85 Results for "

P19

" in MedChemExpress (MCE) Product Catalog:
Products (85)

85 Results for "P19" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-17447A
CAS No.: 1986-47-6
Synonyms: SKF 385 hydrochloride
Tranylcypromine hydrochloride (SKF 385 hydrochloride) is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1/BHC110) and monoamine oxidase (MAO). Tranylcypromine hydrochloride inhibits LSD1, MAO A and MAO B with IC50s of 20.7, 2.3 and 0.95 μM, respectively. Tranylcypromine hydrochloride can be used for the research of depression .
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1 Cited Publications
Cat. No.: HY-P80615
Synonyms: CDK4 inhibitor p16 INK4 antibody; CDK4I antibody; CDKN2 antibody; CDKN2A antibody; Cell cycle negative regulator beta antibody; CMM2 antibody; Cyclin dependent kinase 4 inhibitor A antibody; Cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4) antibody; Cyclin Dependent Kinase Inhibitor 2A antibody; Cyclin dependent kinase inhibitor 2A isoform 4 antibody; Cyclin dependent kinase inhibitor 2A isoforms 1/2/3 antibody; Cyclin dependent kinase inhibitor p16 antibody; INK4 antibody; INK4A antibody; MLM antibody; MTS1 antibody; Multiple tumor suppressor 1 antibody; p14 antibody; p16 antibody; P16INK4 antibody; p16INK4a antibody; P19 antibody; P19Arf antibody; TP16 antibody;

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse

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1 Cited Publications
Cat. No.: HY-P73195
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL-23 P19/IL-12 p40; IL23; IL-23A; Interleukin 23; SGRF
Species:  
Rat
Source:  
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1 Cited Publications
Cat. No.: HY-P74816
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL-23 P19/IL-12 p40; IL23; IL-23A; Interleukin 23; SGRF
Species:  
Source:  
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1 Cited Publications
Cat. No.: HY-P72785
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cyclin-dependent kinase inhibitor 2A; CDK4I; MTS-1; p16INK4A
Species:  
Source:  
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Cat. No.: HY-P99248
CAS No.: 1612838-76-2
Synonyms: Risankizumab rzaa; BI 655066; ABBV-066

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Risankizumab (BI 655066) is a humanised IgG monoclonal antibody, targeting IL-23 p19 subunit (Kd <10 pM) and inhibiting IL-17 production induced by human IL-23 in mouse splenocytes (IC50 = 2 pM). Risankizumab can be used to research immunological and inflammatory disorders such as psoriasis vulgaris, psoriatic arthritis, generalized pustular psoriasis and erythrodermic psoriasis .
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Cat. No.: HY-P9931
CAS No.: 1350289-85-8
Synonyms: CNTO 1959

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research .
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Cat. No.: HY-P990217

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-Mouse IL-23 p19 Antibody (G23-8) is a rat-derived anti-mouse IL-23 p19 IgG1 monoclonal antibody. Anti-Mouse IL-23 p19 Antibody (G23-8) alleviates inflammation by restoring CLDN8 expression. Anti-Mouse IL-23 p19 Antibody (G23-8) can be used for research on inflammation conditions such as colitis and asthma .
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Cat. No.: HY-P99737
CAS No.: 1884201-71-1
Synonyms: LY­3074828

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Mirikizumab (LY3074828) is a humanized IgG4 monoclonal antibody that targets the p19 subunit of interleukin 23 (IL-23). Mirikizumab binds to human and monkey IL-23 with high affinity, with Kd values of 21 pM and 55 pM, respectively. By inhibiting the binding of IL-23 to IL-23R, Mirikizumab modulates the immune response and holds potential for research in ulcerative colitis and Crohn's disease .
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Cat. No.: HY-P99256
CAS No.: 1326244-10-3
Synonyms: SCH 900222; MK 3222; Anti-Human IL23 Recombinant Antibody

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Tildrakizumab (SCH 900222) is a humanized anti-IL-23 (p19 subunit) monoclonal antibody. IL-23 is a critical cytokine to maintain the Th17 cell phenotype. Tildrakizumab has high-affinity for single-chain IL-23 (Kd: 136 pM). Tildrakizumab is effective against moderate to severe plaque psoriasis .
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Cat. No.: HY-108439
CAS No.: 937807-66-4
Purity:  ≥99.0%
Target:  

Wnt Hedgehog

Research Areas:  

Neurological Disease

Neurodazine is a neurogenic inducer, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways. .
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Cat. No.: HY-10593
CAS No.: 331001-62-8
Purity:  99.13%
Target:  

Wnt

Research Areas:  

Others

IQ 1 is a Wnt/β-catenin/CBP signalling sustainer. IQ 1 maintains long-term expansion of Wnt/β-catenin-driven mouse embryonic stem cells (ESCs) and prevents spontaneous differentiation by enhancing β-catenin/CBP-mediated transcription and preventing conversion to β-catenin/p300-mediated transcription. IQ-1 regulates Wnt signalling by interacting with PR72/130. IQ 1 can be used in study of ESCs expansion .
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Cat. No.: HY-115719
CAS No.: 2755241-73-5
Purity:  99.7%
Target:  

Ser/Thr Kinase

Research Areas:  

Neurological Disease

NR162 is a selective CASK (Ca 2+/calmodulin-dependent Ser/Thr kinase) inhibitor with an IC50 of 80 nM and a Kd of 22 nM. NR162 shows about 50-fold selectivity for CASK than TYRO3. NR162 targets the unique GFG motif of CASK and has excellent shape complementarity to the CASK ATP binding pocket. NR162 can be used for the research of neurological diseases .
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Cat. No.: HY-P99485
CAS No.: 1610353-18-8
Synonyms: AMG 139; MEDI2070

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Brazikumab (AMG 139) is a human IgG2 monoclonal antibody, selectively binds the p19 subunit of IL-23, with a KD of 0.138 nM for human IL-23. Brazikumab can be used for the research of Crohn's disease .
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Cat. No.: HY-117348
CAS No.: 1316652-41-1
Purity:  99.02%
Target:  

HDAC

Research Areas:  

Neurological Disease

NCC-149 is a selective HDAC8 inhibitor and can be used for neural differentiation research .
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Cat. No.: HY-P990057
CAS No.: 2622900-74-5
Synonyms: IBI-112

Target:  

Interleukin Related

Research Areas:  

Cancer

Picankibart is a human-derived IgG1κ antibody targeting IL23A. Picankibart specifically binds to the IL23 p19 subunit and exerts an anti-inflammatory effect by blocking the IL23-mediated signaling pathway.
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Cat. No.: HY-P1494
CAS No.: 57468-17-4
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Substance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.
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Cat. No.: HY-108440
CAS No.: 326886-05-9
Purity:  99.88%
Target:  

Myosin

Research Areas:  

Cardiovascular Disease

Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells .
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Cat. No.: HY-125953
CAS No.: 477243-06-4
Synonyms: Ceramide (Egg, Chicken)
Ceramide (Egg) (Ceramide (Egg, Chicken)) is a ceramide from chicken. Ceramide (Egg) is a sphingomyelin signaling pathway second messenger. Ceramide (Egg) activates PP2A, JNK, p38 MAPK, CAPK, ceramide-activated protein phosphatase, Vav, PKCζ, and SAPK/JNK cascade. Ceramide (Egg) downregulates or inhibits AKT, survivin, CDK2, mTOR, and FLIP. Ceramide (Egg) mediates apoptosis, autophagy, cell cycle arrest, mitochondrial dysfunction, redox state shifts, and ROS generation. Ceramide (Egg) can be used for the research of cancer and neurological disease .
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Cat. No.: HY-P991277
Synonyms: HS-20137

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

QX-004N (HS-20137) is a monoclonal antibody inhibitor targeting the p19 subunit of interleukin-23 (IL-23). QX-004N is promising for research of immune system diseases and diseases of digestive system .
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