17 Results for "

LILRB2

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "LILRB2" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-RS07652
Research Areas:  

Others

LILRB2 Human Pre-designed siRNA Set A contains three designed siRNAs for LILRB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P990061
CAS No.: 2640981-19-5
Synonyms: JTX 8064
Polzastobart (JTX-8064) is a humanized IgG4 monoclonal antagonist antibody that selectively binds LILRB2 and prevents it from binding its ligands, classical and non-classical MHC I molecules. Polzastobart enhances pro-inflammatory cytokine production in macrophages by blocking the ability of LILRB2 to bind HLA-A/B and/or HLA-G, a marker of immunotolerance on cancer cells. Polzastobart is a macrophage immune checkpoint inhibitor .
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Cat. No.: HY-RS24023
Research Areas:  

Others

Lilrb2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lilrb2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991306

Research Areas:  

Cancer

ATG-032 is a human monoclonal antibody (mAb) targeting LILRB2/ILT4. ATG-032 can be used in haematological malignancies research.
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Cat. No.: HY-P992388

Target:  

LILRB

Research Areas:  

Cancer

IO-108 is a humanized IgG4 monoclonal antibody and a competitive inhibitor of LILRB2, with a KD value of 1.97 nM. IO-108 competitively blocks the binding of LILRB2 to its ligands including HLA-G, MHC-I, ANGPTL2 and SEMA4A, reprograms tumor-associated myeloid cells, drives the conversion of suppressive myeloid cells into a pro-inflammatory phenotype, and restores the cytotoxic activity of T cells and NK cells. IO-108 inhibits tumor growth in LILRB2 transgenic mouse models. IO-108 can be used for the research of solid tumors [2].
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Cat. No.: HY-P992353

Target:  

LILRB

Research Areas:  

Cancer

ES009 is a high-affinity LILRB2 antagonist, with IC50 values of 14.07 nM and 18.61 nM for inhibiting hLILRB2-huANGPTL3 and hLILRB2-huANGPTL4, respectively. ES009 specifically blocks the interactions between LILRB2 and MHC class I as well as non-MHC ligands, thereby effectively inhibiting receptor activation. ES009 can reprogram anti-inflammatory myeloid cells and induce their conversion to a pro-inflammatory phenotype, and also reverse the T cell suppression mediated by macrophages. When combined with anti-PD-1 blockade therapy, ES009 synergistically enhances T cell activation. ES009 can be used in research related to advanced solid tumors and ovarian cancer [2] .
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Cat. No.: HY-P78841
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LILRB2; ILT4; LIR2; MIR10; CD85d
Species:  
Source:  
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Cat. No.: HY-P78842
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LILRB2; ILT4; LIR2; MIR10; CD85d
Species:  
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Cat. No.: HY-P77739
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD85d; ILT4; ILT-4; ILT4CD85d; LILRB2; LIR2; MIR10
Species:  
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Cat. No.: HY-P78478
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD85d; ILT4; ILT-4; ILT4CD85d; LILRB2; LIR2; MIR10
Species:  
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Cat. No.: HY-P77737
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD85d; ILT4; ILT-4; ILT4CD85d; LILRB2; LIR2; MIR10
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Cat. No.: HY-P78483
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD85d; ILT4; ILT-4; ILT4CD85d; LILRB2; LIR2; MIR10
Species:  
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Cat. No.: HY-P84671
Synonyms: ILT4; LIR2; CD85D; ILT-4; LIR-2; MIR10; MIR-10

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84671A
Synonyms: ILT4; LIR2; CD85D; ILT-4; LIR-2; MIR10; MIR-10

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P70168
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuLeukocyte immunoglobulin-like receptor subfamily B member 2/LILRB2, His; Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2; LIR-2; Leukocyte Immunoglobulin-Like Receptor 2; CD85 Antigen-Like Family Member D; Immunoglobulin-Like Transcript 4; ILT-4; Monocyte/Macrophage Immunoglobulin-Like Receptor 10; MIR-10; CD85d; L
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Cat. No.: HY-P704761
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuLeukocyte immunoglobulin-like receptor subfamily B member 2/LILRB2, His; Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2; LIR-2; Leukocyte Immunoglobulin-Like Receptor 2; CD85 Antigen-Like Family Member D; Immunoglobulin-Like Transcript 4; ILT-4; Monocyte/Macrophage Immunoglobulin-Like Receptor 10; MIR-10; CD85d; L
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Cat. No.: HY-P72396
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIR-2; CD85 Antigen-Like Family Member D; Immunoglobulin-Like Transcript 4; ILT-4; CD85d; ILT4; LIR2; MIR10
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