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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
RVG
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "RVG" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P5623
CAS No.: 115136-25-9
Synonyms: RVG29; RDP; Rabies Virus Glycoprotein-29
Target:
Research Areas:
14
14 Publications Verification
Synonyms: Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
Target:
Liposome Endogenous Metabolite ACSL Family Amino acid Transporter Ferroptosis Glutathione Peroxidase
Research Areas:
DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .
1
1 Cited Publications
Cat. No.: HY-172705
Research Areas:
DSPE-PEG2000-RVG29 is a PEG conjugate composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB), crosses the BBB, and mediates receptor-dependent transcytosis. DSPE-PEG2000-RVG29 can be used for brain-targeted drug delivery, surface modification of nanocarriers, as well as gene and nucleic acid delivery. DSPE-PEG2000-RVG29 is applicable to research related to hypoxic-ischemic brain injury, Parkinson's disease, and other conditions .
1
1 Cited Publications
Cat. No.: HY-P5623B
Synonyms: RVG29 TFA; RDP TFA; Rabies Virus Glycoprotein-29 TFA
Cat. No.: HY-P5623A
CAS No.: 1186105-01-0
Synonyms: RVG29-Cys; RDP-Cys; Rabies Virus Glycoprotein-29-Cys
Cat. No.: HY-P5623A1
Synonyms: RVG29-Cys acetate; RDP-Cys acetate; Rabies Virus Glycoprotein-29-Cys acetate
Cat. No.: HY-172706
Research Areas:
DSPE-PEG5000-RVG29 is a PEG compound which composed of DSPE and a Rabies virus glycoprotein 29 (RVG29). RVG29 can bind specifically to the nicotinic acetylcholine receptor (nAChR) at the blood-brain barrier (BBB) and cross over the BBB .
Cat. No.: HY-P4086
CAS No.: 1678417-57-6
Research Areas:
nAChR on neuronal cells to mediate receptor-mediated endocytosis and targeted siRNA delivery. Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) protects complexed siRNA from degradation, enhances transcellular siRNA delivery in neuronal cells, and promotes efficient, pecific gene silencing. Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) can be used for the researches of neurological disease and cancer .
Cat. No.: HY-172705A
DSPE-PEG3400-RVG29 is a PEG conjugate composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB), crosses the BBB, and mediates receptor-dependent transcytosis. DSPE-PEG3400-RVG29 can be used for brain-targeted drug delivery, surface modification of nanocarriers, as well as gene and nucleic acid delivery. DSPE-PEG3400-RVG29 is applicable to research related to hypoxic-ischemic brain injury, Parkinson's disease, and other conditions
Cat. No.: HY-172704
DSPE-PEG1000-RVG29 is a PEG compound which composed of DSPE and a Rabies virus glycoprotein 29 (RVG29). RVG29 can bind specifically to the nicotinic acetylcholine receptor (nAChR) at the blood-brain barrier (BBB) and cross over the BBB .
Cat. No.: HY-187325A
Cat. No.: HY-187242
Target:
Research Areas:
DMG-PEG1000-RVG29 is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and RVG29 peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) (HY-P5623) as the terminal targeting/functional ligand. DMG-PEG1000-RVG29 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against the nAChR α7 subunit on neurons and brain endothelial cells.
Cat. No.: HY-187242A
Target:
Research Areas:
DMG-PEG2000-RVG29 is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and RVG29 peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) (HY-P5623) as the terminal targeting/functional ligand. DMG-PEG2000-RVG29 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against the nAChR α7 subunit on neurons and brain endothelial cells.
Cat. No.: HY-187242B
Target:
Research Areas:
DMG-PEG3400-RVG29 is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 3400 Da, and RVG29 peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) (HY-P5623) as the terminal targeting/functional ligand. DMG-PEG3400-RVG29 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against the nAChR α7 subunit on neurons and brain endothelial cells.
Cat. No.: HY-187242C
Target:
Research Areas:
DMG-PEG5000-RVG29 is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 5000 Da, and RVG29 peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) (HY-P5623) as the terminal targeting/functional ligand. DMG-PEG5000-RVG29 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against the nAChR α7 subunit on neurons and brain endothelial cells.
Cat. No.: HY-187278
Target:
Research Areas:
DOPE-PEG1000-RVG29 is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and RVG29 peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) (HY-P5623) as the terminal targeting/functional ligand. DOPE-PEG1000-RVG29 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against the nAChR α7 subunit on neurons and brain endothelial cells.
Cat. No.: HY-187278A
Target:
Research Areas:
DOPE-PEG2000-RVG29 is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and RVG29 peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) (HY-P5623) as the terminal targeting/functional ligand. DOPE-PEG2000-RVG29 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against the nAChR α7 subunit on neurons and brain endothelial cells.
Cat. No.: HY-187278B
Target:
Research Areas:
DOPE-PEG3400-RVG29 is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 3400 Da, and RVG29 peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) (HY-P5623) as the terminal targeting/functional ligand. DOPE-PEG3400-RVG29 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against the nAChR α7 subunit on neurons and brain endothelial cells.
Cat. No.: HY-187278C
Target:
Research Areas:
DOPE-PEG5000-RVG29 is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 5000 Da, and RVG29 peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) (HY-P5623) as the terminal targeting/functional ligand. DOPE-PEG5000-RVG29 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against the nAChR α7 subunit on neurons and brain endothelial cells.
Cat. No.: HY-187314A
Target:
Research Areas:
DPPE-PEG2000-RVG29 is a functionalized PEGylated lipid conjugate composed of three modular components: dipalmitoylphosphatidylethanolamine (DPPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and RVG29 peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) (HY-P5623) as the terminal targeting/functional ligand. DPPE-PEG2000-RVG29 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against the nAChR α7 subunit on neurons and brain endothelial cells.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
