9 Results for "

Prothionamide-d5

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Prothionamide-d5" in MCE Product Catalog:

1
1 Cited Publications
Art. -Nr.: HY-P1103
CAS. Nr.: 1030384-98-5
Target:  

CXCR

Forschungsgebiete:  

Cancer

CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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Art. -Nr.: HY-P4070
CAS. Nr.: 1188379-43-2
Target:  

Insulin Receptor

Forschungsgebiete:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
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Art. -Nr.: HY-B0306S
CAS. Nr.: 1330261-26-1
Synonyms: Protionamide-d5
Prothionamide-d5 is deuterium labeled Prothionamide (HY-B0306). Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a Km value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy [5].
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Art. -Nr.: HY-P1103A
Target:  

CXCR

Forschungsgebiete:  

Cancer

CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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Art. -Nr.: HY-P11293
CAS. Nr.: 1309855-53-5
Target:  

Melanocortin Receptor

Forschungsgebiete:  

Cancer

DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .
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Art. -Nr.: HY-P4757
CAS. Nr.: 108081-77-2
Target:  

Parasite

Forschungsgebiete:  

Others

N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
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Art. -Nr.: HY-P1321
CAS. Nr.: 158859-98-4
Synonyms: 1229U91; GW1229
Forschungsgebiete:  

Neurological Disease

GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
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Art. -Nr.: HY-P1321A
Synonyms: 1229U91 TFA; GW1229 TFA
Forschungsgebiete:  

Neurological Disease

GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
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Art. -Nr.: HY-P11480
CAS. Nr.: 3105660-96-3
Target:  

Trk Receptor

Forschungsgebiete:  

Neurological Disease

TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and NGF (IC50: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .
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