28 Results for "

OMP

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "OMP" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P99667
CAS No.: 1391727-24-4
Synonyms: OMP-54F28; FZD8-Fc

Target:  

Wnt

Research Areas:  

Cancer

Ipafricept (OMP-54F28; FZD8-Fc) is a first class recombinant fusion protein with the extracellular part of the human frizzled-8 receptor fused to a human IgG1 Fc fragment that binds Wnt ligands, which blocks Wnt signaling. Ipafricept reduces tumor growth and results in a decrease in both liver and lung metastases combined with Gemcitabine (HY-17026) in pancreatic cancer mouse models. Ipafricept shows solid tumor inhibition activity with well tolerance, such as desmoid tumor, germ cell cancer, ovarian cancer .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P9974
CAS No.: 1345009-45-1
Synonyms: OMP-18R5

Target:  

Wnt

Research Areas:  

Cancer

Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to FZD1/2/5/7/8 receptors. Vantictumab can be studied against cancers through direct actions on tumor cells, including CSCs, and effects on the stroma, such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P80369
Synonyms: OMP2, VDAC1, YNL055C, N2441, YNL2441C, POR1, Non-selective voltage-gated ion channel 1, Outer mitochondrial membrane protein porin 1, Voltage-dependent anion-selective channel protein 1, VDAC-1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC, IF-Tissue

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-P99261
CAS No.: 1243262-17-0
Synonyms: OMP 21M18

Target:  

Notch

Research Areas:  

Cancer

Demcizumab (OMP 21M18) is an anti-DLL4 monoclonal antibody. Demcizumab is a potent inhibitor of the Notch pathway. Demcizumab alone or in combination with chemotherapy is effective in various cancer models .
loading...
    loading...
Cat. No.: HY-P99377
CAS No.: 1638338-43-8
Synonyms: OMP-305B83; Anti-DLL4 Reference Antibody (navicixizumab)

Target:  

Notch

Research Areas:  

Cancer

Navicixizumab (OMP-305B83) is a bispecific anti-VEGF and anti-DLL4 inhibitory antibody. Navicixizumab can combine with Paclitaxel (HY-B0015) for cancer research. Navicixizumab can be used in the research of ovarian, primary peritoneal, or fallopian tube cancer .
loading...
    loading...
Cat. No.: HY-P99258
CAS No.: 1447814-75-6
Synonyms: OMP 52M51; Anti-Human NOTCH1 Recombinant Antibody

Target:  

Notch

Research Areas:  

Cancer

Brontictuzumab (OMP 52M51) is a monoclonal antibody (MAb) that inhibits Notch1 signal. Brontictuzumab selectively binds the negative regulatory region of the Notch1. Brontictuzumab inhibits tumor cell proliferation. Brontictuzumab can be used in the research of leukemia and lymphoma .
loading...
    loading...
Cat. No.: HY-P99401
CAS No.: 1684393-04-1
Synonyms: OMP-131R10

Target:  

Wnt

Research Areas:  

Cancer

Rosmantuzumab (OMP-131R10) is an anti-R-spondin 3 (RSPO3) humanized monoclonal antibody. Rosmantuzumab can be used for the research of advanced telapsed and refractory solid tumors .
loading...
    loading...
Cat. No.: HY-P99320
CAS No.: 1359940-55-8
Synonyms: OMP 59R5; Anti-Human NOTCH2 Recombinant Antibody

Target:  

Notch

Research Areas:  

Cancer

Tarextumab (OMP-59R5) is a cross-reactive, fully human IgG2 antibody that selectively inhibits Notch2 and Notch3 signaling. Tarextumab demonstrates broad-spectrum antitumor efficacy in xenograft models of epithelial tumors. Tarextumab can be used for the study of pancreatic cancer .
loading...
    loading...
Cat. No.: HY-P99949
CAS No.: 2044984-83-8
Synonyms: OMP-313M32

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Etigilimab (OMP-313M32), a humanized IgG1 monoclonal antibody, blocks TIGIT interaction with PVR (CD155; poliovirus receptor) and inhibits downstream signalling with target cell killing .
loading...
    loading...
Cat. No.: HY-146412
CAS No.: 2940964-70-3
Purity:  96.20%
Target:  

Pantetheinase

Research Areas:  

Metabolic Disease

Vanin-1-IN-3 (OMP-7) is a vanin-1 inhibitor with an IC50 of 0.038 μM .
loading...
    loading...
Cat. No.: HY-P99876
CAS No.: 2102200-64-4
Synonyms: OMP-336B11

Target:  

Inhibitory Antibodies

Research Areas:  

Others

Efaprimermin alfa (OMP-336B11) is a human monoclonal antibody targeting TNFRSF18. Efaprimermin alfa is a GITR ligand-Fc fusion protein .
loading...
    loading...
Cat. No.: HY-RS09784
Research Areas:  

Others

OMP Human Pre-designed siRNA Set A contains three designed siRNAs for OMP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS16985
Research Areas:  

Others

Omp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Omp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS23428
Research Areas:  

Others

Omp Rat Pre-designed siRNA Set A contains three designed siRNAs for Omp gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-162672
Target:  

Bacterial

Research Areas:  

Infection

Antibacterial agent 231 (derivative 8) is an antimicrobial agent against multidrug-resistant Helicobacter pylori (H. pylori) with a minimum inhibitory concentration of 0.25–0.5 μg/mL. Antibacterial agent 231 directly targets the protein transposase subunit SecA and the outer membrane protein assembly factor BamD to inhibit the trafficking and assembly of bacterial outer membrane proteins (OMPs). Antibacterial agent 231 can be used to study the effects of antibiotic treatment on intestinal microbial balance .
loading...
    loading...
Cat. No.: HY-P73736
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Olfactory marker protein; Olfactory neuronal-specific protein; OMP
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-W826156A
Target:  

Bacterial

Research Areas:  

Infection

6-Aza-UMP disodium is a competitive inhibitor of the OMP decarboxylase domain of UMP synthase (UMP synthase), with a Ki value of 0.51 μM against OMP decarboxylase. 6-Aza-UMP disodium reduces the production of UMP and increases the abundance of OMP. 6-Aza-UMP disodium promotes the formation of toxic 6-aza-UTP, thereby exerting cytotoxicity against bacterial. 6-Aza-UMP disodium can be used in studies related to bacterial infections .
loading...
    loading...
Cat. No.: HY-P705718
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Outer membrane protein OMP38; Outer membrane protein OMPA; AbOMPA; Outer membrane protein OMPAb; OMP38; OMPA
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P704055
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Major outer membrane porin, serovar C; OMPA; OMP1; OMP1C; Major outer membrane porin; serovar C; MOMP
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P704052
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Major outer membrane porin, serovar D; MOMP; OMPA; OMP1; CT_681
Species:  
Source:  
loading...
    loading...