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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
Nec1
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "Nec1" in MCE Product Catalog:
561
Research Areas:
Necrostatin-1 (Nec-1) is a potent and cross the blood-brain barrier necroptosis inhibitor with an EC50 of 490 nM in Jurkat cells. Necrostatin-1 inhibits RIP1 kinase (EC50=182 nM). Necrostatin-1 is also an IDO inhibitor [1].
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34 Cited Publications
Synonyms: Necrostatin 1S; Nec-1S; 7-Cl-O-Nec1
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Necrostatin 2 racemate (Nec-1S), the Necrostatin-1 (HY-15760) stable, is a potent and specific RIPK1 inhibitor lacking the IDO-targeting effect [1].
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ISX-9 (Isoxazole 9) is a potent inducer of adult neural stem cell differentiation. ISX-9 activates Ca 2+ influx through both voltage-gated Ca 2+ channels and NMDA receptors and increases neuroD expression. ISX-9 also induces cardiomyogenic differentiation of Notch-activated epicardium-derived cells (NECs) .
Synonyms: Nec-1 (inactive control)
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Necrostatin-1 (Nec-1) (inactive control) is an inactive analog of Necrostatin-1 (HY-15760). Necrostatin-1 is a potent necroptosis inhibitor [1].
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Necrostatin-1 (Standard) is the analytical standard of Necrostatin-1. This product is intended for research and analytical applications. Necrostatin-1 (Nec-1) is a potent and cross the blood-brain barrier necroptosis inhibitor with an EC50 of 490 nM in Jurkat cells. Necrostatin-1 inhibits RIP1 kinase (EC50=182 nM). Necrostatin-1 is also an IDO inhibitor [1].
Cat. No.: HY-RS10170
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PCSK1 Human Pre-designed siRNA Set A contains three designed siRNAs for PCSK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-14622AR
CAS No.: 852391-15-2
Synonyms: Necrostatin 1S (Standard); Nec-1S (Standard); 7-Cl-O-Nec1 (Standard)
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Necrostatin 2 (racemate) (Standard) is the analytical standard of Necrostatin 2 (racemate). This product is intended for research and analytical applications. Necrostatin 2 racemate (Nec-1S), the Necrostatin-1 (HY-15760) stable, is a potent and specific RIPK1 inhibitor lacking the IDO-targeting effect [1].
Cat. No.: HY-19943
CAS No.: 1432468-79-5
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TLC388 is a novel camptothecin analog with limited antitumor activity in metastatic NEC .
Cat. No.: HY-RS18538
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Pcsk1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pcsk1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
