66 Results for "

Rhododendron molle G. Don

" in MedChemExpress (MCE) Product Catalog:
Products (66)

66 Results for "Rhododendron molle G. Don" in MCE Product Catalog:

18
18 Publications Verification
Art. -Nr.: HY-108357
CAS. Nr.: 157-03-9
Reinheit:  99.98%
Synonyms: L-6-Diazo-5-oxonorleucine; Don
Forschungsgebiete:  

Infection Cancer

6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
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9
9 Cited Publications
Art. -Nr.: HY-122218
CAS. Nr.: 1998725-11-3
Reinheit:  ≥98.0%
Target:  

Glutaminase

Forschungsgebiete:  

Neurological Disease

JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .
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7
7 Cited Publications
Art. -Nr.: HY-N0344
CAS. Nr.: 24211-30-1
Synonyms: (-)-Farrerol
Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects .
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1
1 Cited Publications
Art. -Nr.: HY-129140
CAS. Nr.: 171370-55-1
Delphinidin-3-O-arabinoside chloride is an anthocyanin chloride compound. It is formed by combining Delphinidin (an anthocyanin with a natural purple color) with the 3-O-arabinoside group. Delphinidin-3-O-arabinoside can be isolated from Rhododendron and is in the form of furanose .
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Art. -Nr.: HY-N11678
CAS. Nr.: 131180-21-7
Synonyms: Don-3-β-D-glucoside; Deoxynivalenol 3-glucoside
Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol (HY-N6684). Deoxynivalenol-3-β-D-glucoside exhibits lower toxicity than Deoxynivalenol in vitro and in vivo .
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Art. -Nr.: HY-121388
CAS. Nr.: 577-27-5
Reinheit:  ≥98.0%
Synonyms: (+)-Ledol
Ledol ((+)-Ledol) is an antifungal agent isolated from the volatile oil components of Rhododendron tomentosum. Ledol also acts as an expectorant and antitussive, while it can cause adverse reactions such as dizziness, nausea and vomiting .
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Art. -Nr.: HY-W099547
CAS. Nr.: 2197-63-9
Target:  

Liposome

Forschungsgebiete:  

Others

Dihexadecyl hydrogen phosphateIt is an organic compound belonging to phospholipids. It's often used as an emulsifier, which means it helps mix two substances together that don't usually mix well, such as oil and water. Dihexadecyl hydrogen phosphateIt has several applications in the food industry, especially in the production of processed foods where it improves texture and stability. Additionally, it has applications in the pharmaceutical industry where it can be used ain the generation of micelles, liposomes, and other types of artificial membranes.
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Art. -Nr.: HY-P991023
CAS. Nr.: 2911590-72-0
Synonyms: 6MW3211

Target:  

CD47 PD-1/PD-L1

Forschungsgebiete:  

Cancer

Safimestomig (6MW3211) is an CD47/PD-L1-targeting bispecific antibody. Safimestomig blocks CD47-mediated 'don't eat me' signaling and selectively binds to CD47 on tumor cells. Safimestomig blocks PD-L1-mediated immune checkpoint signaling. Safimestomig can be used for the research of cancer .
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Art. -Nr.: HY-D0854
CAS. Nr.: 3244-88-0
Synonyms: Acid Violet 19; Acid fuchsin sodium
Acid Red is a class of synthetic dyes commonly used in the textile, paper and ink industries. They are in the category of acid dyes, which means they are water soluble and have acidic properties. Acid Red dye produces bright, vibrant colors that don't fade easily, but are not as durable as some other dyes. They can be used to dye a wide variety of fibers including wool, silk and nylon, as well as paper and leather.
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Art. -Nr.: HY-N2154
CAS. Nr.: 37720-86-8
Rhodojaponin V is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity. Rhodojaponin V is the C-14 acetylation product of Rhodojaponen III. L-Aspartic aicd sodium is commonly used in the study of inflammatory conditions .
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Art. -Nr.: HY-N1308
CAS. Nr.: 1615-94-7
Synonyms: Simiaren-3β-ol; β-Simiarenol
Simiarenol is triterpene alcohol isolated from the Hong Kong species of rhododendron simiarum .
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Art. -Nr.: HY-N3706
CAS. Nr.: 15297-92-4
Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC50 value 0.41 mg/L .
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Art. -Nr.: HY-P11097
CAS. Nr.: 3056822-31-9
Target:  

CD47

Forschungsgebiete:  

Cardiovascular Disease Cancer

Pep-20 is a CD47 binder with a human Kd of 2.91 µM and a murine Kd of 3.63 µM. Pep-20 blocks the interaction between CD47 and SIRPα, with an IC50 of 24.56 µM for human targets and 12.03 µM for murine targets. Pep-20 also acts as a phagocytosis enhancer and an inducer of anti-tumor immune responses. By blocking the CD47/SIRPα interaction, Pep-20 reduces the tyrosine phosphorylation level of SIRPα, disrupts the inhibitory "don't eat me" signaling pathway, enhances macrophage-mediated phagocytosis of solid tumor cells and hematologic tumor cells, and promotes macrophage mobilization of anti-tumor T-cell responses. Pep-20 can be used in research related to solid tumors, hematologic malignancies, breast cancer, and pancreatic cancer .
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Art. -Nr.: HY-N10602
CAS. Nr.: 1486-66-4
Caryatin is a natural product found in Rhododendron simiarum, and Aeonium decorum. Caryatin shows anti-tumor activity .
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Art. -Nr.: HY-N3655
CAS. Nr.: 26488-24-4
Synonyms: NSC 255998
Cyclo(D-Phe-L-Pro) (NSC 255998) is a flavonoid product that can be isolated from Rhododendron mucronulatum .
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Art. -Nr.: HY-N6685
CAS. Nr.: 50722-38-8
Synonyms: 3-AcDon; 3-ADon
3-Acetyldeoxynivalenol (3-AcDON; 3ADON), a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative, is a brain-penetrant Fusarium mycotoxin. 3-Acetyldeoxynivalenol induces mRNA expression and production of inflammatory chemokine IL-8 in intestinal cells .
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Art. -Nr.: HY-N2152
CAS. Nr.: 26342-66-5
Rhodojaponin III is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity .
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Art. -Nr.: HY-N3692
CAS. Nr.: 82003-90-5
Synonyms: (+)-Daurichromenic acid
Daurichromenic acid is a chromene, which can be isolated from the leaves and twigs of Rhododendron dauricum. Daurichromenic acid has potent anti-HIV activity with an EC50 value of 0.00567 μg/mL .
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Art. -Nr.: HY-179120
CAS. Nr.: 3095661-21-2
Target:  

Myosin

Forschungsgebiete:  

Infection

ZJS178 is a novel inhibitor of myosin I. ZJS178 is a fungicide that has inhibitory activity against Fusarium graminearum and can reduce DON toxin synthesis. ZJS178 can be used for research on plant diseases such as wheat scab .
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Art. -Nr.: HY-108357R
CAS. Nr.: 157-03-9
Synonyms: L-6-Diazo-5-oxonorleucine (Standard); Don (Standard)
6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
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