Search Result

Results for "

NKCC2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	NKCC (9) GABA Receptor (5) Reference Standards (3) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (5) Cardiovascular Disease (7) Metabolic Disease (8)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: NKCC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17468

Bumetanide Maximum Cited Publications 18 Publications Verification Ro 10-6338; PF 1593	NKCC	Cardiovascular Disease Metabolic Disease
Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na ⁺-K ⁺-Cl ⁺ cotransporter (NKCC) blocker. Bumetanide is a selective *NKCC1* inhibitor, but also inhibits NKCC2, with IC₅₀s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively ^[2].

HY-B0135

Furosemide 5+ Cited Publications	NKCC GABA Receptor	Cardiovascular Disease Metabolic Disease Cancer
Furosemide is a potent and orally active inhibitor of *Na ⁺/K ⁺/2Cl* ^- (NKCC) cotransporter*, NKCC1 and NKCC2* . Furosemide is also a GABA_A receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema ^[2].

HY-B0135A

Furosemide sodium 5+ Cited Publications	NKCC GABA Receptor	Cardiovascular Disease Metabolic Disease Cancer
Furosemide sodium is a potent and orally active inhibitor of *Na ⁺/K ⁺/2Cl* ^- (NKCC) cotransporter*, NKCC1 and NKCC2* . Furosemide sodium is also a GABA_A receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema ^[2].

HY-B0135S

Furosemide-d5	NKCC GABA Receptor	Metabolic Disease Cancer
Furosemide-d₅ is the deuterium labeled Furosemide. Furosemide is a potent and orally active inhibitor of Na+/K+/2Cl-?(NKCC) cotransporter, NKCC1 and NKCC2 .?Furosemide is also a GABAA?receptors antagonist and displays 100-fold selectivity for?α6-containing receptors than?α1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema ^[2].

HY-17468R

Bumetanide (Standard) Ro 10-6338 (Standard); PF 1593 (Standard)	Reference Standards NKCC	Cardiovascular Disease Metabolic Disease
Bumetanide (Standard) is the analytical standard of Bumetanide. This product is intended for research and analytical applications. Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na ⁺-K ⁺-Cl ⁺ cotransporter (NKCC) blocker. Bumetanide is a selective *NKCC1* inhibitor, but also inhibits NKCC2, with IC₅₀s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively ^[2].

HY-B0135R

Furosemide (Standard) 5+ Cited Publications	Reference Standards NKCC GABA Receptor	Metabolic Disease Cancer
Furosemide (Standard) is the analytical standard of Furosemide. This product is intended for research and analytical applications. Furosemide is a potent and orally active inhibitor of *Na ⁺/K ⁺/2Cl* ^- (NKCC) cotransporter*, NKCC1 and NKCC2* . Furosemide is also a GABA_A receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema ^[2].

HY-17468S

Bumetanide-d5	NKCC	Cardiovascular Disease
Bumetanide-d₅ is a deuterium labeled Bumetanide. Bumetanide is a selective Na+-K+-Cl- (NKCC1) inhibitor, weakly inhibits NKCC2, with ?IC₅₀s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively .

HY-17468A

Bumetanide sodium Ro 10-6338 sodium; PF 1593 sodium	NKCC	Cardiovascular Disease Metabolic Disease
Bumetanide sodium, a highly potent loop diuretic, is a Na ⁺-K ⁺-Cl ⁺ cotransporter (NKCC) blocker. Bumetanide sodium is a selective *NKCC1* inhibitor, and also inhibits NKCC2, with IC₅₀s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively ^[2].

HY-B0135AR

Furosemide sodium (Standard)	NKCC GABA Receptor Reference Standards	Cardiovascular Disease Metabolic Disease Cancer
Furosemide (sodium) (Standard) is the analytical standard of Furosemide (sodium). This product is intended for research and analytical applications. Furosemide sodium is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2 . Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema ^[2].

HY-RS12996

SLC12A1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SLC12A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC12A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SLC12A1 Human Pre-designed siRNA Set A SLC12A1 Human Pre-designed siRNA Set A

HY-RS28547

Slc12a1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Slc12a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc12a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Slc12a1 Rat Pre-designed siRNA Set A Slc12a1 Rat Pre-designed siRNA Set A

HY-RS22029

Slc12a1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Slc12a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc12a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Slc12a1 Mouse Pre-designed siRNA Set A Slc12a1 Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Chemical Structure

HY-B0135S

Furosemide-d5
Furosemide-d₅ is the deuterium labeled Furosemide. Furosemide is a potent and orally active inhibitor of Na+/K+/2Cl-?(NKCC) cotransporter, NKCC1 and NKCC2 .?Furosemide is also a GABAA?receptors antagonist and displays 100-fold selectivity for?α6-containing receptors than?α1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema ^[2].

Furosemide-d5

Furosemide-d₅ is the deuterium labeled Furosemide. Furosemide is a potent and orally active inhibitor of Na+/K+/2Cl-?(NKCC) cotransporter, NKCC1 and NKCC2 .?Furosemide is also a GABAA?receptors antagonist and displays 100-fold selectivity for?α6-containing receptors than?α1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema ^[2].

HY-17468S

Bumetanide-d5
Bumetanide-d₅ is a deuterium labeled Bumetanide. Bumetanide is a selective Na+-K+-Cl- (NKCC1) inhibitor, weakly inhibits NKCC2, with ?IC₅₀s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively .

Host:	Rabbit (3)
Reactivity:	Human (3) Rat (1) Mouse (1)
Application:	IHC-P (1) ICC/IF (1) WB (3)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81658

	SLC12A1 Antibody (YA1403) BSC1; NKCC2	WB	Human
	SLC12A1 Antibody (YA1403) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SLC12A1.

HY-P81658A

	SLC12A1 Antibody (YA1403)(PBS only) BSC1; NKCC2	WB	Human
	SLC12A1 Antibody (YA1403) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SLC12A1.

HY-P83742

	SLC12A1 Antibody (YA3471) BSC1 antibody; Bumetanide sensitive sodium 3 antibody; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 antibody; Kidney specific Na K Cl symporter antibody; Kidney-specific Na-K-Cl symporter antibody; MGC48843 antibody; Na K 2Cl cotransporter antibody; NKCC2 antibody; potassiumchloride cotransporter 2 antibody; S12A1_HUMAN antibody; Slc12a1 antibody; sodium potassium chloride cotransporter 2 antibody; solute carrier family 12 (sodium/potassium/chloride transporters) antibody; Solute carrier family 12 member 1 antibody	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	SLC12A1 Antibody (YA3471) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SLC12A1.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

SLC12A1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SLC12A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC12A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Slc12a1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Slc12a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc12a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Slc12a1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Slc12a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc12a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

We use cookies

MedChemExpress values your privacy and your trust is important to us. We use cookies to enhance your website experience. Some cookies are necessary to run the website. Privacy and Cookie Policy

Name
Email *

	Sorry, but the email address you supplied was invalid.