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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
PA1
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "PA1" in MCE Product Catalog:
Cat. No.: HY-P10352A
Cat. No.: HY-P10352
CAS No.: 111745-56-3
Synonyms: 16:0-18:1 PA
Cat. No.: HY-125667
CAS No.: 1620951-72-5
Synonyms: Photoamiloride-1
Target:
Research Areas:
PA1 is a photoswitchable epithelial sodium channel (ENaC) blocker. PA1 can switch to cis-PA1 at 400nm and trans-PA1 at 500nm. PA1 inhibits δ/αENaC, αβγENaC, and δβγENaC, with IC50 values of 4.3nM, 90 nM, and 390 nM, respectively [1].
Cat. No.: HY-W725309
CAS No.: 384833-24-3
Synonyms: 1-Stearoyl-2-oleoyl-sn-glycero-3-phosphate sodium
Cat. No.: HY-128850S1
CAS No.: 875654-27-6
Synonyms: N-Acetylmannosamine-13C; ManNAc-13C
Cat. No.: HY-143407
CAS No.: 2882094-29-1
FAK-IN-3 (Compound 36) is a potent inhibitor of focal adhesion kinase (FAK). FAK-IN-3 not only decreases migration and invasion of PA-1 cells, but also reduces expression of MMP-2 and MMP-9. FAK-IN-3 inhibits tumor growth and metastasis, and no obvious adverse effects. FAK-IN-3 has the potential for the research of ovarian cancer [1].
Cat. No.: HY-145486
CAS No.: 799268-65-8
Synonyms: 20:4 Lyso PA
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Research Areas:
1-Arachidonoyl-sn-glycerol 3-phosphate ammonium (20:4 Lyso PA) is a phospholipid and an LPA derived from arachidonic acid. The concentration of 1-Arachidonoyl-sn-glycerol 3-phosphate ammonium in plasma is significantly correlated with the age of onset of cocaine use and the duration of abstinence. 1-Arachidonoyl-sn-glycerol 3-phosphate ammonium can be used in the research of biomarkers for cocaine use disorder (CUD) [1].
Target:
Cat. No.: HY-N15109
CAS No.: 336625-36-6
Category:
Target:
Cat. No.: HY-177497
CAS No.: 2852050-29-2
Target:
Research Areas:
SKLB-03220 is a selective and orally active EZH2 covalent inhibitor with an IC50 of 1.72 nM for EZH2 MUT. SKLB-03220 exhibits weak activities against other tested histone methyltransferases (HMTs) and kinases. SKLB-03220 displays noteworthy potency against ovarian cancer cell lines and induces cell apoptosis. SKLB-03220 significantly inhibits tumor growth in PA-1 xenograft model. SKLB-03220 can be used for the study of ovarian cancer [1].
Cat. No.: HY-128850S5
Synonyms: N-Acetylmannosamine-15N; ManNAc-15N
Cat. No.: HY-W747907
CAS No.: 4753-19-9
Synonyms: β-Pyracin
Category:
Target:
Cat. No.: HY-RS09978
Target:
Research Areas:
PAGR1 Human Pre-designed siRNA Set A contains three designed siRNAs for PAGR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-131574
CAS No.: 31701-88-9
Target:
Target:
Research Areas:
PqsR/LasR-IN-1 (compound 2a) is a potent PqsR and LasR systems inhibitor. PqsR/LasR-IN-1 has anti-virulence activity against Pseudomonas aeruginosa. PqsR/LasR-IN-1 can reduce production of biofilm, pyocyanin, and rhamnolipids in PA .
Cat. No.: HY-128850S2
Synonyms: N-Acetylmannosamine-13C-1; ManNAc-13C-1
Cat. No.: HY-P76724
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PAncreatic alpha-amylase; PA; 1,4-alpha-D-glucan glucanohydrolase
Species:
Source:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
