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Results for "

PDI

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PDI (28) Antibiotic (3) Apoptosis (5) Bacterial (3) Biochemical Assay Reagents (1) Endogenous Metabolite (3) Environmental Pollutants (1) Estrogen Receptor/ERR (3) Ferroptosis (3) Glutathione Peroxidase (1) Integrin (1) Isotope-Labeled Compounds (2) MDM-2/p53 (4) Phosphatase (1) PSMA (1) Radionuclide-Drug Conjugates (RDCs) (1) Reactive Oxygen Species (ROS) (3) Reference Standards (3) Sirtuin (3) Small Interfering RNA (siRNA) (7)
By Research Areas:	Cancer (19) Cardiovascular Disease (3) Infection (3) Inflammation/Immunology (4) Metabolic Disease (4) Neurological Disease (10)
Click Chemistry:	Alkynes (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (3) Human Pre-designed siRNA Sets (3) siRNAs (7)

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: PDI

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-107193

Bacitracin 3 Publications Verification	Environmental Pollutants Antibiotic Bacterial PDI	Infection Cancer
Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase (PDI) inhibitor .

HY-W107464

G6PDi-1 Maximum Cited Publications 6 Publications Verification	PDI	Metabolic Disease Inflammation/Immunology
G6PDi-1 is a reversible and non-competitive glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC₅₀ of 0.07 μM for human G6PD. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production in T cells .

HY-100432

LOC14 4 Publications Verification	PDI	Neurological Disease Inflammation/Immunology
LOC14 is a potent Protein disulfide isomerase (PDI) inhibitor with EC₅₀ and K_d values of 500 nM and 62 nM, respectively. LOC14 exhibits high stability in mouse liver microsomes and blood plasma, low intrinsic microsome clearance, and low plasma-protein binding . LOC14 inhibits PDIA3 activity, decreases intramolecular disulfide bonds and subsequent oligomerization (maturation) of HA in lung epithelial cells .

HY-B1228

Ribostamycin sulfate 1 Publications Verification Vistamycin sulfate	Bacterial Antibiotic PDI	Infection
Ribostamycin sulfate (Vistamycin sulfate) is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding, also inhibits the chaperone activity of protein disulfide isomerase (PDI), used in pharmacokinetic and nephrotoxicity studies

HY-100430

CCF642 1 Publications Verification	Apoptosis PDI	Cancer
CCF642 is a potent protein disulfide isomerases (PDI) inhibitor with an IC₅₀ of 2.9 μM. CCF642 causes acute endoplasmic reticulum (ER) stress in multiple myeloma cells accompanied by apoptosis-inducing calcium release. CCF642 has broad anti-multiple myeloma activity .

HY-100433

PACMA 31 5 Publications Verification	PDI	Cancer
PACMA 31 is an irreversible, orally active protein disulfide isomerase (PDI) inhibitor with an IC₅₀ of 10 μM. PACMA 31 forms a covalent bond with the active site cysteines of PDI. PACMA 31 shows tumor targeting ability and significantly suppresses ovarian tumor growth without causing toxicity to normal tissues . PACMA 31 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-114086

ML359	PDI	Cardiovascular Disease
ML359 is a potent, selctive and reversible inhibitor of protein disulfide isomerase (PDI), with an IC₅₀ of 250 nM. ML359 can prevent thrombus formation in vivo .

HY-142127

Ribostamycin 1 Publications Verification Vistamycin; SF-733	Bacterial Antibiotic PDI	Infection
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of *PDI* .

HY-111117

3-Methyltoxoflavin 1 Publications Verification	PDI	Cancer
3-Methyltoxoflavin is a potent Protein disulfide isomerase (PDI) inhibitor, with an IC₅₀ of 170 nM.

HY-N2163

Mudanpioside C	PDI	Cardiovascular Disease
Mudanpioside C is a protein disulfide isomerase (PDI) inhibitor with a human IC₅₀ of 3.31 μM and human K_d of 3.9 μM. Mudanpioside C suppresses collagen-induced platelet aggregation, interferes with platelet activation, adhesion, and spreading. Mudanpioside C can be used for the research of cardiovascular diseases .

HY-117570

KSC-34	PDI	Neurological Disease
KSC-34, a covalent modifier of protein disulfide isomerase A1 (PDIA1), is also a selective and potent a-site inhibitor of PDIA1 with an IC₅₀ of 3.5 μM. KSC-34 displays a 30-fold selectivity for a domain over a′ domain and displays high selectivity for PDIA1 in complex proteomes with minimal engagement of other members of the PDI family . KSC-34 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-124866

PDI-IN-3	PDI	Neurological Disease
PDI-IN-3 (compound 16F16) is a protein disulfide isomerase (PDI) inhibitor. PDI-IN-3 inhibits cell viability .

HY-110172

PDI-IN-1	PDI	Cancer
PDI-IN-1 (Compound P1) is a cell-permeable human protein disulfide isomerase (PDI) inhibitor with an IC₅₀ of 1.7 μM. PDI-IN-1 has anti-cancer activity.

HY-122895

E64FC26 2 Publications Verification	Apoptosis PDI	Cancer
E64FC26 is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC₅₀s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6, respectively. E64FC26 shows anti-myeloma activity .

HY-122895A

(E/Z)-E64FC26	Apoptosis PDI	Cancer
(E/Z)-E64FC26 is a mixture complex of E-E64FC26 and Z-E64FC26. E64FC26 (E-E64FC26) is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC₅₀s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6. E64FC26 shows anti-myeloma activity .

HY-163351

PDI-IN-2	PDI	Cancer
PDI-IN-2 (Compound 22) is a *PDI* or recombinant *PDI* inhibitor with IC₅₀ values of 0.62 and 0.63 μM, respectively. PDI-IN-2 has antitumor activity .

HY-W009300

4-Hydroxyestrone 1 Publications Verification 4-OHE1	Endogenous Metabolite Estrogen Receptor/ERR Sirtuin MDM-2/p53 PDI Ferroptosis Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease Cancer
4-Hydroxyestrone (4-OHE1) is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on *PDI* to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

HY-170655

PDI-IN-4	PDI Integrin	Cardiovascular Disease
PDI-IN-4 (Compound 14d) is an inhibitor of protein disulfide isomerase, with an IC₅₀ value of 0.48 μM. PDI-IN-4 suppresses platelet aggregation and thrombus formation by attenuating GPIIb/IIIa activation without significantly causing cytotoxicity. PDI-IN-4 can be used in research on thrombosis .

HY-RS10265

PDIA2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PDIA2 Human Pre-designed siRNA Set A contains three designed siRNAs for PDIA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDIA2 Human Pre-designed siRNA Set A PDIA2 Human Pre-designed siRNA Set A

HY-RS18780

P4hb Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
P4hb Mouse Pre-designed siRNA Set A contains three designed siRNAs for P4hb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

P4hb Mouse Pre-designed siRNA Set A P4hb Mouse Pre-designed siRNA Set A

HY-RS09945

P4HB Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
P4HB Human Pre-designed siRNA Set A contains three designed siRNAs for P4HB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

P4HB Human Pre-designed siRNA Set A P4HB Human Pre-designed siRNA Set A

HY-P11256

*pDI*	MDM-2/p53	Cancer
pDI is a peptide. pDI inhibits MDM2-p53 and MDMX-p53 interactions with IC₅₀s of 10 and 100 nM respectively. pDI can be used in the research of colorectal cancer .

HY-125832

PBDB-T	Biochemical Assay Reagents	Others
PBDB-T is a wide bandgap polymer donor in Perylene diimide (PDI)-based polymer solar cells (PSCs) .

HY-181574

PDI-IN-5	PDI Glutathione Peroxidase	Neurological Disease Cancer
PDI-IN-5 (compound 30z) is an allosteric-covalent inhibitor targeting protein disulfide isomerase (PDI) with a 2-chloro-pyrrolopyrimidin-4-one scaffold, with an IC₅₀ of 0.4 μM. PDI-IN-5 exhibits selectivity for ERp57 and GPX4, and inhibits glioblastoma. PDI-IN-5 can be used in glioblastoma-related research .

HY-RS09960

PADI1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PADI1 Human Pre-designed siRNA Set A contains three designed siRNAs for PADI1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PADI1 Human Pre-designed siRNA Set A PADI1 Human Pre-designed siRNA Set A

HY-RS10267

Pdia3 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Pdia3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pdia3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pdia3 Mouse Pre-designed siRNA Set A Pdia3 Mouse Pre-designed siRNA Set A

HY-116748

(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane	PDI Phosphatase
(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane is a small-molecule dithiol catalyst with a low thiol pK_a value (8.3) and high reduction potential (-0.24 V), capable of mimicking *PDI* activity. It catalyzes the activation of scrambled ribonuclease A (scrambled ribonuclease A) and promotes the formation of native disulfide bonds, thereby significantly enhancing protein folding efficiency. Adding (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane to the culture medium of Saccharomyces cerevisiae can increase the secretion of exogenously expressed Schizosaccharomyces pombe acid phosphatase by more than threefold. (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane holds great potential for applications in protein production and secretion research .

HY-W009300S

4-Hydroxyestrone-d4 4-OHE1-d₄	Endogenous Metabolite Isotope-Labeled Compounds Estrogen Receptor/ERR Sirtuin MDM-2/p53 PDI Ferroptosis Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease Cancer
4-Hydroxyestrone (4-OHE1)-d₄ is the deuterium labeled 4-Hydroxyestrone (HY-W009300). 4-Hydroxyestrone is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on *PDI* to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

HY-W009300S1

4-Hydroxyestrone-13C6 4-OHE1-¹³C₆	Isotope-Labeled Compounds Endogenous Metabolite Estrogen Receptor/ERR Sirtuin MDM-2/p53 PDI Ferroptosis Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease Cancer
4-Hydroxyestrone (4-OHE1)- ¹³C₆ is a ¹³C-labeled 4-Hydroxyestrone (HY-W009300). 4-Hydroxyestrone is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on *PDI* to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

HY-P11591

PDI2 PSMA-DOTA-PEI2	Radionuclide-Drug Conjugates (RDCs) PSMA	Cancer
PDI2 (PSMA-DOTA-PEI2) is a prostate-specific membrane antigen (PSMA) ligand that acts as a tumor retention agent, renal uptake reducer, imaging agent and antitumor agent, applicable in SPECT diagnostic imaging and radiotheranostics. PDI2 specifically binds to PSMA on prostate cancer cells, enters cells via clathrin-dependent endocytosis, and exhibits higher tumor retention rate and lower renal uptake level. PDI2 is applicable in research related to prostate cancer and castration-resistant metastatic prostate cancer .

HY-N19464

Dicentrinone	PDI	Inflammation/Immunology Cancer
Dicentrinone is an orally active *PDI* inhibitor with an IC₅₀ value of 43.95 μM. Dicentrinone directly binds to PDI and suppresses cell proliferation and reduces cancer cell viability. Dicentrinone elicits anti-inflammatory and antioxidant effects by suppressing leukocyte migration, plasma leakage and paw edema, and scavenging free radicals. Dicentrinone can be used in the research of hepatoma, rheumatism and arthritis .

HY-181573

TC8026	PDI Apoptosis	Neurological Disease Cancer
TC8026 is an allosteric-covalent inhibitor targeting protein disulfide isomerase (PDI), with an IC₅₀ of 7 μM against human *PDI. TC8026 induces endoplasmic reticulum stress-mediated apoptosis. TC8026 is a hit compound with PDI* inhibitory activity identified via high-throughput screening, and it can be used for the research of glioblastoma .

HY-W851050A

BAP2	PDI	Neurological Disease Cancer
BAP2 is an allosteric protein disulfide isomerase (PDI) inhibitor with a IC₅₀ of 0.85 μM. BAP2 binds to His256 in the b′ domain of *PDI* and exerts inhibitory effects through allosteric binding to the b′ domain. BAP2 upregulates GRP78. BAP2 inhibits the growth of glioblastoma cells. BAP2 can be used in studies related to glioblastoma .

HY-100430R

CCF642 (Standard)	Apoptosis Reference Standards PDI	Cancer
CCF642 (Standard) is the analytical standard of CCF642 (HY-100430). This product is intended for research and analytical applications. CCF642 is a potent protein disulfide isomerases (PDI) inhibitor with an IC50 of 2.9 μM. CCF642 causes acute endoplasmic reticulum (ER) stress in multiple myeloma cells accompanied by apoptosis-inducing calcium release. CCF642 has broad anti-multiple myeloma activity .

HY-RS25269

P4hb Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
P4hb Rat Pre-designed siRNA Set A contains three designed siRNAs for P4hb gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

P4hb Rat Pre-designed siRNA Set A P4hb Rat Pre-designed siRNA Set A

HY-RS18831

Padi2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Padi2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Padi2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Padi2 Mouse Pre-designed siRNA Set A Padi2 Mouse Pre-designed siRNA Set A

HY-100433R

PACMA 31 (Standard)	PDI Reference Standards	Cancer
PACMA 31 (Standard) is the analytical standard of PACMA 31 (HY-100433). This product is intended for research and analytical applications. PACMA 31 is an irreversible, orally active protein disulfide isomerase (PDI) inhibitor with an IC50 of 10 μM. PACMA 31 forms a covalent bond with the active site cysteines of PDI. PACMA 31 shows tumor targeting ability and significantly suppresses ovarian tumor growth without causing toxicity to normal tissues . PACMA 31 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-100432R

LOC14 (Standard)	PDI Reference Standards	Neurological Disease Inflammation/Immunology
LOC14 (Standard) is the analytical standard of LOC14 (HY-100432). This product is intended for research and analytical applications. LOC14 is a potent Protein disulfide isomerase (PDI) inhibitor with EC50 and Kd values of 500 nM and 62 nM, respectively. LOC14 exhibits high stability in mouse liver microsomes and blood plasma, low intrinsic microsome clearance, and low plasma-protein binding . LOC14 inhibits PDIA3 activity, decreases intramolecular disulfide bonds and subsequent oligomerization (maturation) of HA in lung epithelial cells .

Cat. No.	Product Name	Target	Research Area

HY-P11256

*pDI*	MDM-2/p53	Cancer
pDI is a peptide. pDI inhibits MDM2-p53 and MDMX-p53 interactions with IC₅₀s of 10 and 100 nM respectively. pDI can be used in the research of colorectal cancer .

HY-P11591

PDI2 PSMA-DOTA-PEI2	Radionuclide-Drug Conjugates (RDCs) PSMA	Cancer
PDI2 (PSMA-DOTA-PEI2) is a prostate-specific membrane antigen (PSMA) ligand that acts as a tumor retention agent, renal uptake reducer, imaging agent and antitumor agent, applicable in SPECT diagnostic imaging and radiotheranostics. PDI2 specifically binds to PSMA on prostate cancer cells, enters cells via clathrin-dependent endocytosis, and exhibits higher tumor retention rate and lower renal uptake level. PDI2 is applicable in research related to prostate cancer and castration-resistant metastatic prostate cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-107193

Bacitracin 3 Publications Verification	Structural Classification Classification of Application Fields Anti-aging Anti-parasitic Antibacterial Disease Research Other Antibiotics Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Disease Research Fields Source Classification Cancer	Environmental Pollutants Antibiotic Bacterial PDI
Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase (PDI) inhibitor .

HY-B1228

Ribostamycin sulfate 1 Publications Verification Vistamycin sulfate	Infection Microorganisms Classification of Application Fields Antibiotics Resistance Selection Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic PDI
Ribostamycin sulfate (Vistamycin sulfate) is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding, also inhibits the chaperone activity of protein disulfide isomerase (PDI), used in pharmacokinetic and nephrotoxicity studies

HY-142127

Ribostamycin 1 Publications Verification Vistamycin; SF-733	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic PDI
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of *PDI* .

HY-N2163

Mudanpioside C	Structural Classification Other Monoterpenes Monophenols other families Classification of Application Fields Terpenoids Other Diseases Phenols Plants Disease Research Fields Source Classification	PDI
Mudanpioside C is a protein disulfide isomerase (PDI) inhibitor with a human IC₅₀ of 3.31 μM and human K_d of 3.9 μM. Mudanpioside C suppresses collagen-induced platelet aggregation, interferes with platelet activation, adhesion, and spreading. Mudanpioside C can be used for the research of cardiovascular diseases .

HY-W009300

4-Hydroxyestrone 1 Publications Verification 4-OHE1	Structural Classification Animals Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite Estrogen Receptor/ERR Sirtuin MDM-2/p53 PDI Ferroptosis Reactive Oxygen Species (ROS)
4-Hydroxyestrone (4-OHE1) is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on *PDI* to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

HY-N19464

Dicentrinone	Structural Classification Alkaloids Duguetia surinamensis R.E.Fr. Quinoline Alkaloids Plants Annonaceae Source Classification	PDI
Dicentrinone is an orally active *PDI* inhibitor with an IC₅₀ value of 43.95 μM. Dicentrinone directly binds to PDI and suppresses cell proliferation and reduces cancer cell viability. Dicentrinone elicits anti-inflammatory and antioxidant effects by suppressing leukocyte migration, plasma leakage and paw edema, and scavenging free radicals. Dicentrinone can be used in the research of hepatoma, rheumatism and arthritis .

Species:	Human (8) Mouse (3) Cynomolgus (2)
Tag:	His (12) GST (1)
Source:	HEK293 (5) sf9 insect cells (1) Sf9 insect cells (2) E. coli (4) sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71087

	P4HB Protein, Human (HEK293, His) Protein Disulfide-Isomerase; PDI; Cellular Thyroid Hormone-Binding Protein; Prolyl 4-Hydroxylase Subunit Beta; p55; P4HB; ERBA2L; PDI; PDIA1; PO4DB	Human	HEK293
	The P4HB protein is a multifunctional entity that catalyzes disulfide bonding processes at the cell surface and within cells. As a reductase, it modifies outer surface proteins and participates in the formation of disulfide bonds in nascent proteins. P4HB Protein, Human (HEK293, His) is the recombinant human-derived P4HB protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P704834

	PAD1 Protein, Human (sf9, His) PAD1; PDI1	Human	sf9 insect cells
	PAD1 Protein, Human (sf9, His) is the recombinant human-derived PAD1 protein, expressed by sf9 insect cells, with N-His tag.

HY-P703022

	PAD1 Protein, Human (Active, sf9, GST) PAD1; PDI1	Human	Sf9 insect cells
	PAD1 Protein, Human (Active, sf9, GST) is the recombinant human-derived PAD1, expressed by Sf9 insect cells , with GST labeled tag. ,

HY-P78738

	PADI2 Protein, Human (HEK293, His) PADI2; PAD-H19; KIAA0994; PAD2; PDI2	Human	HEK293
	The PADI2 protein serves as a catalyst for the deimination process, specifically targeting arginine residues within proteins and facilitating their conversion. PADI2 Protein, Human (HEK293, His) is the recombinant human-derived PADI2 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P78767

	PADI2 Protein, Mouse (HEK293, His) PADI2; PAD-H19; KIAA0994; PAD2; PDI2	Mouse	HEK293
	Padi2 Protein functions as an enzyme that catalyzes the deimination process, specifically targeting arginine residues within proteins. PADI2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PADI2 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P78575

	PADI2 Protein, Cynomolgus (sf9, His) PADI2; PAD-H19; KIAA0994; PAD2; PDI2	Cynomolgus	sf9 insect cells
	The PADI2 protein plays a key role in cellular processes by catalyzing the deimination of protein arginine residues. This enzymatic activity, called citrullination, involves the conversion of arginine to citrulline, affecting the structure and function of the target protein. PADI2 Protein, Cynomolgus (sf9, His) is the recombinant cynomolgus-derived PADI2 protein, expressed by sf9 insect cells , with N-His labeled tag.

HY-P704161

	PADI3 Protein, Human (sf9, His) PAD3; PDI3; UHS1; Protein-arginine deiminase type-3	Human	Sf9 insect cells
	PADI3 Protein, Human (sf9, His) is the recombinant human-derived PADI3 protein, expressed by Sf9 insect cells, with N-His tag.

HY-P78767A

	PADI2 Protein, Mouse (HEK293, N-His) PADI2; PAD-H19; KIAA0994; PAD2; PDI2	Mouse	HEK293
	Padi2 Protein functions as an enzyme that catalyzes the deimination process, specifically targeting arginine residues within proteins. PADI2 Protein, Mouse (HEK293, N-His) is the recombinant mouse-derived PADI2, expressed by HEK293, with N-10*His labeled tag.

HY-P74658

	P4HB Protein, Mouse (HEK293, His) Protein disulfide-isomerase; PDI; ERp59; p55; P4HB; PDIa1	Mouse	HEK293
	P4HB proteins are versatile and multifunctional, coordinating disulfide bond catalysis at the cell surface and inside the cell.It exhibits reductase activity, cleaves disulfide bonds, induces structural modifications, and functions as a chaperone to inhibit aggregation of misfolded proteins.P4HB Protein, Mouse (HEK293, His) is the recombinant mouse-derived P4HB protein, expressed by HEK293 , with C-His labeled tag.

HY-P71917

	P4HB Protein, Human (His) 1 Publications Verification Cellular thyroid hormone binding protein; Cellular thyroid hormone-binding protein; Collagen prolyl 4 hydroxylase beta; Disulphide Isomerase; DSI; EC 5.3.4.1; ER protein 59; ERBA2L; ERp59; GIT; P4HB; P4Hbeta; p55; PDI; PDIA1; PDIA1_HUMAN; PDIR; PHDB; PO4DB; PO4HB; PROHB; Protocollagen hydroxylase; Thbp;	Human	E. coli
	The P4HB protein is a multifunctional entity that catalyzes disulfide bonding processes at the cell surface and within cells. As a reductase, it modifies outer surface proteins and participates in the formation of disulfide bonds in nascent proteins. P4HB Protein, Human (His) is the recombinant human-derived P4HB protein, expressed by E. coli , with N-6*His labeled tag.

HY-P701030

	PADI4 Protein, Human (Biotinylated, His) Protein-arginine deiminase type-4; HL-60 PAD; HL60 PAD; HL-60; PAD; PAD4; PADI5; PDI5	Human	E. coli
	The PADI4 protein catalyzes the citrullination of arginine residues in proteins such as histones, contributing to the histone code and stem cell regulation. PADI4 Protein, Human (Biotinylated, His) is the recombinant human-derived PADI4 protein, expressed by E. coli , with N-His labeled tag.

HY-P70990

	PADI4 Protein, Human (His) 1 Publications Verification Protein-Arginine Deiminase Type-4; HL-60 PAD; Peptidylarginine Deiminase IV; Protein-arginine Deiminase type IV; PADI4; PADI5; PDI5	Human	E. coli
	PADI4 is a hydrolase that converts arginine residues in histones to citrulline. PADI4 promotes tumor progression by up-regulating the cytokine receptor CXCR2. PADI4 can also cause inflammation and immune responses. PADI4 Protein, Human (His) is the recombinant human-derived PADI4 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P703812

	PADI4 Protein, Cynomolgus (His) Protein-Arginine Deiminase Type-4; HL-60 PAD; Peptidylarginine Deiminase IV; Protein-arginine Deiminase type IV; PADI4; PADI5; PDI5	Cynomolgus	E. coli
	PADI4 Protein, Cynomolgus (His) is the recombinant cynomolgus-derived PADI4 protein, expressed by E. coli, with N-His tag.

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HY-W009300S

4-Hydroxyestrone-d4

4-Hydroxyestrone (4-OHE1)-d₄ is the deuterium labeled 4-Hydroxyestrone (HY-W009300). 4-Hydroxyestrone is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on PDI to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

HY-W009300S1

4-Hydroxyestrone-13C6

4-Hydroxyestrone (4-OHE1)- ¹³C₆ is a ¹³C-labeled 4-Hydroxyestrone (HY-W009300). 4-Hydroxyestrone is a brain-penetrant estrogen metabolite. 4-Hydroxyestrone shows neuroprotective effects involving increased cytoplasmic localization of p53 resulting from SIRT1-mediated p53 deacetylation. 4-Hydroxyestrone relies on PDI to mediate its protective effect against chemically induced ferroptosis in estrogen receptor-negative cancer cells. 4-Hydroxyestrone inhibits lipid peroxidation and lipid-ROS accumulation. 4-Hydroxyestrone blocks preovulatory luteinizing hormone surges in Rattus norvegicus. 4-Hydroxyestrone can be used for the researches of neurodegeneration, breast cancer and endocrine disease .

Host:	Mouse (4) Rabbit (3)
Reactivity:	Human (7) Rat (3) Mouse (3)
Application:	IHC-P (7) ICC/IF (5) IHC-F (2) WB (7) FC (4) ELISA (4)
Isotype:	IgG (3) IgG2a (4)
Conjugation:	Non-conjugated (7) Biotin (1)
Clonality:	Monoclonal (4) Recombinant (2)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81758

	P4HB Antibody (YA1503) P4HB; DSI; ERBA2L; GIT; P4Hbeta; PDI; PDIA1; PHDB; PO4DB; PO4HB; PROHB	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	P4HB Antibody (YA1503) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to P4HB.

HY-P81758A

	P4HB Antibody (YA1503)(PBS only) P4HB; DSI; ERBA2L; GIT; P4Hbeta; PDI; PDIA1; PHDB; PO4DB; PO4HB; PROHB	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	P4HB Antibody (YA1503) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to P4HB.

HY-P82048

	ERp29 Antibody (YA1793) ERp28; ERP29_HUMAN; ERp31; HEL S 107; PDI-DB; PDIA9	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	ERp29 Antibody (YA1793) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ERp29.

HY-P83984

	P4HB Antibody (YA3681) DSI,GIT,PDI,PHDB,PDIA1,PO4DB,PO4HB,PROHB,CLCRP1,ERBA2L,P4Hbeta	WB, IHC-P, FC, ELISA	Human
	P4HB Antibody (YA3681) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to P4HB.

HY-P83985

	P4HB Antibody (YA3682) DSI,GIT, PDI,PHDB, PDIA1,PO4DB, PO4HB,PROHB,CLCRP1, ERBA2L,P4Hbeta	WB, IHC-P, ICC/IF, FC, ELISA	Human
	P4HB Antibody (YA3682) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to P4HB.

HY-P83984A

	P4HB Antibody (YA3681)(PBS only) DSI,GIT,PDI,PHDB,PDIA1,PO4DB,PO4HB,PROHB,CLCRP1,ERBA2L,P4Hbeta	WB, IHC-P, FC, ELISA	Human
	P4HB Antibody (YA3681) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to P4HB.

HY-P83985A

	P4HB Antibody (YA3682)(PBS only) DSI,GIT, PDI,PHDB, PDIA1,PO4DB, PO4HB,PROHB,CLCRP1, ERBA2L,P4Hbeta	WB, IHC-P, ICC/IF, FC, ELISA	Human
	P4HB Antibody (YA3682) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to P4HB.