Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
Peptidylarginine deiminase
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "Peptidylarginine deiminase" in MCE Product Catalog:
57
57 Publications Verification
Target:
Research Areas:
GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably lower potency (250 nM) is observed.
1
1 Cited Publications
Synonyms: Theophyllineacetic acid; Theophylline-7-acetic acid
1
1 Cited Publications
Cat. No.: HY-P70990
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI4; Protein-Arginine deiminase Type IV; Prev. PADI5; HL-60 PAD; PDI5; PAD4; PDI4; Peptidyl Arginine deiminase Type IV; PAD; Peptidylarginine deiminase IV; Peptidyl Arginine deiminase, Type IV; PADI-H Protein; Peptidyl Arginine deiminase, Type V; PADI4
Species:
Human
Source:
E. coli
Target:
Research Areas:
BMS-P5 is a selective and orally active peptidylarginine deiminase 4 (PAD4) inhibitor with an IC50 of 98 nM. BMS-P5 shows selective for PAD4 over PAD1, PAD2, and PAD3. BMS-P5 blocks multiple myeloma (MM)-induced neutrophil extracellular trap (NET) formation and delays progression of MM in a syngeneic mouse model .
Target:
Research Areas:
BMS-P5 free base is a selective and orally active peptidylarginine deiminase 4 (PAD4) inhibitor with an IC50 of 98 nM. BMS-P5 free base shows selective for PAD4 over PAD1, PAD2, and PAD3. BMS-P5 free base blocks multiple myeloma (MM)-induced neutrophil extracellular trap (NET) formation and delays progression of MM in a syngeneic mouse model .
Cat. No.: HY-P2966
CAS No.: 75536-80-0
Target:
Research Areas:
Protein-arginine deiminase is a unique family of enzymes that catalyzes the hydrolysis of peptidyl-arginine to form peptidyl-citrulline .
Cat. No.: HY-B1505A
CAS No.: 18833-13-1
Synonyms: Theophyllineacetic acid piperazine; Theophylline-7-acetic acid piperazine
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Acefylline (Theophyllineacetic acid) piperazine, a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline piperazine is a peptidylarginine deiminase (PAD) activator. Acefylline piperazine is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline piperazine can be used in asthma research .
Synonyms: Theophyllineacetic acid (Standard); Theophylline-7-acetic acid (Standard)
Cat. No.: HY-175518
Target:
Research Areas:
PADI4-IN-1 is a potent peptidylarginine deiminase isoform 4 (PADI4) inhibitor with an IC50 of 1.5 μM and SI (PADI1/PADI4) of 52.1. PADI4-IN-1 can inhibit cellular citrullination events. PADI4-IN-1 can be used for the research of inflammation, such as rheumatoid arthritis .
Cat. No.: HY-E70954
Target:
Research Areas:
Peptidyl Arginine Deiminase, Rabbit (EC 3.5.3.15) is the enzyme that converts arginine into citrulline. Calcium is required for peptidylarginine deiminase activity in vitro.
Cat. No.: HY-P703052
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI6; Protein-Arginine deiminase Type VI; Peptidyl Arginine deiminase 6; Peptidylarginine deiminase Type 6; Inactive Protein-Arginine deiminase Type-6; Peptidylarginine deiminase VI; Peptidyl Arginine deiminase-Like Protein; OZEMA16; Peptidyl Arginine De
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704835
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PADI6; Protein-Arginine deiminase Type VI; Peptidyl Arginine deiminase 6; Peptidylarginine deiminase Type 6; Inactive Protein-Arginine deiminase Type-6; Peptidylarginine deiminase VI; Peptidyl Arginine deiminase-Like Protein; OZEMA16; Peptidyl Arginine De
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P704834
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI1; PDI; Peptidyl Arginine deiminase 1; Peptidyl Arginine deiminase, Type I; PDI1; Protein-Arginine deiminase Type I; PAD1; Peptidylarginine deiminase I; Protein-Arginine deiminase Type-1; HPAD-Colony 10; HPAD10; Peptidylarginine deiminase Type I
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P703022
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI1; PDI; Peptidyl Arginine deiminase 1; Peptidyl Arginine deiminase, Type I; PDI1; Protein-Arginine deiminase Type I; PAD1; Peptidylarginine deiminase I; Protein-Arginine deiminase Type-1; HPAD-Colony 10; HPAD10; Peptidylarginine deiminase Type I
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704161
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI3; Protein-Arginine deiminase Type-3; Peptidyl Arginine deiminase 3; Peptidylarginine deiminase III; PDI3; PAD3; Peptidyl Arginine deiminase, Type III; UHS1; Protein-Arginine deiminase Type III
Species:
Human
Source:
Sf9 insect cells
Synonyms: Theophyllineacetic acid (GMP); Theophylline-7-acetic acid (GMP)
Cat. No.: HY-P78738
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PADI2; Protein-Arginine deiminase Type-2; Peptidyl Arginine deiminase 2; PAD-H19; PDI2; PAD2; KIAA0994; CDNA FLJ61278, Highly Similar To Protein-Arginine deiminase Type-2; Peptidyl Arginine deiminase, Type II; Peptidylarginine deiminase II; Protein-Argini
Species:
Human
Source:
HEK293
Cat. No.: HY-P78767
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PADI2; Protein-Arginine deiminase Type-2; Peptidyl Arginine deiminase 2; PAD-H19; PDI2; PAD2; KIAA0994; CDNA FLJ61278, Highly Similar To Protein-Arginine deiminase Type-2; Peptidyl Arginine deiminase, Type II; Peptidylarginine deiminase II; Protein-Argini
Species:
Mouse
Source:
HEK293
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
