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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
58 Results for "
MAPT
" in MedChemExpress (MCE) Product Catalog:
Products (58)
58 Results for "MAPT" in MCE Product Catalog:
1
1
1 Cited Publications
Cat. No.: HY-P70589
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DDPAC; FLJ31424; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; MAPT; MGC138549; microtubule-associated protein tau; MSTD; MSTDMAPTL; MTBT1; MTBT1Neurofibrillary tangle protein; MTBT2; Neurofibrillary tangle protein; PHF-tau; PPND; Tau; TAUPaired helical filament-tau; Tau-441
Cat. No.: HY-P4808
CAS No.: 329897-62-3
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Cat. No.: HY-132582
CAS No.: 2304711-06-4
Synonyms: IONIS-MAPTRx; BIIB080; ISIS 814907
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Diranersen (IONIS-MAPTRx) is an antisense oligonucleotide that targets the human MAPT gene to inhibit the production of tau protein. Diranersen can be used in research related to Alzheimer's disease and tauopathies .
Cat. No.: HY-132582C
Purity: 91.82%
Synonyms: IONIS-MAPTRx sodium; BIIB080 sodium; ISIS 814907 sodium
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Diranersen (IONIS-MAPTRx) sodium is an antisense oligonucleotide that targets the human MAPT gene to inhibit the production of tau protein. Diranersen sodium can be used in research related to Alzheimer's disease and tauopathies .
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BPN-15477 is an orally active, blood-brain barrier-permeable splicing modulator compound (SMC). BPN-15477 restores the correct splicing of exon 20 of the elongator complex protein 1 (ELP1) (EC50 = 1.9 μM), thereby significantly increasing the in vivo functional protein levels in all tissues including the brain. BPN-15477 can be used in the research of familial dysautonomia, such as frontotemporal dementia .
Cat. No.: HY-P991373
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Cat. No.: HY-RS08141
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Mapt Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mapt gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-174215
CAS No.: 3063511-09-8
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TAU-IN-3 (Compound 2) is an orally active TAU inhibitor. TAU-IN-3 inhibits the expression of MAPT exon 10 DDPAC mutant gene in HeLa cells (IC50: 0.6 µM). TAU-IN-3 reduces the 4R/3R MAPT mRNA ratio in HeLa cells transfected with WT or DDPAC minigenes. TAU-IN-3 inhibits the insertion of endogenous MAPT exon 10 and the production of 4R tau protein in cells. TAU-IN-3 modulates tau splicing in htau mice and improves the associated behavioral phenotypes. TAU-IN-3 can be used to study neurodegenerative diseases .
Cat. No.: HY-RS08140
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MAPT Human Pre-designed siRNA Set A contains three designed siRNAs for MAPT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08142
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Mapt Rat Pre-designed siRNA Set A contains three designed siRNAs for Mapt gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P71752
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAPT; Mtapt; Tau; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
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Cat. No.: HY-P83700A
Synonyms: MAPT; MAPTL; MTBT1; TAU; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
Cat. No.: HY-P73618A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAPT; Mtapt; Tau; Microtubule-associated protein tau; PHF-tau
Cat. No.: HY-P71753
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAPT; Mtapt; Tau; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
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Source:
Cat. No.: HY-P704324
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DDPAC; FTDP-17; MAPT; MSTD; MTBT1; Tau; PHF-tau; TAU
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
