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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
NH3
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "NH3" in MCE Product Catalog:
5
5 Cited Publications
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NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment [3]. NH-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Synonyms: LY-488756
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Lubabegron is a potent modulator of β-adrenergic receptor (β-AR). Lubabegron demonstrates antagonistic behavior at the β1 and β 2 receptor subtypes and agonistic behavior at the β 3 receptor subtype in cattle. Lubabegron reduces NH3 gas emissions from an animal or its waste. Lubabegron is available as an animal supplement .
Synonyms: NBPT
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N-Butylthiophosphoric triamide (NBPT) is a potent urease inhibitor. Butylthiophosphoric triamide inhibits nitrification and reduces the conversion of urea to NH3 gas .
Cat. No.: HY-174262
CAS No.: 3082703-49-6
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IL4I1-IN-1 (Compound Ex 232 pg 200) is a selective interleukin 4-induced protein 1 (IL4I1) inhibitor with an EC50 of 2 nM. IL4I1-IN-1 inhibits IL4I1-mediated oxidative deamination of phenylalanine, reducing the production of phenylpyruvate, H2O2 and NH3. IL4I1-IN-1 is promising for research of cancers with high IL4I1 expression, such as endometrial carcinoma, ovarian cancer, and triple-negative breast cancer .
Cat. No.: HY-W781133
CAS No.: 106343-54-8
Synonyms: cis-[Pt(NH3)2N1-pyridineCl]Cl
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cDPCP (cis-[Pt(NH3)2(N1-pyridine)Cl]Cl) is a DNA crosslinking agent and also a substrate for OCT1 and OCT2. DPCP exhibits anticancer activity and can improve the survival rate of sarcoma-180 mice. cDPCP is suitable for the research of colorectal cancer and cancers with appropriate cation transporters .
Synonyms: Biotin Labeled Doxorubicin
Dox-btn2 is a biotin labeled Doxorubicin (HY-15142A), with a biotin label at the point of conjugation to doxorubicin at 3'-NH2. Dox-btn2 can be used for cell imaging. While Doxorubicin is mainly accumulated in the nucleus, while Dox-btn2 is mainly located in the cytoplasm .
Cat. No.: HY-169206
CAS No.: 3126204-69-8
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PF-3166 is a PAD2 inhibitor (IC50=150 nM) that is competitive with Ca 2+. TPF-3166 insignificantly inhibits PAD3 or PAD4 (80 μM). PF-3166 also inhibits NH3 release (IC50=580 nM). .
Cat. No.: HY-123012A
CAS No.: 391926-19-5
Synonyms: LY-591281; LY-488756 fumarate
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Lubabegron fumarate is a potent modulator of β-adrenergic receptor (β-AR). Lubabegron fumarate demonstrates antagonistic behavior at the β1 and β 2 receptor subtypes and agonistic behavior at the β 3 receptor subtype in cattle. Lubabegron fumarate reduces NH3 gas emissions from an animal or its waste. Lubabegron fumarate is available as an animal supplement .
Cat. No.: HY-P1218B
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Cat. No.: HY-107199R
CAS No.: 94317-64-3
Synonyms: NBPT (Standard)
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N-Butylthiophosphoric triamide (Standard) (NBPT (Standard)) is the analytical standard of N-Butylthiophosphoric triamide (HY-107199). This product is intended for research and analytical applications. N-Butylthiophosphoric triamide (NBPT) is a potent urease inhibitor. Butylthiophosphoric triamide inhibits nitrification and reduces the conversion of urea to NH3 gas .
Cat. No.: HY-178810S
Synonyms: DOPS-NH3-d62
Cat. No.: HY-E71011
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N-Carbamoylsarcosine Amidase, E. coli, belongs to the hydrolase family. This family of enzymes acts on carbon-nitrogen bonds other than peptide bonds, particularly the carbon-nitrogen bonds in linear amides, and participates in the metabolism of arginine and proline. The two substrates of N-Carbamoylsarcosine Amidase, E. coli, are N-carbamoylsarcosine and H2O, while its three products are sarcosine, CO2, and NH3.ions to the healing immune response.
Cat. No.: HY-E70926
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Lysine Oxidase, Trichoderma viride (EC 1.4.3.14), is an oxidoreductase that acts on the CH-NHsub>2 group in the donor molecule and uses oxygen as the acceptor. Lysine Oxidase participates in the degradation of lysine. The three substrates of lysine oxidase are L-lysine, O2, and H2O, while its three products are 6-amino-2-oxohexanoic acid, NH3, and H2O2.
PI3K-IN-32 is an imidazopyridine derivative with a 3-NH2 substituent, and also a PI3K p110α inhibitor. PI3K-IN-32 is applicable for cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
