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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
Neuroscience
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "Neuroscience" in MCE Product Catalog:
9
9 Cited Publications
Synonyms: NV-5138 hydrochloride
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Mefluleucine (NV-513) hydrochloride, a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. Mefluleucine hydrochloride is used for antidepressant studies .
2
2 Cited Publications
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GNE0877 is a highly selective, orally active and brain-penetrant LRRK2 inhibitor with an IC50 of 3 nM and a Ki of 0.7 nM. GNE0877 can be used for the research of neuroscience .
2
2 Cited Publications
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Dihydrokainic acid is a glutamate transporters (especially GLT1) inhibitor. Dihydrokainic acid targets GLT1 with high affinity, effectively inhibiting its transport function. Dihydrokainic acid exerts its effect by inhibiting the uptake of glutamate, leading to an increase in extracellular glutamate concentration, thereby affecting neuronal excitability and neurotransmission. Dihydrokainic acid is mainly applied in the field of neuroscience for research on glutamate-related neural functions, epilepsy, learning, and memory .
Category:
Alkaloids Neurological Disease Other Alkaloids Endogenous metabolite Disease Research Fields Cancer
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Synonyms: Oregon green 488 succinimidyl ester
Cat. No.: HY-D2906
CAS No.: 1825332-75-9
Cat. No.: HY-W127702
CAS No.: 6106-46-3
Synonyms: Methscopolamine nitrate
Cat. No.: HY-D1401
CAS No.: 195136-52-8
Cat. No.: HY-W127699
CAS No.: 1866-13-3
Synonyms: N,N,N-Trimethyl-2-(propionyloxy)ethanaminium (p-toluenesulfonate)
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ADL-5747 is a selective and orally active agonist of the δ-opioid receptor (DOR). By binding to the δ-opioid receptors, ADL-5747 activates these receptors, thereby playing a role in pain management pathways. ADL-5747 can be used for research into pain management mechanisms .
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4-Chlorophenylguanidine hydrochloride is an urokinase-type plasminogen activator inhibitor. 4-Chlorophenylguanidine hydrochloride is a potent ASIC3 positive allosteric modulator and reverses the effects of ASIC3 desensitization. 4-Chlorophenylguanidine hydrochloride influences ASIC3 activity through directly activating the channel and increasing proton sensitivity. 4-Chlorophenylguanidine hydrochloride offers a chemical backbone for the design of new ASIC3 ligands to study ASIC3 in vivo .
Cat. No.: HY-12237
CAS No.: 20012-10-6
Synonyms: (±)-SKF-38393 hydrobromide
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SKF 38393 ((±)-SKF-38393) hydrobromide is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM .
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L-750667 triHydrochloride is a selective antagonist for the D4 dopamine receptor, with a Ki value of 0.51 nM. The radiolabeled form of L-750667, [ 125I]L-750,667, has a Kd value of 0.16 nM for the D4 receptor. L-750667 triHydrochloride can reverse dopamine-induced inhibition of cAMP accumulation. It can be used to study the distribution and function of D4 dopamine receptors in the central nervous system and has potential applications in the fields of neuroscience and psychiatry .
Cat. No.: HY-P4742A
Synonyms: 6-FAM-AEEAC-SHK TFA
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Cat. No.: HY-P5859
CAS No.: 202075-91-0
Synonyms: α-PMTX
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Cat. No.: HY-106180
CAS No.: 110299-05-3
Synonyms: GR 56072; RG 14202; Selodenoson
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DTI 0009 is a selective adenosine A1 receptor agonist used to reduce heart rate in patients with atrial fibrillation and to treat arrhythmias .
Cat. No.: HY-106933
CAS No.: 118976-38-8
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Dabelotine is an adrenergic receptor agonist used in the study of dementia .
Cat. No.: HY-14793
CAS No.: 327026-93-7
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Lensiprazine is a potent dopamine D2 receptor (D2R) antagonist that acts as a serotonin reuptake inhibitor. Lensiprazine can be used to study bipolar disorder and schizophrenia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
