1 Result for "

PD166326

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PD166326" in MCE Product Catalog:

Cat. No.: HY-118144
CAS No.: 185039-91-2
Purity:  99.99%
Target:  

Src Bcr-Abl p38 MAPK

Research Areas:  

Cancer

PD166326 is an orally active tyrosine kinase inhibitor with a IC50 of 8 nM against abl tyrosine kinase and a IC50 of 6 nM against src tyrosine kinase. PD166326 blocks Bcr/Abl kinase activity. PD166326 inhibits Bcr/Abl-dependent proliferation and cell cycle progression. PD166326 reduces peripheral blood granulocytosis, alleviates splenomegaly and prolongs survival in a mouse model of chronic myeloid leukemia. PD166326 can be used in research related to chronic myeloid leukemia .
loading...
    loading...