Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
RBP4
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "RBP4" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
A 1120 is a high-affinity nonretinoid retinol-binding protein 4 (RBP4) antagonist with a Ki value of 8.3 nM. A 1120 disrupts the interaction between RBP4 and its binding partner transthyretin .
1
1
Target:
Research Areas:
RBP4 inhibitor 1 (compound 43b) is a potent and orally active retinol-binding protein 4 (RBP4) inhibitor with IC50s of 28 nM and 110 nM for human and mouse RBP4. RBP4 inhibitor 1 has a potent and long-lasting blood RBP4-level-reducing effect in mice .
Cat. No.: HY-147366
CAS No.: 260553-24-0
Target:
Research Areas:
RBP4 ligand-1 is a non-retinoid ligands for (RBP4) retinol-binding protein 4. The hRBP4SPA IC50 and RBP4-TTR FRET IC50 values are 0.23±0.11 and 0.13±0.12 μM in the radioligand binding assay and FRET assay, respectively .
Cat. No.: HY-RS16888
Target:
Research Areas:
Rbp4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rbp4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Synonyms: LBS-008; BPN-14967
Target:
Research Areas:
Tinlarebant (LBS-008) is an orally active non-retinoid RBP4 (retinol-binding protein 4) antagonist. Tinlarebant can be used for the research of the Stargardt disease .
Cat. No.: HY-RS11769
Target:
Research Areas:
RBP4 Human Pre-designed siRNA Set A contains three designed siRNAs for RBP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23330
Target:
Research Areas:
Rbp4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rbp4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-172232
CAS No.: 1911650-53-7
Target:
Research Areas:
STG-001 is a retinol binding protein 4 (RBP4) antagonist. STG-001 inhibits RBP4 to reduce the synthesis of retinal and diretinol, thereby preventing photoreceptor degeneration. STG-001 can be used in the study of sexually precocious nephropathy (STGD) .
Cat. No.: HY-185132
CAS No.: 3086854-73-8
Target:
Research Areas:
RBP4-IN-2 (Compound 14) is a RBP4 inhibitor. RBP4-IN-2 can reduce RBP4 in mouse plasma by more than 50%. RBP4-IN-2 can be used to study diseases where excessive lipofuscin accumulates in the retina .
Cat. No.: HY-185133
CAS No.: 3107328-23-1
Target:
Research Areas:
RBP4-IN-3 (Compound 38) is a retinol-binding protein 4 (RBP4) inhibitor. RBP4-IN-3 can be used in studies related to cardiovascular diseases and obesity.
Cat. No.: HY-182385
CAS No.: 1628945-93-6
Target:
Research Areas:
BPN-14136 is an orally effective retinol-binding protein 4 (RBP4) inhibitor. BPN-14136 inhibits the binding of retinol to RBP4 with an IC50 of 12.8 nM. BPN-14136 inhibits retinol-dependent RBP4-transthyretin interaction (IC50 = 43.6 nM) and reduces circulating plasma RBP4 levels in vivo. BPN-14136 decreases the formation of cytotoxic bisretinoids in retinal pigment epithelial cells. BPN-14136 can be used for the research of atrophic age-related macular degeneration and Stargardt disease .
Cat. No.: HY-P77171
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Retinol-Binding Protein 4; Plasma Retinol-Binding Protein; PRBP; RBP; RBP4
Species:
Source:
Cat. No.: HY-107633R
CAS No.: 1152782-19-8
Research Areas:
A 1120 (Standard) is the analytical standard of A 1120 (HY-107633). This product is intended for research and analytical applications. A 1120 is a high-affinity nonretinoid retinol-binding protein 4 (RBP4) antagonist with a Ki value of 8.3 nM. A 1120 disrupts the interaction between RBP4 and its binding partner transthyretin .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
