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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
558 Results for "
Protein Kinase B
" in MedChemExpress (MCE) Product Catalog:
Products (558)
558 Results for "Protein Kinase B" in MCE Product Catalog:
49
49 Publications Verification
Synonyms: Mitozantrone; NSC 301739
Category:
Target:
49
49 Publications Verification
Synonyms: Mitozantrone dihydrochloride; NSC 301739 dihydrochloride
14
14 Cited Publications
OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC50 of 28 nM . OTS964 hydrochloride is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM .
9
9 Cited Publications
Target:
Research Areas:
NSC 95397 is a potent, selective Cdc25 dual specificity phosphatase inhibitor (Ki=32 nM (Cdc25A), 96 nM (Cdc25B), 40 nM (Cdc25C); IC50=22.3 nM (human Cdc25A), 56.9 nM (human Cdc25C), 125 nM (Cdc25B)) . NSC 95397 inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) and suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and ERK1/2 pathway .
4
4
4
4 Cited Publications
Cat. No.: HY-P700583
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: JAK1; JTK3; Prev. JAK1B; JAK1 Protein; JAK1A; AIIDE; Tyrosine-Protein Kinase JAK1; JAK-1; Janus Kinase 1; Tyrosine-Protein Kinase
Species:
Human
Source:
P. pastoris
4
Category:
Alkaloids Rutaceae Quinoline Alkaloids Plants Skimmia reevesiana Fort. Disease Research Fields Inflammation/Immunology
Target:
4
4 Cited Publications
Cat. No.: HY-P80276
Synonyms: AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; MGC99656 antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein Kinase B Alpha antibody; Protein Kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; RAC-alpha serine/threonine-Protein Kinase antibody; RAC-PK-alpha antibody;
4
4 Cited Publications
Cat. No.: HY-P80728
Synonyms: AI849689 antibody;
c Jun N terminal Kinase 1 antibody;
C-JUN Kinase 1 antibody;
c-Jun N-terminal Kinase 1 antibody;
EC 2.7.11.24 antibody;
JNK 1 antibody;
JNK antibody;
JNK-46 antibody;
JNK1A2 antibody;
JNK21B1/2 antibody;
MAP Kinase 8 antibody;
MAPK 8 antibody;
mapk8 antibody;
Mitogen activated Protein Kinase 8 antibody;
MK08_HUMAN antibody;
p54 gamma antibody;
Prkm8 antibody;
Protein Kinase JNK1 antibody;
Protein Kinase, mitogen-activated, 8 antibody;
SAPK 1 antibody;
SAPK gamma antibody;
SAPK1 antibody;
Stress-activated Protein Kinase 1 antibody
4
Lestaurtinib (CEP-701) is an orally active and selective RPTKs (receptor protein tyrosine kinase) inhibitor, competitively inhibits ATP binding to the TrkA/B/C domain. Lestaurtinib inhibits RPTKs phosphorylation, with IC50s of 2, 25 and 0.9 nM for FLT3, TrkA and JAK2, respectively. Lestaurtinib induces apoptosis and cycle arrest, also can inhibit growth of tumor .
2
2
2
Purvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC50s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC50>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum .
2
2 Cited Publications
Cat. No.: HY-P80445
Synonyms: Alpha CaMKII; Calcium calmodulin dependent Protein Kinase II; Calcium/calmodulin dependent Protein Kinase II alpha B subunit; Calcium/calmodulin dependent Protein Kinase type II alpha chain; Calcium/calmodulin-dependent Protein Kinase (CaM Kinase) II alpha; Calcium/calmodulin-dependent Protein Kinase II alpha; Calcium/calmodulin-dependent Protein Kinase II-alpha; Calcium/calmodulin-dependent Protein Kinase type II subunit alpha; Calcium/calmodulin-dependent Protein Kinase type IIA; CaM Kinase II alpha chain; CaM Kinase II alpha subunit; CaM Kinase II subunit alpha; CaMK II alpha subunit; CaMK-II subunit alpha; Camk2a; CAMKA; CaMKII; CaMKIINalpha; EC2.7.11.17; KCC2A_HUMAN; KIAA0968; MGC123320; MGC139375; MGC155201; mKIAA0968; PK2CDD; PKCCD; R74975; zgc:112538; zgc:123320;
2
Target:
Research Areas:
Zabedosertib (BAY 1834845) is a selective, orally active IRAK4 inhibitor with immunomodulatory potential, IC50 is 3.55 nM. IRAK4 is a protein kinase involved in signaling innate immune responses from Toll-like receptors . Zabedosertib exhibits anti-inflammatory property against IL-β, LPS (HY-D1056) and Imiquimod (HY-B1080) induced inflammation .
2
2 Cited Publications
Cat. No.: HY-N0632
CAS No.: 65497-07-6
2
2 Cited Publications
Cat. No.: HY-P73094
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral OncoProtein 2 Isoform C; Receptor Tyrosine-Protein Kinase ErbB-2; V-Erb-B2 Avian Erythroblastic Leukemia Viral OncoProtein 2; Proto-Oncogene C-ErbB-2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Proto-Oncogene Neu; Receptor Tyrosine-Protein Kinase ErbB-2 Variant; P185(ErbB2); Truncated HER2 Splice Variant P100; C-ERB-2; Receptor Protein-Tyrosine Kinase; C-ERB2; Metastatic Lymph Node Gene 19; MLN-19; Alternative Protein ERBB2; HER-2; C-Erb B2/Neu Protein; CD340; CD340 Antigen; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; HER-2/Neu; Tyrosine Kinase-Type Cell Surface Receptor HER2; Herstatin; Neuro/Glioblastoma Derived Oncogene Homolog; VSCN2; Human Epidermal Growth Factor Receptor 2; MLN19; Metastatic Lymph Node Gene 19 Protein; TKR1; Erb-B2 Receptor Tyrosine Kinase 2; MLN 19
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P75236
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EPHB2; Ephrin Type-B Receptor 2 Variant; Prev. EPHT3; Protein-Tyrosine Kinase HEK5; Prev. DRT; Elk-Related Tyrosine Kinase; Prev. ERK; ELK-Related Tyrosine Kinase; Tyrosine-Protein Kinase Receptor EPH-3; Eph Tyrosine Kinase 3; Ephrin Type-B Receptor 2; EP
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-N9561
CAS No.: 155179-21-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
