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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
S23
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "S23" in MCE Product Catalog:
1
1 Cited Publications
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S-23 is an orally active selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 induces androgen receptor (AR)-mediated transcriptional activation in CV-1 cells. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats .
Cat. No.: HY-N7092S23
Synonyms: D(-)-Fructose-13C3-1
Cat. No.: HY-B0389S23
CAS No.: 478529-48-5
Synonyms: Glucose-d2-1; D-(+)-Glucose-d2-1; Dextrose-d2-1
Cat. No.: HY-165613
CAS No.: 656831-18-4
Synonyms: Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine
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Pam2Cys (Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine) is a TLR2 agonist and immunostimulant. Pam2Cys binds to TLR2 to activate dendritic cells and trigger the TLR2-dependent NF-κB signaling pathway. Pam2Cys also induces dendritic cell maturation by upregulating the expression of cell surface MHC II molecules. Pam2Cys activates innate immune signaling pathways, drives pro-inflammatory and antimicrobial responses, enhances the expression of macrophage activation markers, increases phagocytic activity, induces the release of IL-12 and pro-inflammatory cytokines, and polarizes macrophages into a pro-inflammatory, antimicrobial phenotype without interfering with IL-10-induced macrophage polarization. Pam2Cys also serves as the lipid moiety in synthetic lipopeptide vaccines and possesses self-adjuvant properties. Pam2Cys enhances the immunogenicity of conjugated peptide segments and induces cellular and humoral immune responses. However, it does not activate CD4 T cells in mouse splenocyte cultures when used alone. Pam2Cys activates pulmonary TLR2 signaling pathways, triggers innate immune responses, recruits neutrophils and macrophages, induces the secretion of various cytokines, alleviates symptoms and damages associated with influenza A virus infection in mice without impairing adaptive immunity. Pam2Cys can be used in studies related to tuberculosis and influenza A virus infection .
Category:
Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Food Research
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Cat. No.: HY-163273
CAS No.: 3011805-61-8
FGFR4-IN-17 (Compound (S)-23) is a piperazinyl diflurindan derivative containing pyridinyl. FGFR4-IN-17 is a FGFR inhibitor with IC50 values of 24.2, 16.1, 78.0, and 68.0 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. FGFR4-IN-17 has antitumor activity .
Cat. No.: HY-W010747
CAS No.: 201473-90-7
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Synonyms: SSHB
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(22S,23S)-Homobrassinolide is one of the most active brassinosteroids in inducing plant growth in various plant bioassay systems. (22S,23S)-Homobrassinolide shows Akt-dependent anabolic activity in rat skeletal muscle cells. Orally active .
Cat. No.: HY-W442377
CAS No.: 1146411-14-4
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(S)-2-(3-Bromophenyl)propanoic acid is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-N15080
CAS No.: 57528-68-4
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Cat. No.: HY-W547983
CAS No.: 2388503-71-5
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rel-Ethyl (2R,3S)-2,3-dimethylcyclopropanecarboxylate is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-112102R
CAS No.: 80483-89-2
Synonyms: SSHB (Standard)
Research Areas:
(22S,23S)-Homobrassinolide (Standard) is the analytical standard of (22S,23S)-Homobrassinolide. This product is intended for research and analytical applications. (22S,23S)-Homobrassinolide is one of the most active brassinosteroids in inducing plant growth in various plant bioassay systems. (22S,23S)-Homobrassinolide shows Akt-dependent anabolic activity in rat skeletal muscle cells. Orally active[1].
Cat. No.: HY-RS12234
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RPS23 Human Pre-designed siRNA Set A contains three designed siRNAs for RPS23 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-173416
Research Areas:
Anti-inflammatory agent 100 (Compound (+)-4S-23) is an anti-inflammatory agent. Anti-inflammatory agent 100 inhibits MAPK and NF-κB signaling, and also inhibits NF-κB pathway by suppressing the phosphorylation of IκB-α and blocking nuclear translocation of phosphorylated p65. Anti-inflammatory agent 100 inhibits NO production (IC50: 0.5 μM) and TNF-α, IL-6, IL-1β secretion .
Cat. No.: HY-76996S1
Cat. No.: HY-N10856
CAS No.: 425370-70-3
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Cat. No.: HY-N13704
CAS No.: 874287-87-3
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Cat. No.: HY-N13530
CAS No.: 1616120-83-2
Category:
Triterpenes Tetracyclic Triterpenoids Terpenoids Cucurbitaceae Plants Momordica charantia Linn.
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Cat. No.: HY-N13541
CAS No.: 1474062-47-9
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Cat. No.: HY-W743885
CAS No.: 54910-48-4
Synonyms: (3S)-Squalene oxide; (S)-2,3-Epoxysqualene
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
