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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
LIFR
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "LIFR" in MCE Product Catalog:
11
11 Cited Publications
EC359 is a potent, selective, high affinity and orally active leukemia inhibitory factor receptor (LIFR) inhibitor with a Kd of 10.2 nM, which directly interacts with LIFR to effectively block LIF/LIFR interactions . EC359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-178477
Research Areas:
LIFR/GPBAR1 modulator 1 is an orally active, potent GPBAR1 agonist (EC50 = 0.2 μM) and LIFR inhibitor (IC50 = 7.9 μM). LIFR/GPBAR1 modulator 1 upregulates leukaemia inhibitory factor (LIF)-mediated mRNA expression of LIFR and GPBAR1 and significantly reduces the expression of pro-fibrosis markers (COL1A1, ASMA, and TGFβ), and reduces TIMP1 expression and increases MMP9 expression. LIFR/GPBAR1 modulator 1 can be used for the study of human fibrotic disorders .
Cat. No.: HY-RS07641
Target:
Research Areas:
LIFR Human Pre-designed siRNA Set A contains three designed siRNAs for LIFR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23643
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Lifr Rat Pre-designed siRNA Set A contains three designed siRNAs for Lifr gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-169192
CAS No.: 2409154-23-8
Target:
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BAR-2227 (compound 3a) is a FXR agonist and LIFR inhibitor. BAR-2227 can be used to study liver fibrosis and inflammation .
Cat. No.: HY-RS17192
Target:
Research Areas:
Lifr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lifr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P705457
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Leukemia inhibitory factor receptor; LIF-R; CD118
Cat. No.: HY-P700418
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIFR; leukemia inhibitory factor receptor alpha; leukemia inhibitory factor receptor; CD118; LIF receptor; CD118 antigen; SWS; SJS2; STWS; LIF-R; FLJ98106; FLJ99923;
Cat. No.: HY-P811345
Synonyms: CD118, Leukemia inhibitory factor receptor, LIF receptor, LIF-R, LIFR
Cat. No.: HY-P86943
Synonyms: CD118 antibody; CD118 antigen antibody; FLJ98106 antibody; FLJ99923 antibody; Leukemia inhibitory factor receptor alpha antibody; Leukemia inhibitory factor receptor antibody; LIF R antibody; LIF receptor antibody; LIF-R antibody; LIFR antibody; CD118 antibody; CD118 antigen antibody; FLJ98106 antibody; FLJ99923 antibody; Leukemia inhibitory factor receptor alpha antibody; Leukemia inhibitory factor receptor antibody; LIF R antibody; LIF receptor antibody; LIF-R antibody; LIFR antibody; LIFR_HUMAN antibody; SJS2 antibody; STWS antibody; SWS antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
