27 Results for "

MUSK

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "MUSK" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N0633
CAS No.: 541-91-3
Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate .
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3
3 Cited Publications
Cat. No.: HY-15590
CAS No.: 915720-21-7
Purity:  98.92%
Synonyms: AZD1332
Target:  

Trk Receptor

Research Areas:  

Cancer

AZ-23 is an ATP-competitive and orally bioavailable Trk kinase A/B/C inhibitor with IC50s of 2 nM (TrkA), 8 nM (TrkB), 24 nM (FGFR1), 52 nM (Flt3), 55 nM (Ret), 84 nM (MuSk), 99 nM (Lck), respectively.
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1
1 Cited Publications
Cat. No.: HY-N3127
CAS No.: 480-23-9
Orobol is one of the major soy isoflavones and has various pharmacological activities, including anti-skin-aging and anti-obesity effects. Orobol inhibits CK1ε, VEGFR2, MAP4K5, MNK1, MUSK, TOPK, and TNIK (IC50=1.24-4.45 μM). Orobol also inhibits PI3K isoforms (IC50=3.46-5.27 μM for PI3K α/β/γ/K/δ) .
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1
1 Cited Publications
Cat. No.: HY-N2045
CAS No.: 81-14-1
Musk ketone is a widely used artificial fragrance. Musk ketone is also a cytochrome P450 enzyme inducer. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. In the brain, musk ketone is neuroprotective against stroke injury through inhibition of cell apoptosis .
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Cat. No.: HY-W100026
CAS No.: 1222-05-5
Galaxolide is a polycyclic musk synthetic fragrance. Galaxolide possesses endocrine-disrupting activity and can exert anti-androgenic/estrogenic effects. Galaxolide exhibits in vivo androgenic activity in immature rats . Galaxolide can be used in studies related to endocrine disruption .
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Cat. No.: HY-P991066
CAS No.: 2966023-63-0
Synonyms: ARGX-119

Target:  

nAChR

Research Areas:  

Neurological Disease

ARGX-119 is a first-in-class humanized agonist monoclonal antibody specific for muscle-specific kinase (MuSK). ARGX-119 can be used for the study of neuromuscular diseases. The isotype control for ARGX-119 can refer to Human IgG1 lambda1, Isotype Control (HY-P99992) .
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Cat. No.: HY-P5438
Research Areas:  

Others

Srctide is a biological active peptide. (This is a peptide substrate for many protein kinases, such as Blk, BTK, cKit, EPHA1, EPHB2, EPHB3, ERBB4, FAK, Flt3, IGF-1R, ITK, Lck, MET, MUSK, Ret, Src, TIE2, TrkB, VEGF-R1 (Flt-1) and VEGF-R2 (KDR).)
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Cat. No.: HY-116108
CAS No.: 145-39-1
Synonyms: MUSK tibetine
Musk tibetene (Musk tibetine) is a nitro musk compound with carcinogenic activity. Musk tibetine reveals no genotoxicity in the micronucleus test with human lymphocytes and human hepatoma cell line .
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Cat. No.: HY-A0287
CAS No.: 911-45-5
Synonyms: Clomifene; (Z/E)-Enclomiphene; (Z/E)-Enclomifene
Target:  

Estrogen Receptor/ERR

Research Areas:  

Metabolic Disease Cancer

Clomiphene (Clomifene; (Z/E)-Enclomiphene; (Z/E)-Enclomifene) is an orally active ovulation-inducing agent. Clomiphene binds to hypothalamic estrogen receptors to elevate FSH levels, and exhibits antiestrogenic or estrogenic properties. Clomiphene can induce erturbations during meiotic maturation and cytogenetic abnormalities in mouse oocytes. Clomiphene ameliorates memory impairment in PCOS models. Clomiphene mobilizes cytosolic calcium and reduces viability in prostate cancer cells. Clomiphene can be used for the research of polycystic ovary syndrome (PCOS) and prostate cancer .
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Cat. No.: HY-P990473

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Anti-MUSK Antibody is a humanized antibody expressed in CHO that targets MUSK. The Anti-MUSK Antibody contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 143.86 kDa. For the isotype control of Anti-MUSK Antibody, please refer to Human IgG1 (L234A/L235A) kappa, Isotype Control (HY-P991207).
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Cat. No.: HY-W744618
CAS No.: 7779-50-2
Ambrettolide is a natural macrolide compound that possesses a warm and delicate musk aroma, with a hint of animal fragrance .
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Cat. No.: HY-W721109
CAS No.: 10403-00-6
Target:  

Olfactory Receptor

Research Areas:  

Neurological Disease

(R)-(-)-Muscone, a musk-smelling compound, is an odorant receptor OR5AN1 agonist .
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Cat. No.: HY-RS08852
Research Areas:  

Others

MUSK Human Pre-designed siRNA Set A contains three designed siRNAs for MUSK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23912
Research Areas:  

Others

Musk Rat Pre-designed siRNA Set A contains three designed siRNAs for Musk gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N2045R
CAS No.: 81-14-1
Bulleyaconitine A (Standard) is the analytical standard of Bulleyaconitine A. This product is intended for research and analytical applications. 0
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Cat. No.: HY-N0633R
CAS No.: 541-91-3
Muscone (Standard) is the analytical standard of Muscone. This product is intended for research and analytical applications. Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate .
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Cat. No.: HY-P5527F
Target:  

Peptides

Research Areas:  

Others

FAM-CSKtide is a biological active peptide. (This is a FAM labeled peptide substrate (Abs/Em = 494/521 nm) for C-terminal Src kinase (Csk) and many other kinases such as Axl, cKit, ERBB4, Fes, Flt3, IGF-1 R, MET, MUSK, PYK2, Ret, TIE2, TrkA, VEGF-R1 and VEGF-R2.)
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Cat. No.: HY-RS17455
Research Areas:  

Others

Musk Mouse Pre-designed siRNA Set A contains three designed siRNAs for Musk gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P71568
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MUSK; Nsk2; Muscle; skeletal receptor tyrosine-protein kinase; EC 2.7.10.1; Muscle-specific tyrosine-protein kinase receptor; MUSK; Muscle-specific kinase receptor
Species:  
Source:  
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Cat. No.: HY-P703959
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: EC:2.7.10.1; MUSK; Muscle-specific kinase receptor
Species:  
Source:  
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