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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
Pioglitazone
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "Pioglitazone" in MCE Product Catalog:
50
50 Publications Verification
Synonyms: U 72107
Target:
Research Areas:
Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone can be used in diabetes research .
50
50 Publications Verification
Synonyms: U 72107A; AD 4833
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Research Areas:
Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC50s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
Cat. No.: HY-14601R
CAS No.: 112529-15-4
Synonyms: U 72107A (Standard); AD 4833 (Standard)
Target:
Research Areas:
Pioglitazone (hydrochloride) (Standard) is the analytical standard of Pioglitazone (hydrochloride). This product is intended for research and analytical applications. Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC50s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
Cat. No.: HY-13956R
CAS No.: 111025-46-8
Synonyms: U 72107 (Standard)
Target:
Cat. No.: HY-13956B
CAS No.: 1266523-09-4
Synonyms: U 72107 potassium
Target:
Research Areas:
Pioglitazone (U 72107) potassium is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 μM and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone potassium can be used in diabetes research .
Cat. No.: HY-13956C
CAS No.: 959687-65-1
Synonyms: (R)-U 72107
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Research Areas:
(R)-Pioglitazone ((+)-pioglitazone) is the R enantiomer of Pioglitazone (HY-13956). (R)-Pioglitazone is an orally active and selective peroxisome proliferator-activated receptor (PPARγ) agonist with high affinity binding to the PPARγ ligand-binding domain. (R)-Pioglitazone can be used for the research of Alzheimer's disease .
Cat. No.: HY-119311
CAS No.: 146062-45-5
Target:
Research Areas:
Pioglitazone ketone is an active metabolite of the PPARγ agonist Pioglitazone (HY-13956). Formation of pioglitazone ketone occurs primarly through cytochrome P450 (CYP) isoform CYP2C8-mediated metabolism of pioglitazone. Pioglitazone ketone (100 mg/kg in the diet) reduces blood glucose levels in a KKAy mouse model of type 2 diabetes.
Cat. No.: HY-132468S
CAS No.: 1185033-84-4
Cat. No.: HY-144145S
CAS No.: 2747917-81-1
Synonyms: U 72107-d4
Cat. No.: HY-W738533
Synonyms: U 72107A-d4; AD 4833-d4
Cat. No.: HY-132379S
CAS No.: 1189445-29-1
Synonyms: MIN-102-d5; HydroxyPioglitazone-d5
Cat. No.: HY-13956A
CAS No.: 1259828-75-5
Synonyms: (R)-U 72107-d1
Cat. No.: HY-176214
Research Areas:
PPARγ agonist 19 (Compound 5e) is a PPARγ agonist. PPARγ agonist 19 has an IC50 of 11.27 μM against COX-1 and an IC50 of 0.05 μM against COX-1. PPARγ agonist 19 increases glucose uptake in rat hemidiaphragm assay and is superior to pioglitazone (HY-13956). PPARγ agonist 19 alleviates hyperglycemia and insulin resistance in an in vivo model of type 2 diabetes in rats and protects against renal and lipidemia damage caused by metabolic dysfunction .
Cat. No.: HY-123974
CAS No.: 2252478-54-7
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Research Areas:
BR101549 is a non-TZD agonist of PPARγ. BR101549 activates PPARγ to the level of Pioglitazone in vitro. BR101549 can control blood glucose level in mouse model. BR101549 can be studied in anti-diabetic research .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
