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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

Raji tumor cell

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Payload (1) CD47 (2) Drug Derivative (1) EBV (3) Interleukin Related (1) LAG-3 (1)
By Research Areas:	Cancer (7) Infection (1)

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Targets Recommended: Large Tumor Suppressor (LATS) TNF Receptor BRK Programmed Cell Death 4 (PDCD4) Itk TOPK NAMPT ALCAM/CD166 GDNF Receptor BCL6 Tim3 VISTA BMI1

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-79256

MMAF-OMe 1 Publications Verification Monomethyl auristatin F methyl ester	ADC Payload	Cancer
MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin. MMAF-Ome inhibits several tumor cell lines with IC₅₀s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4 ^-) cell lines, respectively.

HY-P99533

Urabrelimab 1 Publications Verification SRF-231; SRF231	CD47 Interleukin Related	Cancer
Urabrelimab (SRF231) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction .

HY-P991057

STI-6643	CD47	Cancer
STI-6643 is a fully human IgG4 antibody that targets CD47. STI-6643 blocks CD47-SIRPα interaction, and enables macrophage-mediated phagocytosis of tumor cells. STI-6643 shows anti-tumor activity in mouse lymphoma xenograft models. STI-6643 can be used for the research of Burkitt's lymphoma, solid tumors, relapsed or refractory tumors, and lymphoma. The isotype control for STI-6643 can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .

HY-P99736

Miptenalimab 1 Publications Verification BI-754111	LAG-3	Cancer
Miptenalimab (BI-754111) is an anti-human LAG-3 antibody (K_D: 88.6 nM for h LAG-3). Miptenalimab blocks the interaction of LAG-3 with its ligand MHC-II .

HY-N7507

Sempervirine	Others	Cancer
Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC₅₀ values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively .

HY-N13723

Methyl lucidenate D	EBV	Cancer
Methyl lucidenate D is a selective inhibitor of Epstein-Barr virus early antigen (EBV-EA) activation with an IC₅₀ of 290 mol ratio/32 pmol TPA. Methyl lucidenate D exerts potential anti-tumor promoting activity by inhibiting TPA-induced EBV-EA activation and maintains major Raji cell survival (70%) at effective concentrations. Methyl lucidenate D can be used in the field of cancer chemoprevention .

HY-N17354

Glycocitrine II	EBV	Infection
Glycocitrine II is an acridone alkaloid. Glycocitrine II can be isolated from the Rutaceous plants. Glycocitrine II inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced EBV-EA activation .

HY-N16853

Diepiserratenediol	Drug Derivative	Others
Diepiserratenediol is a natural triterpene.

HY-N18106

Amygdalinic acid	EBV	Cancer
Amygdalinic acid (Compound 3) is a glycoside. Amygdalinic acid can be isolated from Persicae Semen. Amygdalinic acid inhibits Epstein-Barr virus early antigen activation. Amygdalinic acid delays two-stage chemical carcinogenesis in mouse skin, reduces papilloma incidence .

Cat. No.	상품명	Target	Research Area	Image

HY-P99533

Urabrelimab 1 Publications Verification SRF-231; SRF231	CD47 Interleukin Related	Cancer
Urabrelimab (SRF231) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction .

HY-P991057

STI-6643	CD47	Cancer
STI-6643 is a fully human IgG4 antibody that targets CD47. STI-6643 blocks CD47-SIRPα interaction, and enables macrophage-mediated phagocytosis of tumor cells. STI-6643 shows anti-tumor activity in mouse lymphoma xenograft models. STI-6643 can be used for the research of Burkitt's lymphoma, solid tumors, relapsed or refractory tumors, and lymphoma. The isotype control for STI-6643 can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .

HY-P99736

Miptenalimab 1 Publications Verification BI-754111	LAG-3	Cancer
Miptenalimab (BI-754111) is an anti-human LAG-3 antibody (K_D: 88.6 nM for h LAG-3). Miptenalimab blocks the interaction of LAG-3 with its ligand MHC-II .

Sempervirine	Alkaloids Classification of Application Fields Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Disease Research Fields Indole Alkaloids Cancer Source Classification	Others
Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC₅₀ values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively .

Methyl lucidenate D	Triterpenes Structural Classification Terpenoids Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Source Classification	EBV
Methyl lucidenate D is a selective inhibitor of Epstein-Barr virus early antigen (EBV-EA) activation with an IC₅₀ of 290 mol ratio/32 pmol TPA. Methyl lucidenate D exerts potential anti-tumor promoting activity by inhibiting TPA-induced EBV-EA activation and maintains major Raji cell survival (70%) at effective concentrations. Methyl lucidenate D can be used in the field of cancer chemoprevention .

Glycocitrine II	Glycosmis parviflora Kurz. Structural Classification Monophenols Rutaceae Phenols Plants Source Classification	EBV
Glycocitrine II is an acridone alkaloid. Glycocitrine II can be isolated from the Rutaceous plants. Glycocitrine II inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced EBV-EA activation .

Diepiserratenediol	Lycopodiaceae Triterpenes Structural Classification Phlegmariurus carinatus (Desv.) Ching Terpenoids Plants Source Classification	Drug Derivative
Diepiserratenediol is a natural triterpene.

Amygdalinic acid	Structural Classification Prunus persica L. Ketones, Aldehydes, Acids Rosaceae Plants Source Classification	EBV
Amygdalinic acid (Compound 3) is a glycoside. Amygdalinic acid can be isolated from Persicae Semen. Amygdalinic acid inhibits Epstein-Barr virus early antigen activation. Amygdalinic acid delays two-stage chemical carcinogenesis in mouse skin, reduces papilloma incidence .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Raji tumor cell

Inhibitors & Agonists

Inhibitory Antibodies

NaturalProducts

Natural
Products