Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
NKCC2
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "NKCC2" in MCE Product Catalog:
19
Target:
Research Areas:
Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na +-K +-Cl + cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC50s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively [2].
10
Target:
Research Areas:
Furosemide is a potent and orally active inhibitor of Na +/K +/2Cl - (NKCC) cotransporter, NKCC1 and NKCC2 . Furosemide is also a GABAA receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema [2].
10
10 Cited Publications
Cat. No.: HY-B0135A
CAS No.: 41733-55-5
Target:
Research Areas:
Furosemide sodium is a potent and orally active inhibitor of Na +/K +/2Cl - (NKCC) cotransporter, NKCC1 and NKCC2 . Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema [2].
Cat. No.: HY-B0135S
CAS No.: 1189482-35-6
Cat. No.: HY-17468R
CAS No.: 28395-03-1
Synonyms: Ro 10-6338 (Standard); PF 1593 (Standard)
Target:
Research Areas:
Bumetanide (Standard) is the analytical standard of Bumetanide. This product is intended for research and analytical applications. Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na +-K +-Cl + cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC50s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively [2].
Target:
Research Areas:
Furosemide (Standard) is the analytical standard of Furosemide. This product is intended for research and analytical applications. Furosemide is a potent and orally active inhibitor of Na +/K +/2Cl - (NKCC) cotransporter, NKCC1 and NKCC2 . Furosemide is also a GABAA receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema [2].
Cat. No.: HY-17468S
CAS No.: 1216739-35-3
Cat. No.: HY-17468A
CAS No.: 28434-74-4
Synonyms: Ro 10-6338 sodium; PF 1593 sodium
Target:
Research Areas:
Bumetanide sodium, a highly potent loop diuretic, is a Na +-K +-Cl + cotransporter (NKCC) blocker. Bumetanide sodium is a selective NKCC1 inhibitor, and also inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively [2].
Cat. No.: HY-B0135AR
CAS No.: 41733-55-5
Target:
Research Areas:
Furosemide (sodium) (Standard) is the analytical standard of Furosemide (sodium). This product is intended for research and analytical applications. Furosemide sodium is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2 . Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema [2].
Cat. No.: HY-P81658A
Synonyms: BSC1; NKCC2
Cat. No.: HY-RS12996
Target:
Research Areas:
SLC12A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC12A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P83742
Synonyms: BSC1 antibody;
Bumetanide sensitive sodium 3 antibody;
Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 antibody;
Kidney specific Na K Cl symporter antibody;
Kidney-specific Na-K-Cl symporter antibody;
MGC48843 antibody;
Na K 2Cl cotransporter antibody;
NKCC2 antibody;
potassiumchloride cotransporter 2 antibody;
S12A1_HUMAN antibody;
Slc12a1 antibody;
sodium potassium chloride cotransporter 2 antibody;
solute carrier family 12 (sodium/potassium/chloride transporters) antibody;
Solute carrier family 12 member 1 antibody
Cat. No.: HY-RS28547
Target:
Research Areas:
Slc12a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc12a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22029
Target:
Research Areas:
Slc12a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc12a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
