4 Results for "

Protodioscin

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Protodioscin" in MCE Product Catalog:

Protodioscin
Protodioscin
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Referencia número: HY-N0799
No. CAS: 55056-80-9
Category:  

Leguminosae Plants Endogenous metabolite Disease Research Fields Trigonella foenum-graecum Linn. Cancer Steroids

Target:  

Endogenous Metabolite

Protodioscin, a major steroidal saponin in Trigonella foenum-graecum Linn., has been shown to exhibit multiple biological actions, such as anti-hyperlipidemia, anti-cancer, sexual effects and cardiovascular properties.
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Methyl protodioscin
Methyl protodioscin
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Referencia número: HY-N0863
No. CAS: 54522-52-0
Synonyms: NSC-698790; Smilax saponin B
Category:  

other families Plants Disease Research Fields Cancer Steroids

Target:  

Bcl-2 Family Apoptosis Akt c-Myc ERK p38 MAPK JNK FOXO

Methyl protodioscin (NSC-698790; Smilax saponin B) is a multi-target, selective, steroidal diglycoside inhibitor with antitumor activity that induces cell cycle arrest. The mechanism of action of Methyl protodioscin is complex, involving the induction of G2/M cell cycle arrest, regulation of the Bcl-2/Bax apoptotic pathway, inhibition of the Akt1/c-Myc axis and MAPK/ERK signaling, while simultaneously downregulating ADAM15 and inducing FOXO1 to reduce cholesterol synthesis. It also inhibits the JNK/c-Jun pathway, reducing the production of inflammatory factors (IL-6, TNF-α). Methyl protodioscin exhibits significant antitumor (inhibiting proliferation, migration, invasion, and inducing apoptosis), anti-inflammatory, and anti-restenosis activities. Methyl protodioscin can be used in research on lung cancer, prostate cancer, pancreatic cancer, and other tumors, as well as inflammatory diseases such as airway inflammation and enteritis .
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Protodioscin (Standard)
Protodioscin (Standard)
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Referencia número: HY-N0799R
No. CAS: 55056-80-9
Category:  

Leguminosae Plants Endogenous metabolite Trigonella foenum-graecum Linn. Steroids

Target:  

Reference Standards Endogenous Metabolite

Protodioscin (Standard) is the analytical standard of Protodioscin. This product is intended for research and analytical applications. Protodioscin, a major steroidal saponin in Trigonella foenum-graecum Linn., has been shown to exhibit multiple biological actions, such as anti-hyperlipidemia, anti-cancer, sexual effects and cardiovascular properties.
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Huangjiangsu A
Huangjiangsu A
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Referencia número: HY-N4278
No. CAS: 1026020-27-8
Target:  

Reactive Oxygen Species (ROS)

Áreas de investigación:  

Inflammation/Immunology

Huangjiangsu A, pseudoprotodioscin, methyl protobioside, protodioscin, and protodeltonin, isolated from D. villosa. Huangjiangsu A has hepatoprotective potential against H2O2-induced cytotoxicity and ROS generation and could be promising as potential therapeutic agents for liver diseases .
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