensitive potassium channel antibody; Voltage-gated potassium channel subunit Kv4.2 antibody;

Host:  

Mouse

Application:  

IHC-F, IHC-P, WB

Reactivity:  

Mouse, Rat

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Cat. No.: HY-P5157
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

BmP02 is a selective Kv1.3 channel blocker and a highly-selective Kv4.2 modulator, which can be isolated from Chinese scorpion (Buthus martensi Karsch) venom. BmP02 also delays the inactivation of Kv4.2 in HEK293T cells, with an EC50 value of ~850 nM. BmP02 inhibits the transient outward potassium currents (Ito) in ventricular muscle cells .
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Cat. No.: HY-108588R
CAS No.: 426834-69-7
NS5806 (Standard) is the analytical standard of NS5806 (HY-108588). This product is intended for research and analytical applications. NS5806, a potent potassium current activator, increases KV4.3/KChIP2 peak current amplitudes with an EC50 of 5.3 μM. NS5806 slows KV4.3 and KV4.2 current dacay in channel complexes containing KChIP2 .
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