![[Lys5,MeLeu9,Nle10]Neurokinin A(4-10)](https://file.medchemexpress.com/product_pic/hy-p3849.gif "Click to View [Lys5,MeLeu9,Nle10]Neurokinin A(4-10) Product Detail")
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![[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA](https://file.medchemexpress.com/product_pic/hy-p1279a.gif "Click to View [Lys5,MeLeu9,Nle10]-NKA(4-10) TFA Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
NKA
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "NKA" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-W013375
CAS No.: 76721-89-6
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Thiorphan is a selective neprilysin (NEP) inhibitor with an IC50 of 6.9 nM. Thiorphan competitively binds to NEP and blocks its activity, preventing the degradation of neuropeptides such as substance P (SP) and neurokinin NKA. In the field of neonatal brain injury research, Thiorphan can increase the levels of SP and NKA, activate NK1 and NK2 receptors and downstream transduction pathways, and inhibit excessive activation of NMDA receptors. Thus, Thiorphan can protect neocortical neurons from excitotoxic cell death. Thiorphan may also inhibit NEP from enhancing bronchoconstriction and can be used in the study of respiratory diseases .
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3 Cited Publications
Cat. No.: HY-P0197
CAS No.: 86933-74-6
Synonyms: Substance K; Neurokinin α; Neuromedin L; NKA
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3 Cited Publications
Cat. No.: HY-P0197A
CAS No.: 2828433-19-6
Synonyms: Substance K TFA; Neurokinin α TFA; Neuromedin L TFA; NKA TFA
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Cat. No.: HY-P3849
CAS No.: 149270-28-0
Synonyms: LMN-NKA
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Cat. No.: HY-151413A
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Cat. No.: HY-128537
CAS No.: 398507-81-8
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DNK-333 is a potent and balanced dual NK1 and NK2 receptor antagonist with IC50 values of 4.8 nM and 5.5 nM, respectively. DNK-333 blocks the Neurokinin A (NKA) (HY-P0197)-induced bronchoconstriction in asthma .
Cat. No.: HY-P1279
CAS No.: 137565-28-7
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Cat. No.: HY-P1279A
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Cat. No.: HY-117053
CAS No.: 169340-04-9
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ZM 253270 is a species-selective non-peptide NK-2 receptor (NK-2R) antagonist. ZM 253270 competitively inhibits the binding of [ 3H]NKA to native or cloned NK-2R from hamster bladder (Ki=2 nM), but has a weaker inhibitory effect (48-fold) on the binding of [ 3H]NKA to cloned human NK-2R .
Cat. No.: HY-P12114
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Cat. No.: HY-P81130
Synonyms: Hs.2563; Neurokinin 1; Neurokinin 2; Neurokinin A; Neurokinin alpha; Neuromedin L; Neuropeptide gamma; NKA; NKNA; PPT; Protachykinin 1 precursor; Substance K; Substance P; TAC1; TAC2; Tachykinin 1; Tachykinin 2; Tachykinin precursor 1; Tachykinin1; TACI; TKN1_HUMAN.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
