5 Results for "

Magnoflorine

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Magnoflorine" in MCE Product Catalog:

1
(+)-Magnoflorine chloride
(+)-Magnoflorine chloride
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1 Cited Publications
Cat. No.: HY-N0535
CAS No.: 6681-18-1
Synonyms: Magnoflorine chloride; α-Magnoflorine chloride; Thalictrine chloride
Category:  

Metabolic Disease Plants Aristolochiaceae Infection Alkaloids Piperidine Alkaloids other families Aristolochia debilis Sieb. et Zucc. Phenols Polyphenols Disease Research Fields

Target:  

Fungal Autophagy Apoptosis PINK1/Parkin NOD-like Receptor (NLR) Caspase JNK NF-κB Sirtuin AMPK Reactive Oxygen Species (ROS)

(+)-Magnoflorine (α-Magnoflorine) chloride is an orally active aporphine alkaloid with multiple biological activities. (+)-Magnoflorine chloride promotes Parkin/PINK1-mediated mitochondrial autophagy, inhibits the activation of NLRP3/Caspase-1 pathway, regulates the intestinal microbiota, and exhibits significant anti-inflammatory and immunomodulatory activities. (+)-Magnoflorine chloride inhibits JNK and TLR4/NF-κB signaling pathways, activates Sirt1/AMPK pathway, alleviates neuronal oxidative stress and apoptosis. Magnoflorine chloride upregulates miR-410-3p, inhibits HMGB1/NF-κB pathway, and has anti-tumor activity. (+)-Magnoflorine chloride also has significant antifungal activity .
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1
(+)-Magnoflorine iodide
(+)-Magnoflorine iodide
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1 Cited Publications
Cat. No.: HY-N0334A
CAS No.: 4277-43-4
Synonyms: Magnoflorine iodide; α-Magnoflorine iodide; Thalictrine iodide
Category:  

Alkaloids Magnoliaceae Metabolic Disease Phenols Polyphenols Magnolia Liliflora Desr. Plants Disease Research Fields Isoquinoline Alkaloids

Target:  

Fungal Autophagy Apoptosis PINK1/Parkin NOD-like Receptor (NLR) Caspase JNK NF-κB Sirtuin AMPK Reactive Oxygen Species (ROS)

(+)-Magnoflorine (α-Magnoflorine) iodide is an orally active aporphine alkaloid with multiple biological activities. (+)-Magnoflorine iodide promotes Parkin/PINK1 -mediated mitochondrial autophagy, inhibits the activation of NLRP3/Caspase-1 pathway, regulates the intestinal microbiota, and exhibits significant anti-inflammatory and immunomodulatory activities. (+)-Magnoflorine iodide inhibits JNK and TLR4/NF-κB signaling pathways, activates Sirt1/AMPK pathway, alleviates neuronal oxidative stress and apoptosis. Magnoflorine upregulates miR-410-3p, inhibits HMGB1/NF-κB pathway, and has anti-tumor activity. (+)-Magnoflorine iodide also has significant antifungal activity .
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(+)-Magnoflorine
(+)-Magnoflorine
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Cat. No.: HY-N0334
CAS No.: 2141-09-5
Synonyms: Magnoflorine; α-Magnoflorine; Thalictrine
Category:  

Alkaloids Ranunculaceae Coptis chinensis Franch. Metabolic Disease Phenols Polyphenols Plants Disease Research Fields Isoquinoline Alkaloids

Target:  

Fungal Autophagy Apoptosis PINK1/Parkin NOD-like Receptor (NLR) Caspase JNK NF-κB Sirtuin AMPK Reactive Oxygen Species (ROS)

(+)-Magnoflorine (α-Magnoflorine) is an orally active aporphine alkaloid with multiple biological activities. (+)-Magnoflorine promotes Parkin/PINK1 -mediated mitochondrial autophagy, inhibits the activation of NLRP3/Caspase-1 pathway, regulates the intestinal microbiota, and exhibits significant anti-inflammatory and immunomodulatory activities. (+)-Magnoflorine inhibits JNK and TLR4/NF-κB signaling pathways, activates Sirt1/AMPK pathway, alleviates neuronal oxidative stress and apoptosis. Magnoflorine upregulates miR-410-3p, inhibits HMGB1/NF-κB pathway, and has anti-tumor activity. (+)-Magnoflorine also has significant antifungal activity .
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(+)-Magnoflorine chloride (Standard)
(+)-Magnoflorine chloride (Standard)
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Cat. No.: HY-N0535R
CAS No.: 6681-18-1
Synonyms: Magnoflorine chloride (Standard); α-Magnoflorine chloride (Standard); Thalictrine chloride (Standard)
Category:  

Alkaloids Piperidine Alkaloids other families Aristolochia debilis Sieb. et Zucc. Phenols Polyphenols Plants Aristolochiaceae

Target:  

Reference Standards Fungal

(+)-Magnoflorine (chloride) (Standard) is the analytical standard of (+)-Magnoflorine (chloride). This product is intended for research and analytical applications. Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm . Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity .
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Antidepressant agent 5
Antidepressant agent 5
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Cat. No.: HY-156079
CAS No.: 1071049-42-7
Target:  

Monoamine Oxidase

Research Areas:  

Neurological Disease

Antidepressant agent 5 (Compound 3i) is a 7-substituted tetrahydroisoquinolines derivatives. Antidepressant agent 5 exhibits almost equal antidepressant activity compared with magnoflorine. ntidepressant agent 5 can be used for depressive disorder research .
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