2 Results for "

Ruminococcus torques

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Ruminococcus torques" in MCE Product Catalog:

Cat. No.: HY-E72069A
Research Areas:  

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Acetyl xylan esterase from ruminococcus flavefaciens (Recombinant) (EC 3.1.1.72) is a hydrolase that can catalyze deacetylation of xylans and xylo-oligosaccharides.
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Cat. No.: HY-N20707
CAS No.: 24312-00-3
Castalagin is an orally active natural product with multiple biological activities including antibacterial activity against bacteria and anti-leishmanial activity against Leishmania aethiopica. Castalagin exhibits inhibitory activity against PARP1 and DNA topoisomerase II, with an IC50 of 0.86 μM for bovine PARP1. Castalagin reduces poly (ADP-ribosyl) ation modification in cells. Castalagin binds to the cell envelope of Ruminococcus bromii, increases the ratio of CD8+/FOXP3+CD4+ T cells in the tumor microenvironment, and acts as a prebiotic to enhance the activity of anti-PD-1 therapy. Castalagin induces morphological changes in Leishmania aethiopica promastigotes and inhibits their proliferation. Castalagin inhibits PBP2a-mediated peptidoglycan layer stabilization, disrupts bacterial peptidoglycan assembly, and inhibits and disintegrates bacterial biofilms. Castalagin can be used in research related to diseases such as cancer, leishmaniasis, and bacterial infections .
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