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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
PDE9A
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "PDE9A" in MCE Product Catalog:
4
Target:
Research Areas:
Edelinontrine (PF-04447943) is a potent inhibitor of human recombinant PDE9A (IC50=12 nM) with >78-fold selectivity, respectively, over other PDE family members (IC50>1000 nM).
2
2 Cited Publications
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Research Areas:
BAY 73-6691 ((R)-BAY 73-6691) is a potent, brain penetrant, and selective PDE9A inhibitor .
1
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Osoresnontrine (BI-409306) is a potent and selective PDE9A inhibitor, with an IC50 of 52 nM, and shows weak activity against other PDEs, such as PDE1A (IC50, 1.4 µM), PDE1C (IC50, 1.0 µM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A (IC50 all > 10 μM); Osoresnontrine can be used in the research of memory enhancement in CNS disorders.
1
1 Cited Publications
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Research Areas:
BAY-7081, a chemical probe, is a potent, selective, orally active and soluble cyanopyridone-based PDE9A inhibitor with an IC50 of 15 nM .
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Research Areas:
PF-04449613 is a selective PDE9A inhibitor with an IC50 of 22 nM[1]. PF-04449613 improved motor learning ability in a mouse model[2].
Cat. No.: HY-RS10246
Target:
Research Areas:
PDE9A Human Pre-designed siRNA Set A contains three designed siRNAs for PDE9A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10247
Target:
Research Areas:
Pde9a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pde9a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10248
Target:
Research Areas:
Pde9a Rat Pre-designed siRNA Set A contains three designed siRNAs for Pde9a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Research Areas:
(S)-BAY 73-6691 is the isomer of BAY 73-6691 (HY-104028), and can be used as an experimental control. BAY 73-6691 ((R)-BAY 73-6691) is a potent, brain penetrant, and selective PDE9A inhibitor .
Target:
Research Areas:
PDE9-IN-1 is a potent, selective, and orally bioavailable phosphodiesterase-9A (PDE9A) Inhibitor with an IC50 of 8.7 nM .
Cat. No.: HY-P75962
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A; PDE9A
Species:
Source:
Cat. No.: HY-152106B
Purity: 99.06%
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Research Areas:
(±)-BAY-7081 is a racemate of BAY-7081 (HY-152106). BAY-7081 is a potent, selective, orally active and soluble cyanopyridone-based PDE9A inhibitor with an IC50 of 15 nM .
Cat. No.: HY-152106A
Purity: 99.21%
Target:
Research Areas:
(+)-BAY-7081 is an optical isomer of BAY-7081 (HY-152106). BAY-7081 is a potent, selective, orally active and soluble cyanopyridone-based PDE9A inhibitor with an IC50 of 15 nM .
Cat. No.: HY-12788A
Purity: 99.85%
Target:
Research Areas:
(S)-PF-04449613 is the left-handed isomer of PF-04449613 (HY-12788). PF-04449613 is a selective PDE9A inhibitor with an IC50 of 22 nM. PF-04449613 improves motor learning ability in a mouse model .
Cat. No.: HY-104028R
CAS No.: 794568-92-6
Research Areas:
BAY 73-6691 (Standard) is the analytical standard of BAY 73-6691 (HY-104028). This product is intended for research and analytical applications. BAY 73-6691 ((R)-BAY 73-6691) is a potent, brain penetrant, and selective PDE9A inhibitor .
Cat. No.: HY-104028BR
CAS No.: 794568-91-5
Research Areas:
(S)-BAY 73-6691 (Standard) is the analytical standard of (S)-BAY 73-6691 (HY-104028B). This product is intended for research and analytical applications. (S)-BAY 73-6691 is the isomer of BAY 73-6691 (HY-104028), and can be used as an experimental control. BAY 73-6691 ((R)-BAY 73-6691) is a potent, brain penetrant, and selective PDE9A inhibitor .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
