7 Results for "

PRI

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "PRI" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-112045
CAS No.: 1422253-38-0
Purity:  99.56%
Synonyms: PRI-724
Target:  

Wnt

Research Areas:  

Cancer

PRI-724 is a selective inhibitor of the CBP/β-catenin interaction.
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Cat. No.: HY-15266
CAS No.: 112827-99-3
Synonyms: PRI 2202; Impurity D of Calcipotriol
Target:  

Drug Derivative VD/VDR

Research Areas:  

Cancer

24R-Calcipotriol (PRI 2202; Impurity D of Calcipotriol), an isomer of Calcipotriol (HY-10001), is a synthetic vitamin D analog. 24R-Calcipotriol exhibits synergistic antiproliferative effects with low-dose cytostatics in in vitro. 24R-Calcipotriol produces tumor growth inhibition when combined with Cyclophosphamide (HY-17420) and Cisplatin (HY-17394) in mice models. 24R-Calcipotriol can increase serum calcium levels and reduce blood leukocyte counts . 24R-Calcipotriol can be used for the research of mammary cancer and Lewis lung cancer .
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Cat. No.: HY-B1448A
CAS No.: 105979-17-7
Synonyms: KW-3049 free base
Research Areas:  

Cardiovascular Disease

Benidipine is a potent and orally active calcium channel antagonist . Benidipine shows anti-apoptosis effects in ischaemic/reperfused myocardial cells . Benidipine increases the activity of endothelial cell-type nitric oxide synthase and improves coronary circulation in hypertensive rats .
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Cat. No.: HY-135276
CAS No.: 1655508-14-7
Target:  

MicroRNA Apoptosis

Research Areas:  

Cancer

Targaprimir-96 is a potent inhibitor of microRNA-96 (miR-96) processing. Targaprimir-96 selectively modulates miR-96 production in cancer cells and triggers apoptosis. Targaprimir-96 binds primary miR-96 (pri-miR-96) with low nanomolar affinity. Targaprimir-96 directly engages pri-miR-96 in breast cancer cells and is ineffective on healthy breast cells .
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Cat. No.: HY-135276A
Target:  

MicroRNA Apoptosis

Research Areas:  

Cancer

Targaprimir-96 TFA is a potent inhibitor of microRNA-96 (miR-96) processing. Targaprimir-96 TFA selectively modulates miR-96 production in cancer cells and triggers apoptosis. Targaprimir-96 TFA binds primary miR-96 (pri-miR-96) with low nanomolar affinity. Targaprimir-96 TFA directly engages pri-miR-96 in breast cancer cells and is ineffective on healthy breast cells .
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Cat. No.: HY-166525S
Synonyms: PRI 2202-d4; Impurity D of Calcipotriol-d4
24R-Calcipotriol-d4 (PRI 2202-d4; Impurity D of Calcipotriol-d4) is the deuterium labeled 24R-Calcipotriol. 24R-Calcipotriol is an impurity of Calcipotriol. Calcipotriol is a ligand of VDR-like receptors.
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Cat. No.: HY-D3330
APC-Cy7 is an APC-tandem fluorochrome (allophycocyanin-cyanine 7) and degradable fluorochrome, with maximum absorption at ~650 nm, peak emission at 767 nm when excited by a 633 nm red laser, and cell-dependent degradation. APC-Cy7 undergoes time-dependent degradation (decoupling) when bound to peripheral blood leukocytes, leading to nonspecific APC channel signal, with degradation cell type-dependent. APC-Cy7 shows reduced degradation when immunolabeled cells have inhibited metabolic activity or are incubated with vitamin C. APC-Cy7 serves as a tandem fluorochrome in multiparametric flow cytometry for detection of leukocyte surface proteins when conjugated to specific antibodies (Ex/Em = 650 nm/778 nm) .
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