480-23-9
480-23-9
Chemical Structure
Orobol
- CAS No.: 480-23-9
- Formula:C15H10O6
- Molecular Weight:286.24
IUPAC Name: 3-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
InChIKey: IOYHCQBYQJQBSK-UHFFFAOYSA-N
SMILES: O=C1C2=C(O)C=C(O)C=C2OC=C1C3=CC(O)=C(O)C=C3
Biological Activity: Orobol is one of the major soy isoflavones and has various pharmacological activities, including anti-skin-aging and anti-obesity effects. Orobol inhibits CK1ε, VEGFR2, MAP4K5, MNK1, MUSK, TOPK, and TNIK (IC50=1.24-4.45 μM). Orobol also inhibits PI3K isoforms (IC50=3.46-5.27 μM for PI3K α/β/γ/K/δ)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Orobol | 98.66% | Orobol is one of the major soy isoflavones and has various pharmacological activities, including anti-skin-aging and anti-obesity effects. Orobol inhibits CK1ε, VEGFR2, MAP4K5, MNK1, MUSK, TOPK, and TNIK (IC50=1.24-4.45 μM). Orobol also inhibits PI3K isoforms (IC50=3.46-5.27 μM for PI3K α/β/γ/K/δ). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.88
HY-N7981Pratensein -
Similarity Score 0.87
HY-N18593'-O-Methylorobol -
Similarity Score 0.86
HY-N17352′-Hydroxygenistein -
Similarity Score 0.85
HY-14596Genistein -
Similarity Score 0.83
HY-124953R7,3',4'-Trihydroxyisoflavone (Standard) -
Similarity Score 0.81
HY-W7520536-Hydroxygenistein -
Similarity Score 0.80
HY-14595RBiochanin A (Standard) -
Similarity Score 0.79
HY-N78067,3'-Di-O-Methylorobol -
Similarity Score 0.79
HY-N10977Piscerygenin -
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