48 Results for "

Normally

" in MedChemExpress (MCE) Product Catalog:
Products (48)

48 Results for "Normally" in MCE Product Catalog:

35
35 Publications Verification
Cat. No.: HY-P9902A
Synonyms: MK-3475 (anti-PD-1); Lambrolizumab (anti-PD-1)

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Pembrolizumab (anti-PD-1) is a humanized IgG4 antibody and PD-1 inhibitor. Pembrolizumab produces PD-1 blockade, preventing PD-L1 and PD-L2 from connecting to PD-1. This avoids the uncontrolled regulation of T cells on cells that normally express PD-1 .
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31
31 Cited Publications
Cat. No.: HY-17551
CAS No.: 6384-92-5
Synonyms: N-Methyl-D-aspartic acid
NMDA is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.
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3
3 Cited Publications
Cat. No.: HY-P1235A
CAS No.: 1366000-58-9
Synonyms: Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate
Target:  

Endothelin Receptor

Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide acetate inhibits endothelin-1 secretion in a dose-dependent way.
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2
2 Cited Publications
Cat. No.: HY-136886
CAS No.: 172616-80-7
Purity:  96.36%
Synonyms: New Indocyanine Green
IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals .
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2
2 Cited Publications
Cat. No.: HY-114231B
CAS No.: 2244622-33-9
Purity:  ≥98.0%
Synonyms: ELX-02 disulfate; NB-124 disulfate
Target:  

DNA/RNA Synthesis

Research Areas:  

Inflammation/Immunology

Exaluren (ELX-02; NB-124) disulfate is an synthetic eukaryotic ribosome-selective glycoside that induces read-through of nonsense mutations, resulting in normally localized full-length functional proteins. Exaluren disulfate is used for the research of cystic fibrosis caused by nonsense mutations .
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2
2 Cited Publications
Cat. No.: HY-114231
CAS No.: 1375073-93-0
Synonyms: ELX-02; NB-124
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

Exaluren (ELX-02; NB-124) is an synthetic eukaryotic ribosome-selective glycoside that induces read-through of nonsense mutations, resulting in normally localized full-length functional proteins. Exaluren is used for the research of cystic fibrosis caused by nonsense mutations .
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1
1 Cited Publications
Cat. No.: HY-N9457
CAS No.: 60696-62-0
Norcholic acid is a normal minorbile C23 bile acid having four side chain and exsits in human urine and meconium. Norcholic acid can become prominent under certain pathological conditions. Norcholic acid is efficiently absorbed from intestine and quickly excreted into the bile but not into urine .
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Cat. No.: HY-N2514
CAS No.: 14641-93-1
Synonyms: α-D-Lactose
α-Lactose (α-D-Lactose) is the major sugar present in milk. Lactose exists in the form of two anomers, α and β. The α form normally crystallizes as a monohydrate .
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Cat. No.: HY-113367
CAS No.: 60317-54-6
Purity:  99.72%
Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid.
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Cat. No.: HY-173552
CAS No.: 3067681-36-8
Synonyms: KAT-TCIP
Research Areas:  

Cancer

TCIP3 is a bivalent molecular glue degrader that binds dually to p300/CBP and BCL6. TCIP3 redirects p300 and CBP, thereby activating programmed cell death genes that are normally repressed by the oncogenic driver gene BCL6. TCIP3 induces acetylation of BCL6 and histone tails, inhibits c-MYC transcription. TCIP3 can be used for the research of diffuse large B-cell lymphoma (DLBCL) .
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Cat. No.: HY-129738
CAS No.: 868145-09-9
Purity:  99.38%
Target:  

Ras

Research Areas:  

Cardiovascular Disease

I942 is a first in class, selective non-cyclic nucleotide (NCN) EPAC1 agonist. I942 can attenuate proinflammatory cytokine signalling normally associated with cardiovascular diseases .
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Cat. No.: HY-157549A
Synonyms: AYX1 sodium
Research Areas:  

Neurological Disease

Brivoligide (AYX1) sodium is a double-stranded, unprotected, 23 base-pair oligonucleotide. Brivoligide sodium can reduce acute post-surgical pain. Brivoligide sodium mimics the DNA sequence normally bound by EGR1 on chromosomes .
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Cat. No.: HY-P1235
CAS No.: 89213-87-6
Synonyms: Atrial Natriuretic Peptide (ANP) (1-28), human, porcine
Target:  

Endothelin Receptor

Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) inhibits endothelin-1 secretion in a dose-dependent way.
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Cat. No.: HY-P5435
CAS No.: 835653-81-1
Target:  

Ser/Thr Kinase

Research Areas:  

Others

LKBtide is a biological active peptide. (This is a peptide substrate that is phosphorylated by Serine/Threonine kinase 11 (STK11), also known as LKB1. LKBtide is derived from sucrose non-fermenting 1 (SNF1) protein kinase, which is normally activated by the LKB1/AMP-activated protein kinase (AMPK) signaling pathway.)
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Cat. No.: HY-124003
CAS No.: 503-06-0
Phytomonic acid is a long-chain fatty acid containing a cyclopropane ring produced by Lactobacillus reuteri. Lactobacilli that normally produce Lactobacillic acid also have the ability to resist TNF-α .
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Cat. No.: HY-157549
CAS No.: 1803075-42-4
Synonyms: AYX1
Research Areas:  

Neurological Disease

Brivoligide (AYX1) is a double-stranded, unprotected, 23 base-pair oligonucleotide. Brivoligide can reduce acute post-surgical pain. Brivoligide mimics the DNA sequence normally bound by EGR1 on chromosomes .
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Cat. No.: HY-138054
CAS No.: 2171519-89-2
Purity:  ≥99.0%
Target:  

MDM-2/p53

Research Areas:  

Cancer

Cjoc42 is a compound capable of binding to gankyrin. Cjoc42 inhibits gankyrin activity in a dose-dependent manner. Cjoc42 prevents the decrease in p53 protein levels normally associated with high amounts of gankyrin. Cjoc42 restores p53-dependent transcription and sensitivity to DNA damage .
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Cat. No.: HY-N13366
CAS No.: 6712-03-4
3-Methylcrotonyl CoA is a key metabolic intermediate in the leucine degradation pathway, converted to 3-Methylglutaconyl CoA by 3-Methylcrotonyl CoA Carboxylase. Normally, 3-Methylglutaconyl CoA is catalyzed by 3-Methylglutaconyl-CoA Hydratase into 3-Hydroxy-3-methylglutaryl-CoA (HMG CoA). However, mutations in 3-Methylglutaconyl-CoA Hydratase lead to the accumulation of 3-Methylglutaconyl CoA, causing metabolic disorders associated with 3MGA-uria. 3-Methylcrotonyl CoA is useful for research into metabolic diseases related to the leucine degradation pathway .
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Cat. No.: HY-N9457R
CAS No.: 60696-62-0
Ethambutol (dihydrochloride) (Standard) is the analytical standard of Ethambutol (dihydrochloride). This product is intended for research and analytical applications. 0
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Cat. No.: HY-113367S
CAS No.: 2469259-73-0
Purity:  ≥99.0%
Suberylglycine-d4 is the deuterium labeled Suberylglycine. Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid .
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