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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
RNP complex
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "RNP complex" in MCE Product Catalog:
Cat. No.: HY-175469
CAS No.: 2894060-67-2
Target:
Research Areas:
VNT-101 is an orally active influenza A (IAV) inhibitor. VNT-101 disrupts NP-NP PPI to block NP oligomerization and destabilize the viral ribonucleoprotein (RNP) complex, with potent antiviral activity across multiple influenza A subtypes. VNT-101 exhibits EC50 values of 4-5 nM in cellular cytopathic effect (CPE) assay, 4-8 nM in neuraminidase (NA) assay, and 21-45 nM in RNP assay. VNT-101 demonstrates robust in vivo antiviral efficacy in mice infected with lethal H1N1 virus. VNT-101 can be used for the study of influenza A infection .
Cat. No.: HY-184249
CAS No.: 1145869-35-7
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4'-C-Azido-2'-deoxy-2'-fluorocytidine is an antiviral agent. 4'-C-Azido-2'-deoxy-2'-fluorocytidine potently inhibits RNA synthesis of crude RSV RNP complexes with an IC50 of 0.1 μM. 4'-C-Azido-2'-deoxy-2'-fluorocytidine inhibits RSV replication in a subgenomic RSV replicon system. 4'-C-Azido-2'-deoxy-2'-fluorocytidine can be used for the research of respiratory syncytial virus (RSV) infection .
Cat. No.: HY-153269
CAS No.: 2248691-80-5
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Research Areas:
9-Methyl-SMN-C5 is a SMN2 pre-mRNA splicing modifier that corrects exon 7 splicing. 9-Methyl-SMN-C5 binds to ESE2 and the 5'-splice site of exon 7, and stabilizes the RNP complex. 9-Methyl-SMN-C5 induces chemical shift perturbations at the 5'-splice site of the exon 7-U1 snRNA duplex. 9-Methyl-SMN-C5 partially blocks the binding of hnRNP G to ESE2. 9-Methyl-SMN-C5 can be used for research on spinal muscular atrophy (SMA) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
