15 Results for "

MICB

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "MICB" in MCE Product Catalog:

Cat. No.: HY-P99389
CAS No.: 2242758-08-1
Synonyms: JNJ-64304500; IPH-2301; NN-8555
Tesnatilimab (JNJ-64304500) is a human IgG4 monoclonal antibody targeting NKG2D, with a KD value of 9.2 pM . Tesnatilimab blocks the binding of ligands to the NKG2D receptor, thereby inhibiting downstream proinflammatory cytokine, cytotoxic mediator signaling pathways and proinflammatory immune responses. Tesnatilimab is applicable to research related to Crohn's disease .
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Cat. No.: HY-P990467

Research Areas:  

Inflammation/Immunology

The Anti-MICB Antibody is a humanized antibody expressed in CHO cells, targeting MICB. The Anti-MICB Antibody contains a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 143.66 kDa. The isotype control for the Anti-MICB Antibody can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-RS08430
Research Areas:  

Others

MICB Human Pre-designed siRNA Set A contains three designed siRNAs for MICB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-101780A
CAS No.: 1793059-58-1
Synonyms: EDO-S101 hydrochloride; NL-101 hydrochloride
Target:  

HDAC

Research Areas:  

Cancer

Tinostamustine hydrochloride (EDO-S101 hydrochloride) is a compound with anti-multiple myeloma activity and the ability to promote CD38 expression. Tinostamustine hydrochloride enhances the sensitivity of tumor cells to the anti-CD38 monoclonal antibody daratumumab by increasing the acetylation level of histone H3. Tinostamustine hydrochloride can increase the expression of MICA and MICB, thereby activating NK cells. Tinostamustine hydrochloride can significantly delay tumor growth and improve the survival rate of mice .
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Cat. No.: HY-P701023
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MICB; MIC-B; PERB11.2
Species:  
Source:  
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Cat. No.: HY-P78491
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MICB; MIC-B; PERB11.2
Species:  
Source:  
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Cat. No.: HY-P78174
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MICB; MIC-B; PERB11.2
Species:  
Source:  
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Cat. No.: HY-RS23997
Research Areas:  

Others

Micb Rat Pre-designed siRNA Set A contains three designed siRNAs for Micb gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P73294
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MHC class I polypeptide-related sequence B; MIC-B; PERB11.2
Species:  
Source:  
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Cat. No.: HY-P73293
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MHC class I polypeptide-related sequence B; MIC-B; PERB11.2
Species:  
Source:  
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Cat. No.: HY-P704789
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MHC class I polypeptide-related sequence B; MIC-B; PERB11.2
Species:  
Source:  
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Cat. No.: HY-P81721
Synonyms: MIC-B; PERB11.2

Host:  

Rabbit

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P811307
Synonyms: PERB11.2, MICB, MHC class I polypeptide-related sequence B, MIC-B

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P992391
Synonyms: IPH43

Research Areas:  

Cancer

IPH4301 is a monoclonal antibody targeting MICA/B, with dual activities of cytotoxicity and immunoregulation . IPH4301 blocks the interaction between MICA/B and NKG2D, inhibits their hydrolysis into soluble sMICA/B, and mediates antibody-dependent cellular cytotoxicity and antibody-dependent cellular phagocytosis against tumor cells expressing MICA/MICB. IPH4301 restores the expression and function of NKG2D on primary NK cells and T cells, reverses the immunosuppression induced by M2 macrophages, and enhances NK cell-mediated tumor cell apoptosis. IPH4301 can be used in research related to cancer and triple-negative breast cancer .
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Cat. No.: HY-P83760
Synonyms: HLA class I antigen antibody; FLJ36918 antibody; FLJ60820 antibody; MGC111087 antibody; MGC21250 antibody; MHC class I chain related gene A protein antibody; MIC A antibody; micA antibody; MICA_HUMAN antibody; OTTHUMP00000029088 antibody; PERB11.1 antibody; Stress inducible class I homolog antibody; MHC class I chain related protein B antibody; MICB antibody MICB_HUMAN antibody PERB11.2 antibody Stress inducible class I homolog antibody

Host:  

Rabbit

Application:  

WB, IP, FC

Reactivity:  

Human

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