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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
RD2
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "RD2" in MCE Product Catalog:
Cat. No.: HY-N2516
CAS No.: 83480-64-2
Category:
Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae Extract
Target:
Synonyms: PNU-101387G; U-101387G
Target:
Research Areas:
Sonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively .
Cat. No.: HY-W007880
CAS No.: 22348-32-9
Synonyms: (R)-Diphenylprolinol
Target:
Research Areas:
(R)-D2PM ((R)-Diphenylprolinol) is an isomer of the psychoactive substance D2PM and a pyrrolidine analog .
Synonyms: (+)-AJ 76 hydrochloride; (1S,2R)-AJ 76 hydrochloride
Target:
Research Areas:
AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) is an antagonist of dopamine autoreceptor with pKi values of 6.95, 6.67, 6.37, 6.21 and 6.07 for hD3, hD4, hD2S, hD2L and rD2 receptors, respectively.
Cat. No.: HY-175504
CAS No.: 932544-59-7
Target:
Research Areas:
MLS6357 is a D3 dopamine receptor (D3R)-selective positive allosteric modulator (PAM)-antagonist. MLS6357 exhibits antagonist activity in the D3R-mediated and the BRET-based β-arrestin recruitment assay with IC50s of 13 and 14 μM, and no activity for other DAR subtypes (D1R/D2R/D4R/D5R) (IC50 > 100 μM). MLS6357 is also an antagonist in the D3R-mediated Go-BRET assay with an IC50 of 17 μM. MLS6357 can be used for the study of neuropsychiatric disorders, including substance use disorder .
Cat. No.: HY-123676
CAS No.: 170858-34-1
Synonyms: PNU-101387G mesylate; U-101387G mesylate
Target:
Research Areas:
Sonepiprazole mesylate is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively .
Cat. No.: HY-14328A
CAS No.: 170857-36-0
Synonyms: PNU-101387G hydrochloride; U-101387G hydrochloride
Target:
Research Areas:
Sonepiprazole (PNU-101387G) hydrochloride is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively .
Cat. No.: HY-129089
CAS No.: 81264-57-5
Target:
Research Areas:
(-)-MDO-NPA is an N-propylnorapomorphine analog and a D1R/D2R dual-target ligand. (-)-MDO-NPA has EC50 values of 1949 nM (D1R) and 520 nM (D2R) for β-arrestin. (-)-MDO-NPA has EC50 values of 717.5 nM (D1R) and 7.7 nM (D2R) for cAMP. (-)-MDO-NPA can be used in the research of dopamine-related diseases such as Parkinson’s disease .
Cat. No.: HY-175532
CAS No.: 3062458-27-6
Target:
Research Areas:
M4 mAChR Modulator-2 is an orally active, selective, brain-penetrant positive allosteric modulator (PAM) of the M4 muscarinic acetylcholine receptor (M4 mAChR) (EC50 = 513 nM). M4 mAChR Modulator-2 exhibits high target selectivity, showing negligible affinity and low inhibition rates for non-target receptors (D1R/D2R/D3R, 5-HT subtypes, κ/δ/μ opioid receptors, H1, M1/M2) while specifically binding to M4 mAChR with a Ki of 377 nM and an inhibition rate of 62.8%. M4 mAChR Modulator-2 reverses Dizocilpine (MK-801) (HY-15084B)-induced hyperlocomotion in mice. M4 mAChR Modulator-2 can be used for the study of schizophrenia
Cat. No.: HY-RS11218
Target:
Research Areas:
PRPH2 Human Pre-designed siRNA Set A contains three designed siRNAs for PRPH2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W007880A
CAS No.: 172152-19-1
Synonyms: (R)-Diphenylprolinol hydrochloride
Target:
Research Areas:
(R)-D2PM ((R)-Diphenylprolinol) hydrochloride is an isomer of the psychoactive substance D2PM and a pyrrolidine analog .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
